Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo

Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.

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Main Authors: Foncea,Camila, von Bischhoffshausen,Kristine, Teuber,Cristián, Ramírez,Hernán, Goñi,Ignacio, Sánchez,Cesar, Retamal,Ignacio N., Vargas,Alex
Format: Digital revista
Language:Spanish / Castilian
Published: Sociedad Médica de Santiago 2020
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000700983
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spelling oai:scielo:S0034-988720200007009832020-10-09Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejoFoncea,Camilavon Bischhoffshausen,KristineTeuber,CristiánRamírez,HernánGoñi,IgnacioSánchez,CesarRetamal,Ignacio N.Vargas,Alex Osteonecrosis Angiogenesis Inhibitors Bisphosphonate-Associated Osteonecrosis of the Jaw Bone Density Conservation Agents Diphosphonates Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.7 20202020-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000700983es10.4067/S0034-98872020000700983
institution SCIELO
collection OJS
country Chile
countrycode CL
component Revista
access En linea
databasecode rev-scielo-cl
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region America del Sur
libraryname SciELO
language Spanish / Castilian
format Digital
author Foncea,Camila
von Bischhoffshausen,Kristine
Teuber,Cristián
Ramírez,Hernán
Goñi,Ignacio
Sánchez,Cesar
Retamal,Ignacio N.
Vargas,Alex
spellingShingle Foncea,Camila
von Bischhoffshausen,Kristine
Teuber,Cristián
Ramírez,Hernán
Goñi,Ignacio
Sánchez,Cesar
Retamal,Ignacio N.
Vargas,Alex
Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo
author_facet Foncea,Camila
von Bischhoffshausen,Kristine
Teuber,Cristián
Ramírez,Hernán
Goñi,Ignacio
Sánchez,Cesar
Retamal,Ignacio N.
Vargas,Alex
author_sort Foncea,Camila
title Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo
title_short Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo
title_full Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo
title_fullStr Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo
title_full_unstemmed Osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo
title_sort osteonecrosis de los maxilares asociada a medicamentos: revisión de la literatura y propuesta para la prevención y manejo
description Medication-related osteonecrosis of the jaw is a disease where there is necrotic bone exposed or that can be explored by means of a fistula in the maxillofacial region. It has been associated with the use Biphosphonates and denosumab for osteoporosis. Although its etiology is unclear, it may be related to a decrease in bone turnover produced by these drugs, rendering the bone more prone to generate cell necrosis during invasive dental procedures, especially in the posterior region of the jaw. There is no consensus about the prevention and treatment of this condition. The aim of this paper is to present a review of the literature with the main characteristics of osteonecrosis of the jaws associated with drugs, together with a proposal for prevention and treatment for these patients.
publisher Sociedad Médica de Santiago
publishDate 2020
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000700983
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