COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is an unusual cutaneous reaction, most often related with a hypersensitivity reaction to commonly used drugs. It is characterized by an abrupt onset of a pustular rash within hours or days after drug exposure and usually resolves spontaneously within 1-2 weeks after drug discontinuation. Some cases associated with systemic involvement and shock have been reported. We present the case of a severe AGEP, manifesting in association with systemic involvement and haemodynamic instability resulting in shock and multiorgan dysfunction in an adult female patient diagnosed with COVID-19 infection. There were no identifiable associated drugs, and the patient was not initiated on antimalarial drugs. Our patient improved rapidly, both hemodynamically and dermatologically with no directed therapy.
Main Authors: | , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Instituto de Medicina Tropical de São Paulo
2021
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652021000100507 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S0036-46652021000100507 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S0036-466520210001005072021-05-20COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patientOrdoñez,Nicolás ArizaSepulveda,Valeria GomezVargas,Lina PatriciaMoreno,Julian Mauricio COVID-19 Skin manifestations SARS CoV-2 Shock ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is an unusual cutaneous reaction, most often related with a hypersensitivity reaction to commonly used drugs. It is characterized by an abrupt onset of a pustular rash within hours or days after drug exposure and usually resolves spontaneously within 1-2 weeks after drug discontinuation. Some cases associated with systemic involvement and shock have been reported. We present the case of a severe AGEP, manifesting in association with systemic involvement and haemodynamic instability resulting in shock and multiorgan dysfunction in an adult female patient diagnosed with COVID-19 infection. There were no identifiable associated drugs, and the patient was not initiated on antimalarial drugs. Our patient improved rapidly, both hemodynamically and dermatologically with no directed therapy.info:eu-repo/semantics/openAccessInstituto de Medicina Tropical de São PauloRevista do Instituto de Medicina Tropical de São Paulo v.63 20212021-01-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652021000100507en10.1590/s1678-9946202163042 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Ordoñez,Nicolás Ariza Sepulveda,Valeria Gomez Vargas,Lina Patricia Moreno,Julian Mauricio |
spellingShingle |
Ordoñez,Nicolás Ariza Sepulveda,Valeria Gomez Vargas,Lina Patricia Moreno,Julian Mauricio COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient |
author_facet |
Ordoñez,Nicolás Ariza Sepulveda,Valeria Gomez Vargas,Lina Patricia Moreno,Julian Mauricio |
author_sort |
Ordoñez,Nicolás Ariza |
title |
COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient |
title_short |
COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient |
title_full |
COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient |
title_fullStr |
COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient |
title_full_unstemmed |
COVID-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient |
title_sort |
covid-19 presenting as acute generalized exanthematous pustulosis associated with multiorgan dysfunction in a 44-year-old female patient |
description |
ABSTRACT Acute generalised exanthematous pustulosis (AGEP) is an unusual cutaneous reaction, most often related with a hypersensitivity reaction to commonly used drugs. It is characterized by an abrupt onset of a pustular rash within hours or days after drug exposure and usually resolves spontaneously within 1-2 weeks after drug discontinuation. Some cases associated with systemic involvement and shock have been reported. We present the case of a severe AGEP, manifesting in association with systemic involvement and haemodynamic instability resulting in shock and multiorgan dysfunction in an adult female patient diagnosed with COVID-19 infection. There were no identifiable associated drugs, and the patient was not initiated on antimalarial drugs. Our patient improved rapidly, both hemodynamically and dermatologically with no directed therapy. |
publisher |
Instituto de Medicina Tropical de São Paulo |
publishDate |
2021 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652021000100507 |
work_keys_str_mv |
AT ordoneznicolasariza covid19presentingasacutegeneralizedexanthematouspustulosisassociatedwithmultiorgandysfunctionina44yearoldfemalepatient AT sepulvedavaleriagomez covid19presentingasacutegeneralizedexanthematouspustulosisassociatedwithmultiorgandysfunctionina44yearoldfemalepatient AT vargaslinapatricia covid19presentingasacutegeneralizedexanthematouspustulosisassociatedwithmultiorgandysfunctionina44yearoldfemalepatient AT morenojulianmauricio covid19presentingasacutegeneralizedexanthematouspustulosisassociatedwithmultiorgandysfunctionina44yearoldfemalepatient |
_version_ |
1756379979491311616 |