Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study
Objective To assess the effect of aerobic exercise on the cognition and functional capacity in Alzheimer’s disease (AD) patients. Method Elderly (n=20) with mild dementia (NINCDS-ADRDA/CDR1) were randomly assigned to an exercise group (EG) on a treadmill (30 minutes, twice a week and moderate intensity of 60% VO2max) and control group (GC) 10 patients. The primary outcome measure was the cognitive function using Cambridge Cognitive Examination (CAMCOG). Specifics instruments were also applied to evaluate executive function, memory, attention and concentration, cognitive flexibility, inhibitory control and functional capacity. Results After 16 weeks, the EG showed improvement in cognition CAMCOG whereas the CG declined. Compared to the CG, the EG presented significant improvement on the functional capacity. The analysis of the effect size has shown a favorable response to the physical exercise in all dependent variables. Conclusion Walking on treadmill may be recommended as an augmentation treatment for patients with AD.
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Academia Brasileira de Neurologia - ABNEURO
2014
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oai:scielo:S0004-282X20140003001902014-03-28Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled studyArcoverde,CynthiaDeslandes,AndreaMoraes,HelenaAlmeida,CloyraAraujo,Narahyana Bom deVasques,Paulo EduardoSilveira,HeitorLaks,Jerson Alzheimer?s disease aerobic exercise physical training cognitive function functional capacity Objective To assess the effect of aerobic exercise on the cognition and functional capacity in Alzheimer’s disease (AD) patients. Method Elderly (n=20) with mild dementia (NINCDS-ADRDA/CDR1) were randomly assigned to an exercise group (EG) on a treadmill (30 minutes, twice a week and moderate intensity of 60% VO2max) and control group (GC) 10 patients. The primary outcome measure was the cognitive function using Cambridge Cognitive Examination (CAMCOG). Specifics instruments were also applied to evaluate executive function, memory, attention and concentration, cognitive flexibility, inhibitory control and functional capacity. Results After 16 weeks, the EG showed improvement in cognition CAMCOG whereas the CG declined. Compared to the CG, the EG presented significant improvement on the functional capacity. The analysis of the effect size has shown a favorable response to the physical exercise in all dependent variables. Conclusion Walking on treadmill may be recommended as an augmentation treatment for patients with AD. info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.72 n.3 20142014-03-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000300190en10.1590/0004-282X20130231 |
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Arcoverde,Cynthia Deslandes,Andrea Moraes,Helena Almeida,Cloyra Araujo,Narahyana Bom de Vasques,Paulo Eduardo Silveira,Heitor Laks,Jerson |
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Arcoverde,Cynthia Deslandes,Andrea Moraes,Helena Almeida,Cloyra Araujo,Narahyana Bom de Vasques,Paulo Eduardo Silveira,Heitor Laks,Jerson Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
author_facet |
Arcoverde,Cynthia Deslandes,Andrea Moraes,Helena Almeida,Cloyra Araujo,Narahyana Bom de Vasques,Paulo Eduardo Silveira,Heitor Laks,Jerson |
author_sort |
Arcoverde,Cynthia |
title |
Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
title_short |
Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
title_full |
Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
title_fullStr |
Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
title_full_unstemmed |
Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study |
title_sort |
treadmill training as an augmentation treatment for alzheimer?s disease: a pilot randomized controlled study |
description |
Objective To assess the effect of aerobic exercise on the cognition and functional capacity in Alzheimer’s disease (AD) patients. Method Elderly (n=20) with mild dementia (NINCDS-ADRDA/CDR1) were randomly assigned to an exercise group (EG) on a treadmill (30 minutes, twice a week and moderate intensity of 60% VO2max) and control group (GC) 10 patients. The primary outcome measure was the cognitive function using Cambridge Cognitive Examination (CAMCOG). Specifics instruments were also applied to evaluate executive function, memory, attention and concentration, cognitive flexibility, inhibitory control and functional capacity. Results After 16 weeks, the EG showed improvement in cognition CAMCOG whereas the CG declined. Compared to the CG, the EG presented significant improvement on the functional capacity. The analysis of the effect size has shown a favorable response to the physical exercise in all dependent variables. Conclusion Walking on treadmill may be recommended as an augmentation treatment for patients with AD. |
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Academia Brasileira de Neurologia - ABNEURO |
publishDate |
2014 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000300190 |
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