The role of surgery in the management of women with gestational trophoblastic disease

The role of surgery in the management of women with gestational trophoblastic disease

ABSTRACT The Gestational Trophoblastic Disease includes an interrelated group of diseases originating from placental tissue, with distinct behaviors concerning local invasion and metastasis. The high sensitivity of the serial dosages of human chorionic gonadotrophin, combined with advances in chemotherapy treatment, have made gestational trophoblastic neoplasia curable, most often through chemotherapy. However, surgery remains of major importance in the management of patients with gestational trophoblastic disease, improving their prognosis. Surgery is necessary in the control of the disease's complications, such as hemorrhage, and in cases of resistant/relapsed neoplasia. This review discusses the indications and the role of surgical interventions in the management of women with molar pregnancy and gestational trophoblastic neoplasia.

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Main Authors: LIMA,LANA DE LOURDES AGUIAR, PADRON,LÍLIAN, CÂMARA,RAPHAEL, SUN,SUE YAZAKI, REZENDE FILHO,JORGE, BRAGA,ANTÔNIO
Format: Digital revista
Language:English
Published: Colégio Brasileiro de Cirurgiões 2017
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912017000100094
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spelling oai:scielo:S0100-699120170001000942017-04-19The role of surgery in the management of women with gestational trophoblastic diseaseLIMA,LANA DE LOURDES AGUIARPADRON,LÍLIANCÂMARA,RAPHAELSUN,SUE YAZAKIREZENDE FILHO,JORGEBRAGA,ANTÔNIO Gestational Trophoblastic Disease General Surgery Hysterectomy Thoracotomy Craniotomy ABSTRACT The Gestational Trophoblastic Disease includes an interrelated group of diseases originating from placental tissue, with distinct behaviors concerning local invasion and metastasis. The high sensitivity of the serial dosages of human chorionic gonadotrophin, combined with advances in chemotherapy treatment, have made gestational trophoblastic neoplasia curable, most often through chemotherapy. However, surgery remains of major importance in the management of patients with gestational trophoblastic disease, improving their prognosis. Surgery is necessary in the control of the disease's complications, such as hemorrhage, and in cases of resistant/relapsed neoplasia. This review discusses the indications and the role of surgical interventions in the management of women with molar pregnancy and gestational trophoblastic neoplasia.info:eu-repo/semantics/openAccessColégio Brasileiro de CirurgiõesRevista do Colégio Brasileiro de Cirurgiões v.44 n.1 20172017-02-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912017000100094en10.1590/0100-69912017001009
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libraryname SciELO
language English
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author LIMA,LANA DE LOURDES AGUIAR
PADRON,LÍLIAN
CÂMARA,RAPHAEL
SUN,SUE YAZAKI
REZENDE FILHO,JORGE
BRAGA,ANTÔNIO
spellingShingle LIMA,LANA DE LOURDES AGUIAR
PADRON,LÍLIAN
CÂMARA,RAPHAEL
SUN,SUE YAZAKI
REZENDE FILHO,JORGE
BRAGA,ANTÔNIO
The role of surgery in the management of women with gestational trophoblastic disease
author_facet LIMA,LANA DE LOURDES AGUIAR
PADRON,LÍLIAN
CÂMARA,RAPHAEL
SUN,SUE YAZAKI
REZENDE FILHO,JORGE
BRAGA,ANTÔNIO
author_sort LIMA,LANA DE LOURDES AGUIAR
title The role of surgery in the management of women with gestational trophoblastic disease
title_short The role of surgery in the management of women with gestational trophoblastic disease
title_full The role of surgery in the management of women with gestational trophoblastic disease
title_fullStr The role of surgery in the management of women with gestational trophoblastic disease
title_full_unstemmed The role of surgery in the management of women with gestational trophoblastic disease
title_sort role of surgery in the management of women with gestational trophoblastic disease
description ABSTRACT The Gestational Trophoblastic Disease includes an interrelated group of diseases originating from placental tissue, with distinct behaviors concerning local invasion and metastasis. The high sensitivity of the serial dosages of human chorionic gonadotrophin, combined with advances in chemotherapy treatment, have made gestational trophoblastic neoplasia curable, most often through chemotherapy. However, surgery remains of major importance in the management of patients with gestational trophoblastic disease, improving their prognosis. Surgery is necessary in the control of the disease's complications, such as hemorrhage, and in cases of resistant/relapsed neoplasia. This review discusses the indications and the role of surgical interventions in the management of women with molar pregnancy and gestational trophoblastic neoplasia.
publisher Colégio Brasileiro de Cirurgiões
publishDate 2017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912017000100094
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