Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients
Abstract Objective: To analyze data related to surgical treatment in patients with congenital heart defects (CHD) and Down syndrome (DS) based on information from International Quality Improvement Collaborative Database for Congenital Heart Disease (IQIC). Methods: Between July 1, 2010 and December 31, 2017, 139 patients with CHD and DS underwent surgery at Hospital de Base and Hospital da Criança e Maternidade de São José do Rio Preto (FUNFARME)/Faculdade de Medicina de São José do Rio Preto - SP (FAMERP). A quantitative, observational and cross-sectional study was performed in which the pre, intra and postoperative data were analyzed in an IQIC database. The data included gender, age, prematurity, weight, preoperative procedures, diagnosis, associated cardiac and non-cardiac anomalies, Risk Adjustment for Congenital Heart Surgery (RACHS-1), type of surgery, cardiopulmonary bypass (CPB), perfusion time, aortic clamping time and CPB temperature, bacterial sepsis, surgical site infection and other infections, length of stay in intensive care unit (ICU), length of hospital stay and in-hospital mortality. Results: The most prevalent procedures were complete atrioventricular septal defect repair (58 - 39.45%), followed by closure of ventricular septal defect (36 - 24.49%). The RACHS-1 categories 1, 2, 3 and 4 were distributed as 22 (15%); 49 (33.3%); 72 (49%) and 4 (2.7%), respectively. There were no procedures classified as categories 5 or 6. Bacterial sepsis occurred in 10.2% of cases, surgical site infection in 6.1%, other infections in 14.3%. The median length of ICU stay was 5 days and the median length of hospital stay was 11 days. In-hospital mortality was 6.8%. Conclusion: Surgical treatment in patients with CHD and DS usually does not require highly complex surgical procedures, but are affected by infectious complications, resulting in a longer ICU and hospital length of stay with considerable mortality.
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Sociedade Brasileira de Cirurgia Cardiovascular
2019
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oai:scielo:S0102-763820190001000032019-02-21Surgical Treatment for Congenital Heart Defects in Down Syndrome PatientsSantos,Fernando Cesar Gimenes BarbosaCroti,Ulisses AlexandreMarchi,Carlos Henrique DeMurakami,Alexandre NoboruBrachine,Juliana Dane PereiraBorim,Bruna CuryFinoti,Renata GeronGodoy,Moacir Fernandes de Down Syndrome Heart Defects, Congenital Database Abstract Objective: To analyze data related to surgical treatment in patients with congenital heart defects (CHD) and Down syndrome (DS) based on information from International Quality Improvement Collaborative Database for Congenital Heart Disease (IQIC). Methods: Between July 1, 2010 and December 31, 2017, 139 patients with CHD and DS underwent surgery at Hospital de Base and Hospital da Criança e Maternidade de São José do Rio Preto (FUNFARME)/Faculdade de Medicina de São José do Rio Preto - SP (FAMERP). A quantitative, observational and cross-sectional study was performed in which the pre, intra and postoperative data were analyzed in an IQIC database. The data included gender, age, prematurity, weight, preoperative procedures, diagnosis, associated cardiac and non-cardiac anomalies, Risk Adjustment for Congenital Heart Surgery (RACHS-1), type of surgery, cardiopulmonary bypass (CPB), perfusion time, aortic clamping time and CPB temperature, bacterial sepsis, surgical site infection and other infections, length of stay in intensive care unit (ICU), length of hospital stay and in-hospital mortality. Results: The most prevalent procedures were complete atrioventricular septal defect repair (58 - 39.45%), followed by closure of ventricular septal defect (36 - 24.49%). The RACHS-1 categories 1, 2, 3 and 4 were distributed as 22 (15%); 49 (33.3%); 72 (49%) and 4 (2.7%), respectively. There were no procedures classified as categories 5 or 6. Bacterial sepsis occurred in 10.2% of cases, surgical site infection in 6.1%, other infections in 14.3%. The median length of ICU stay was 5 days and the median length of hospital stay was 11 days. In-hospital mortality was 6.8%. Conclusion: Surgical treatment in patients with CHD and DS usually does not require highly complex surgical procedures, but are affected by infectious complications, resulting in a longer ICU and hospital length of stay with considerable mortality.info:eu-repo/semantics/openAccessSociedade Brasileira de Cirurgia CardiovascularBrazilian Journal of Cardiovascular Surgery v.34 n.1 20192019-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382019000100003en10.21470/1678-9741-2018-0358 |
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Santos,Fernando Cesar Gimenes Barbosa Croti,Ulisses Alexandre Marchi,Carlos Henrique De Murakami,Alexandre Noboru Brachine,Juliana Dane Pereira Borim,Bruna Cury Finoti,Renata Geron Godoy,Moacir Fernandes de |
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Santos,Fernando Cesar Gimenes Barbosa Croti,Ulisses Alexandre Marchi,Carlos Henrique De Murakami,Alexandre Noboru Brachine,Juliana Dane Pereira Borim,Bruna Cury Finoti,Renata Geron Godoy,Moacir Fernandes de Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients |
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Santos,Fernando Cesar Gimenes Barbosa Croti,Ulisses Alexandre Marchi,Carlos Henrique De Murakami,Alexandre Noboru Brachine,Juliana Dane Pereira Borim,Bruna Cury Finoti,Renata Geron Godoy,Moacir Fernandes de |
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Santos,Fernando Cesar Gimenes Barbosa |
title |
Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients |
title_short |
Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients |
title_full |
Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients |
title_fullStr |
Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients |
title_full_unstemmed |
Surgical Treatment for Congenital Heart Defects in Down Syndrome Patients |
title_sort |
surgical treatment for congenital heart defects in down syndrome patients |
description |
Abstract Objective: To analyze data related to surgical treatment in patients with congenital heart defects (CHD) and Down syndrome (DS) based on information from International Quality Improvement Collaborative Database for Congenital Heart Disease (IQIC). Methods: Between July 1, 2010 and December 31, 2017, 139 patients with CHD and DS underwent surgery at Hospital de Base and Hospital da Criança e Maternidade de São José do Rio Preto (FUNFARME)/Faculdade de Medicina de São José do Rio Preto - SP (FAMERP). A quantitative, observational and cross-sectional study was performed in which the pre, intra and postoperative data were analyzed in an IQIC database. The data included gender, age, prematurity, weight, preoperative procedures, diagnosis, associated cardiac and non-cardiac anomalies, Risk Adjustment for Congenital Heart Surgery (RACHS-1), type of surgery, cardiopulmonary bypass (CPB), perfusion time, aortic clamping time and CPB temperature, bacterial sepsis, surgical site infection and other infections, length of stay in intensive care unit (ICU), length of hospital stay and in-hospital mortality. Results: The most prevalent procedures were complete atrioventricular septal defect repair (58 - 39.45%), followed by closure of ventricular septal defect (36 - 24.49%). The RACHS-1 categories 1, 2, 3 and 4 were distributed as 22 (15%); 49 (33.3%); 72 (49%) and 4 (2.7%), respectively. There were no procedures classified as categories 5 or 6. Bacterial sepsis occurred in 10.2% of cases, surgical site infection in 6.1%, other infections in 14.3%. The median length of ICU stay was 5 days and the median length of hospital stay was 11 days. In-hospital mortality was 6.8%. Conclusion: Surgical treatment in patients with CHD and DS usually does not require highly complex surgical procedures, but are affected by infectious complications, resulting in a longer ICU and hospital length of stay with considerable mortality. |
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Sociedade Brasileira de Cirurgia Cardiovascular |
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2019 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382019000100003 |
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