Two new diterpenoids from Leonurus japonicus

Two new diterpenoids from Leonurus japonicus

Abstract Two new labdane-type diterpenoids, 5-ethoxy-3-(2-((R)-4-hydroxy-2,5,5,8a-tetramethyl-3-oxo-3,5,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)furan-2(5H)-one (1), and 5-hydroxy-4-(2-((1R,3S,7aS)-1-hydroxy-4,4,7a-trimethyl-3-propionyloctahydroisobenzofuran-1-yl)ethyl)furan-2(5H)-one (2), were isolated from the EtOH extract of the herb of Leonurus japonicus Houtt., Lamiaceae. Their chemical structures were determined by analysis of 1D, 2D NMR, HRESIMS, and by comparison with known analogs.

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Bibliographic Details
Main Authors: Wu,Hankui, Wang,Sensheng, Liu,Haijuan, E,Yan, Li,Yan, Liu,Ruijin, Wang,Jinjin, Xu,Zhiyong, Lv,Yanyan, Sun,Shanshan, Li,Gang, Shi,Yunfeng
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Farmacognosia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000200180
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spelling oai:scielo:S0102-695X20150002001802015-06-23Two new diterpenoids from Leonurus japonicusWu,HankuiWang,SenshengLiu,HaijuanE,YanLi,YanLiu,RuijinWang,JinjinXu,ZhiyongLv,YanyanSun,ShanshanLi,GangShi,Yunfeng Leonurus japonicus Labdane diterpenoid Abstract Two new labdane-type diterpenoids, 5-ethoxy-3-(2-((R)-4-hydroxy-2,5,5,8a-tetramethyl-3-oxo-3,5,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)furan-2(5H)-one (1), and 5-hydroxy-4-(2-((1R,3S,7aS)-1-hydroxy-4,4,7a-trimethyl-3-propionyloctahydroisobenzofuran-1-yl)ethyl)furan-2(5H)-one (2), were isolated from the EtOH extract of the herb of Leonurus japonicus Houtt., Lamiaceae. Their chemical structures were determined by analysis of 1D, 2D NMR, HRESIMS, and by comparison with known analogs.info:eu-repo/semantics/openAccessSociedade Brasileira de FarmacognosiaRevista Brasileira de Farmacognosia v.25 n.2 20152015-04-01info:eu-repo/semantics/othertext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000200180en10.1016/j.bjp.2015.02.006
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Wu,Hankui
Wang,Sensheng
Liu,Haijuan
E,Yan
Li,Yan
Liu,Ruijin
Wang,Jinjin
Xu,Zhiyong
Lv,Yanyan
Sun,Shanshan
Li,Gang
Shi,Yunfeng
spellingShingle Wu,Hankui
Wang,Sensheng
Liu,Haijuan
E,Yan
Li,Yan
Liu,Ruijin
Wang,Jinjin
Xu,Zhiyong
Lv,Yanyan
Sun,Shanshan
Li,Gang
Shi,Yunfeng
Two new diterpenoids from Leonurus japonicus
author_facet Wu,Hankui
Wang,Sensheng
Liu,Haijuan
E,Yan
Li,Yan
Liu,Ruijin
Wang,Jinjin
Xu,Zhiyong
Lv,Yanyan
Sun,Shanshan
Li,Gang
Shi,Yunfeng
author_sort Wu,Hankui
title Two new diterpenoids from Leonurus japonicus
title_short Two new diterpenoids from Leonurus japonicus
title_full Two new diterpenoids from Leonurus japonicus
title_fullStr Two new diterpenoids from Leonurus japonicus
title_full_unstemmed Two new diterpenoids from Leonurus japonicus
title_sort two new diterpenoids from leonurus japonicus
description Abstract Two new labdane-type diterpenoids, 5-ethoxy-3-(2-((R)-4-hydroxy-2,5,5,8a-tetramethyl-3-oxo-3,5,6,7,8,8a-hexahydronaphthalen-1-yl)ethyl)furan-2(5H)-one (1), and 5-hydroxy-4-(2-((1R,3S,7aS)-1-hydroxy-4,4,7a-trimethyl-3-propionyloctahydroisobenzofuran-1-yl)ethyl)furan-2(5H)-one (2), were isolated from the EtOH extract of the herb of Leonurus japonicus Houtt., Lamiaceae. Their chemical structures were determined by analysis of 1D, 2D NMR, HRESIMS, and by comparison with known analogs.
publisher Sociedade Brasileira de Farmacognosia
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2015000200180
work_keys_str_mv AT wuhankui twonewditerpenoidsfromleonurusjaponicus
AT wangsensheng twonewditerpenoidsfromleonurusjaponicus
AT liuhaijuan twonewditerpenoidsfromleonurusjaponicus
AT eyan twonewditerpenoidsfromleonurusjaponicus
AT liyan twonewditerpenoidsfromleonurusjaponicus
AT liuruijin twonewditerpenoidsfromleonurusjaponicus
AT wangjinjin twonewditerpenoidsfromleonurusjaponicus
AT xuzhiyong twonewditerpenoidsfromleonurusjaponicus
AT lvyanyan twonewditerpenoidsfromleonurusjaponicus
AT sunshanshan twonewditerpenoidsfromleonurusjaponicus
AT ligang twonewditerpenoidsfromleonurusjaponicus
AT shiyunfeng twonewditerpenoidsfromleonurusjaponicus
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