Invasive medullary thymoma associated with myasthenia gravis: an unusual case

Thymomas are tumors characterized by a remarkable morphological heterogeneity and variable clinical behavior. This tumor has unique clinical associations, most notably with hematological abnormalities and myasthenia gravis. According with the Müller-Hermelink criteria, there are significant differences between the histological types of thymomas and the association with myasthenia gravis. Among the different histological types, medullary thymoma is the least frequent variant associated with this autoimmune disease. In this report we describe a case of medullary thymoma presenting in a 71-year- old woman with a myasthenic syndrome.

Saved in:
Bibliographic Details
Main Authors: REIS FILHO,JORGE S., MILANEZI,MARIA FERNANDA, MOREIRA,CHRISTIANO G., WERNECK,LINEU C., BOSCARDIN,PAULO, IOSHII,SERGIO OSSAMU, SCHMITT,FERNANDO C.
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia - ABNEURO 2000
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000600020
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:scielo:S0004-282X2000000600020
record_format ojs
spelling oai:scielo:S0004-282X20000006000202000-12-01Invasive medullary thymoma associated with myasthenia gravis: an unusual caseREIS FILHO,JORGE S.MILANEZI,MARIA FERNANDAMOREIRA,CHRISTIANO G.WERNECK,LINEU C.BOSCARDIN,PAULOIOSHII,SERGIO OSSAMUSCHMITT,FERNANDO C. medullary thymoma myasthenia gravis immunohistochemistry Müller-Hermelink classification Thymomas are tumors characterized by a remarkable morphological heterogeneity and variable clinical behavior. This tumor has unique clinical associations, most notably with hematological abnormalities and myasthenia gravis. According with the Müller-Hermelink criteria, there are significant differences between the histological types of thymomas and the association with myasthenia gravis. Among the different histological types, medullary thymoma is the least frequent variant associated with this autoimmune disease. In this report we describe a case of medullary thymoma presenting in a 71-year- old woman with a myasthenic syndrome.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia - ABNEUROArquivos de Neuro-Psiquiatria v.58 n.4 20002000-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000600020en10.1590/S0004-282X2000000600020
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author REIS FILHO,JORGE S.
MILANEZI,MARIA FERNANDA
MOREIRA,CHRISTIANO G.
WERNECK,LINEU C.
BOSCARDIN,PAULO
IOSHII,SERGIO OSSAMU
SCHMITT,FERNANDO C.
spellingShingle REIS FILHO,JORGE S.
MILANEZI,MARIA FERNANDA
MOREIRA,CHRISTIANO G.
WERNECK,LINEU C.
BOSCARDIN,PAULO
IOSHII,SERGIO OSSAMU
SCHMITT,FERNANDO C.
Invasive medullary thymoma associated with myasthenia gravis: an unusual case
author_facet REIS FILHO,JORGE S.
MILANEZI,MARIA FERNANDA
MOREIRA,CHRISTIANO G.
WERNECK,LINEU C.
BOSCARDIN,PAULO
IOSHII,SERGIO OSSAMU
SCHMITT,FERNANDO C.
author_sort REIS FILHO,JORGE S.
title Invasive medullary thymoma associated with myasthenia gravis: an unusual case
title_short Invasive medullary thymoma associated with myasthenia gravis: an unusual case
title_full Invasive medullary thymoma associated with myasthenia gravis: an unusual case
title_fullStr Invasive medullary thymoma associated with myasthenia gravis: an unusual case
title_full_unstemmed Invasive medullary thymoma associated with myasthenia gravis: an unusual case
title_sort invasive medullary thymoma associated with myasthenia gravis: an unusual case
description Thymomas are tumors characterized by a remarkable morphological heterogeneity and variable clinical behavior. This tumor has unique clinical associations, most notably with hematological abnormalities and myasthenia gravis. According with the Müller-Hermelink criteria, there are significant differences between the histological types of thymomas and the association with myasthenia gravis. Among the different histological types, medullary thymoma is the least frequent variant associated with this autoimmune disease. In this report we describe a case of medullary thymoma presenting in a 71-year- old woman with a myasthenic syndrome.
publisher Academia Brasileira de Neurologia - ABNEURO
publishDate 2000
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2000000600020
work_keys_str_mv AT reisfilhojorges invasivemedullarythymomaassociatedwithmyastheniagravisanunusualcase
AT milanezimariafernanda invasivemedullarythymomaassociatedwithmyastheniagravisanunusualcase
AT moreirachristianog invasivemedullarythymomaassociatedwithmyastheniagravisanunusualcase
AT wernecklineuc invasivemedullarythymomaassociatedwithmyastheniagravisanunusualcase
AT boscardinpaulo invasivemedullarythymomaassociatedwithmyastheniagravisanunusualcase
AT ioshiisergioossamu invasivemedullarythymomaassociatedwithmyastheniagravisanunusualcase
AT schmittfernandoc invasivemedullarythymomaassociatedwithmyastheniagravisanunusualcase
_version_ 1756374160147218432