The cost of excessive postoperative use of antimicrobials: the context of a public hospital

The cost of excessive postoperative use of antimicrobials: the context of a public hospital

OBJECTIVE: To evaluate the improper use of antimicrobials during the postoperative period and its economic impact.METHODS: We conducted a prospective cohort study by collecting data from medical records of 237 patients operated on between 01/11/08 and 31/12/08.RESULTS: from the 237 patients with the information collected, 217 (91.56%) received antimicrobials. During the postoperative period, 125 (57.7%) patients received more than two antimicrobials. On average, 1.7 ± 0.6 antimicrobials were prescribed to patients, the most commonly prescribed antibiotic being cephalothin, in 41.5% (154) of cases. The direct cost of antimicrobial therapy accounted for 63.78% of all drug therapy, this large percentage being attributed in part to the extended antimicrobial prophylaxis. In the case of clean operations, where there was a mean duration of 5.2 days of antibiotics, antimicrobials represented 44.3% of the total therapy cost.CONCLUSION: The data illustrate the impact of overuse of antimicrobials, with questionable indications, creating situations that compromise patient safety and increasing costs in the assessed hospital.

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Main Authors: Santana,Rafael Santos, Viana,Ariane de Carvalho, Santiago,Jozimário da Silva, Menezes,Michelle Santos, Lobo,Iza Maria Fraga, Marcellini,Paulo Sergio
Format: Digital revista
Language:English
Published: Colégio Brasileiro de Cirurgiões 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912014000300149
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spelling oai:scielo:S0100-699120140003001492015-09-25The cost of excessive postoperative use of antimicrobials: the context of a public hospitalSantana,Rafael SantosViana,Ariane de CarvalhoSantiago,Jozimário da SilvaMenezes,Michelle SantosLobo,Iza Maria FragaMarcellini,Paulo Sergio Anti-infective agents Drug utilization Anti-bacterial agents/administration & dosage Health care costs Economics, medical OBJECTIVE: To evaluate the improper use of antimicrobials during the postoperative period and its economic impact.METHODS: We conducted a prospective cohort study by collecting data from medical records of 237 patients operated on between 01/11/08 and 31/12/08.RESULTS: from the 237 patients with the information collected, 217 (91.56%) received antimicrobials. During the postoperative period, 125 (57.7%) patients received more than two antimicrobials. On average, 1.7 ± 0.6 antimicrobials were prescribed to patients, the most commonly prescribed antibiotic being cephalothin, in 41.5% (154) of cases. The direct cost of antimicrobial therapy accounted for 63.78% of all drug therapy, this large percentage being attributed in part to the extended antimicrobial prophylaxis. In the case of clean operations, where there was a mean duration of 5.2 days of antibiotics, antimicrobials represented 44.3% of the total therapy cost.CONCLUSION: The data illustrate the impact of overuse of antimicrobials, with questionable indications, creating situations that compromise patient safety and increasing costs in the assessed hospital.info:eu-repo/semantics/openAccessColégio Brasileiro de CirurgiõesRevista do Colégio Brasileiro de Cirurgiões v.41 n.3 20142014-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912014000300149en10.1590/S0100-69912014000300003
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Santana,Rafael Santos
Viana,Ariane de Carvalho
Santiago,Jozimário da Silva
Menezes,Michelle Santos
Lobo,Iza Maria Fraga
Marcellini,Paulo Sergio
spellingShingle Santana,Rafael Santos
Viana,Ariane de Carvalho
Santiago,Jozimário da Silva
Menezes,Michelle Santos
Lobo,Iza Maria Fraga
Marcellini,Paulo Sergio
The cost of excessive postoperative use of antimicrobials: the context of a public hospital
author_facet Santana,Rafael Santos
Viana,Ariane de Carvalho
Santiago,Jozimário da Silva
Menezes,Michelle Santos
Lobo,Iza Maria Fraga
Marcellini,Paulo Sergio
author_sort Santana,Rafael Santos
title The cost of excessive postoperative use of antimicrobials: the context of a public hospital
title_short The cost of excessive postoperative use of antimicrobials: the context of a public hospital
title_full The cost of excessive postoperative use of antimicrobials: the context of a public hospital
title_fullStr The cost of excessive postoperative use of antimicrobials: the context of a public hospital
title_full_unstemmed The cost of excessive postoperative use of antimicrobials: the context of a public hospital
title_sort cost of excessive postoperative use of antimicrobials: the context of a public hospital
description OBJECTIVE: To evaluate the improper use of antimicrobials during the postoperative period and its economic impact.METHODS: We conducted a prospective cohort study by collecting data from medical records of 237 patients operated on between 01/11/08 and 31/12/08.RESULTS: from the 237 patients with the information collected, 217 (91.56%) received antimicrobials. During the postoperative period, 125 (57.7%) patients received more than two antimicrobials. On average, 1.7 ± 0.6 antimicrobials were prescribed to patients, the most commonly prescribed antibiotic being cephalothin, in 41.5% (154) of cases. The direct cost of antimicrobial therapy accounted for 63.78% of all drug therapy, this large percentage being attributed in part to the extended antimicrobial prophylaxis. In the case of clean operations, where there was a mean duration of 5.2 days of antibiotics, antimicrobials represented 44.3% of the total therapy cost.CONCLUSION: The data illustrate the impact of overuse of antimicrobials, with questionable indications, creating situations that compromise patient safety and increasing costs in the assessed hospital.
publisher Colégio Brasileiro de Cirurgiões
publishDate 2014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-69912014000300149
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