Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo
Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.
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Sociedad Médica de Santiago
2020
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oai:scielo:S0034-988720200007009832020-10-09Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejoFoncea,Camilavon Bischhoffshausen,KristineTeuber,CristiánRamírez,HernánGoñi,IgnacioSánchez,CesarRetamal,Ignacio N.Vargas,Alex Osteonecrosis Angiogenesis Inhibitors Bisphosphonate-Associated Osteonecrosis of the Jaw Bone Density Conservation Agents Diphosphonates Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.7 20202020-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000700983es10.4067/S0034-98872020000700983 |
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Foncea,Camila von Bischhoffshausen,Kristine Teuber,Cristián Ramírez,Hernán Goñi,Ignacio Sánchez,Cesar Retamal,Ignacio N. Vargas,Alex |
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Foncea,Camila von Bischhoffshausen,Kristine Teuber,Cristián Ramírez,Hernán Goñi,Ignacio Sánchez,Cesar Retamal,Ignacio N. Vargas,Alex Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo |
author_facet |
Foncea,Camila von Bischhoffshausen,Kristine Teuber,Cristián Ramírez,Hernán Goñi,Ignacio Sánchez,Cesar Retamal,Ignacio N. Vargas,Alex |
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Foncea,Camila |
title |
Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo |
title_short |
Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo |
title_full |
Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo |
title_fullStr |
Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo |
title_full_unstemmed |
Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo |
title_sort |
osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo |
description |
Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients. |
publisher |
Sociedad Médica de Santiago |
publishDate |
2020 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000700983 |
work_keys_str_mv |
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