Comparison of pupil diameter and tear production in dogs treated with acepromazine, tramadol and their combination
Some ophthalmic surgeries require induction of mydriasis, however, drugs traditionally used for this purpose significantly reduces tear production. To evaluate the effect of acepromazine and tramadol, used alone or in combination, on pupil diameter, tear production, heart and respiratory rate, systolic blood pressure and rectal temperature, these drugs were administered to seven clinically normal dogs divided into three experimental groups (G1 - acepromazine; G2 - tramadol; G3 - tramadol + acepromazine) that differed only in the sedation protocol. Parameters were measured in four experimental moments. Miosis occurred in G1, in addition to reduced tear production and respiratory rate. No significant changes were found in the parameters assessed in G2, whereas in G3, there was decrease in tear production of the right eye, decrease in the respiratory rate and rectal temperature. Tramadol proved to be a drug suitable for pre-anesthetic procedures that require the maintenance of pupil diameter and keeps the tear production within normal parameters. However, the use of acepromazine alone or in combination with tramadol requires protection of the patient's eye surface to prevent the occurrence of undesirable ophthalmic changes.
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Universidade Federal de Viçosa
2013
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oai:scielo:S0034-737X20130002000042013-05-23Comparison of pupil diameter and tear production in dogs treated with acepromazine, tramadol and their combinationSantos,Paulo Henrique de AlbuquerquePontes,Kelly Cristine de SousaPinto,RogérioRios,Paula Baêta da SilvaSilva,Gláucia Matos Marques daBorges,Andréa Pacheco BatistaFavarato,Lukiya Silva Campos phenothiazines mydriasis Schirmer tear test opioids Some ophthalmic surgeries require induction of mydriasis, however, drugs traditionally used for this purpose significantly reduces tear production. To evaluate the effect of acepromazine and tramadol, used alone or in combination, on pupil diameter, tear production, heart and respiratory rate, systolic blood pressure and rectal temperature, these drugs were administered to seven clinically normal dogs divided into three experimental groups (G1 - acepromazine; G2 - tramadol; G3 - tramadol + acepromazine) that differed only in the sedation protocol. Parameters were measured in four experimental moments. Miosis occurred in G1, in addition to reduced tear production and respiratory rate. No significant changes were found in the parameters assessed in G2, whereas in G3, there was decrease in tear production of the right eye, decrease in the respiratory rate and rectal temperature. Tramadol proved to be a drug suitable for pre-anesthetic procedures that require the maintenance of pupil diameter and keeps the tear production within normal parameters. However, the use of acepromazine alone or in combination with tramadol requires protection of the patient's eye surface to prevent the occurrence of undesirable ophthalmic changes.info:eu-repo/semantics/openAccessUniversidade Federal de ViçosaRevista Ceres v.60 n.2 20132013-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-737X2013000200004en10.1590/S0034-737X2013000200004 |
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Santos,Paulo Henrique de Albuquerque Pontes,Kelly Cristine de Sousa Pinto,Rogério Rios,Paula Baêta da Silva Silva,Gláucia Matos Marques da Borges,Andréa Pacheco Batista Favarato,Lukiya Silva Campos |
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Santos,Paulo Henrique de Albuquerque Pontes,Kelly Cristine de Sousa Pinto,Rogério Rios,Paula Baêta da Silva Silva,Gláucia Matos Marques da Borges,Andréa Pacheco Batista Favarato,Lukiya Silva Campos Comparison of pupil diameter and tear production in dogs treated with acepromazine, tramadol and their combination |
author_facet |
Santos,Paulo Henrique de Albuquerque Pontes,Kelly Cristine de Sousa Pinto,Rogério Rios,Paula Baêta da Silva Silva,Gláucia Matos Marques da Borges,Andréa Pacheco Batista Favarato,Lukiya Silva Campos |
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Santos,Paulo Henrique de Albuquerque |
title |
Comparison of pupil diameter and tear production in dogs treated with acepromazine, tramadol and their combination |
title_short |
Comparison of pupil diameter and tear production in dogs treated with acepromazine, tramadol and their combination |
title_full |
Comparison of pupil diameter and tear production in dogs treated with acepromazine, tramadol and their combination |
title_fullStr |
Comparison of pupil diameter and tear production in dogs treated with acepromazine, tramadol and their combination |
title_full_unstemmed |
Comparison of pupil diameter and tear production in dogs treated with acepromazine, tramadol and their combination |
title_sort |
comparison of pupil diameter and tear production in dogs treated with acepromazine, tramadol and their combination |
description |
Some ophthalmic surgeries require induction of mydriasis, however, drugs traditionally used for this purpose significantly reduces tear production. To evaluate the effect of acepromazine and tramadol, used alone or in combination, on pupil diameter, tear production, heart and respiratory rate, systolic blood pressure and rectal temperature, these drugs were administered to seven clinically normal dogs divided into three experimental groups (G1 - acepromazine; G2 - tramadol; G3 - tramadol + acepromazine) that differed only in the sedation protocol. Parameters were measured in four experimental moments. Miosis occurred in G1, in addition to reduced tear production and respiratory rate. No significant changes were found in the parameters assessed in G2, whereas in G3, there was decrease in tear production of the right eye, decrease in the respiratory rate and rectal temperature. Tramadol proved to be a drug suitable for pre-anesthetic procedures that require the maintenance of pupil diameter and keeps the tear production within normal parameters. However, the use of acepromazine alone or in combination with tramadol requires protection of the patient's eye surface to prevent the occurrence of undesirable ophthalmic changes. |
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Universidade Federal de Viçosa |
publishDate |
2013 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0034-737X2013000200004 |
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