Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi

Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi

Congenitally athymic nude Balb/c (nu/nu) and their phenothypically normal adult and neonate littermates (nu/+), the C3H/HeN as well, were intraperitoneally infected with two strains (Y or CL) of Trypanossoma cruzi. The nude mice and the neonates developed a severe parasitaemia, the susceptible C3H/HeN also presented high level and adult Balb/c mice presented parasitaemia similar to that observed in outbred mice. Erythematous skin lesions were observed initially in infected athymic nude and neonates, being charactherized by nests of amastigotes in the dermis; in C3H/HeN infected mice no nest of parasite was observed but a low-grade inflammatory reaction was seen. In adult Balb/c or OF1 outbred mice nest was found but discreet inflammatory reaction was observed in severe infections.

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Main Authors: Costa,Sylvio Celso Gonçalves da, Calabrese,Kátia da Silva
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1992
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000500015
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spelling oai:scielo:S0074-027619920005000152009-06-15Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruziCosta,Sylvio Celso Gonçalves daCalabrese,Kátia da Silva Trypanosoma cruzi dermatitis immunodeficience schizotrypanids nude mice Congenitally athymic nude Balb/c (nu/nu) and their phenothypically normal adult and neonate littermates (nu/+), the C3H/HeN as well, were intraperitoneally infected with two strains (Y or CL) of Trypanossoma cruzi. The nude mice and the neonates developed a severe parasitaemia, the susceptible C3H/HeN also presented high level and adult Balb/c mice presented parasitaemia similar to that observed in outbred mice. Erythematous skin lesions were observed initially in infected athymic nude and neonates, being charactherized by nests of amastigotes in the dermis; in C3H/HeN infected mice no nest of parasite was observed but a low-grade inflammatory reaction was seen. In adult Balb/c or OF1 outbred mice nest was found but discreet inflammatory reaction was observed in severe infections.info:eu-repo/semantics/openAccessInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz v.87 suppl.1 19921992-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000500015en10.1590/S0074-02761992000500015
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Costa,Sylvio Celso Gonçalves da
Calabrese,Kátia da Silva
spellingShingle Costa,Sylvio Celso Gonçalves da
Calabrese,Kátia da Silva
Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi
author_facet Costa,Sylvio Celso Gonçalves da
Calabrese,Kátia da Silva
author_sort Costa,Sylvio Celso Gonçalves da
title Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi
title_short Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi
title_full Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi
title_fullStr Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi
title_full_unstemmed Schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with Trypanosoma cruzi
title_sort schizotrypanids: the occurence of dermatitis in immunodeficiency animals infected with trypanosoma cruzi
description Congenitally athymic nude Balb/c (nu/nu) and their phenothypically normal adult and neonate littermates (nu/+), the C3H/HeN as well, were intraperitoneally infected with two strains (Y or CL) of Trypanossoma cruzi. The nude mice and the neonates developed a severe parasitaemia, the susceptible C3H/HeN also presented high level and adult Balb/c mice presented parasitaemia similar to that observed in outbred mice. Erythematous skin lesions were observed initially in infected athymic nude and neonates, being charactherized by nests of amastigotes in the dermis; in C3H/HeN infected mice no nest of parasite was observed but a low-grade inflammatory reaction was seen. In adult Balb/c or OF1 outbred mice nest was found but discreet inflammatory reaction was observed in severe infections.
publisher Instituto Oswaldo Cruz, Ministério da Saúde
publishDate 1992
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000500015
work_keys_str_mv AT costasylviocelsogoncalvesda schizotrypanidstheoccurenceofdermatitisinimmunodeficiencyanimalsinfectedwithtrypanosomacruzi
AT calabresekatiadasilva schizotrypanidstheoccurenceofdermatitisinimmunodeficiencyanimalsinfectedwithtrypanosomacruzi
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