Cerebral hemodynamic and metabolic changes in fulminant hepatic failure

Cerebral hemodynamic and metabolic changes in fulminant hepatic failure

ABSTRACT Intracranial hypertension and brain swelling are a major cause of morbidity and mortality of patients suffering from fulminant hepatic failure (FHF). The pathogenesis of these complications has been investigated in man, in experimental models and in isolated cell systems. Currently, the mechanism underlying cerebral edema and intracranial hypertension in the presence of FHF is multi-factorial in etiology and only partially understood. The aim of this paper is to review the pathophysiology of cerebral hemodynamic and metabolism changes in FHF in order to improve understanding of intracranial dynamics complication in FHF.

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Main Authors: Paschoal Junior,Fernando Mendes, Nogueira,Ricardo de Carvalho, Oliveira,Marcelo de Lima, Paschoal,Eric Homero Albuquerque, Teixeira,Manoel Jacobsen, D’Albuquerque,Luiz Augusto Carneiro, Bor-Seng-Shu,Edson
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2017
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700470
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spelling oai:scielo:S0004-282X20170007004702018-04-02Cerebral hemodynamic and metabolic changes in fulminant hepatic failurePaschoal Junior,Fernando MendesNogueira,Ricardo de CarvalhoOliveira,Marcelo de LimaPaschoal,Eric Homero AlbuquerqueTeixeira,Manoel JacobsenD’Albuquerque,Luiz Augusto CarneiroBor-Seng-Shu,Edson hepatic insufficiency intracranial hypertension brain edema ABSTRACT Intracranial hypertension and brain swelling are a major cause of morbidity and mortality of patients suffering from fulminant hepatic failure (FHF). The pathogenesis of these complications has been investigated in man, in experimental models and in isolated cell systems. Currently, the mechanism underlying cerebral edema and intracranial hypertension in the presence of FHF is multi-factorial in etiology and only partially understood. The aim of this paper is to review the pathophysiology of cerebral hemodynamic and metabolism changes in FHF in order to improve understanding of intracranial dynamics complication in FHF.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.75 n.7 20172017-07-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700470en10.1590/0004-282x20170076
institution SCIELO
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country Brasil
countrycode BR
component Revista
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Paschoal Junior,Fernando Mendes
Nogueira,Ricardo de Carvalho
Oliveira,Marcelo de Lima
Paschoal,Eric Homero Albuquerque
Teixeira,Manoel Jacobsen
D’Albuquerque,Luiz Augusto Carneiro
Bor-Seng-Shu,Edson
spellingShingle Paschoal Junior,Fernando Mendes
Nogueira,Ricardo de Carvalho
Oliveira,Marcelo de Lima
Paschoal,Eric Homero Albuquerque
Teixeira,Manoel Jacobsen
D’Albuquerque,Luiz Augusto Carneiro
Bor-Seng-Shu,Edson
Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
author_facet Paschoal Junior,Fernando Mendes
Nogueira,Ricardo de Carvalho
Oliveira,Marcelo de Lima
Paschoal,Eric Homero Albuquerque
Teixeira,Manoel Jacobsen
D’Albuquerque,Luiz Augusto Carneiro
Bor-Seng-Shu,Edson
author_sort Paschoal Junior,Fernando Mendes
title Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title_short Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title_full Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title_fullStr Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title_full_unstemmed Cerebral hemodynamic and metabolic changes in fulminant hepatic failure
title_sort cerebral hemodynamic and metabolic changes in fulminant hepatic failure
description ABSTRACT Intracranial hypertension and brain swelling are a major cause of morbidity and mortality of patients suffering from fulminant hepatic failure (FHF). The pathogenesis of these complications has been investigated in man, in experimental models and in isolated cell systems. Currently, the mechanism underlying cerebral edema and intracranial hypertension in the presence of FHF is multi-factorial in etiology and only partially understood. The aim of this paper is to review the pathophysiology of cerebral hemodynamic and metabolism changes in FHF in order to improve understanding of intracranial dynamics complication in FHF.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 2017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000700470
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AT oliveiramarcelodelima cerebralhemodynamicandmetabolicchangesinfulminanthepaticfailure
AT paschoalerichomeroalbuquerque cerebralhemodynamicandmetabolicchangesinfulminanthepaticfailure
AT teixeiramanoeljacobsen cerebralhemodynamicandmetabolicchangesinfulminanthepaticfailure
AT dalbuquerqueluizaugustocarneiro cerebralhemodynamicandmetabolicchangesinfulminanthepaticfailure
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