Analysis of corneal esthesia in patients undergoing photorefractive keratectomy

ABSTRACT Purpose: To quantitatively analyze corneal esthesia in patients undergoing photorefractive keratectomy (PRK) surgery. Methods: Forty-five patients selected for PRK in one eye underwent corneal esthesia using a Cochet-Bonnet esthesiometer preoperatively and 30 and 90 days postoperatively. Patients with a refractive diopter error of 4 or greater received intraoperative 0.02% mitomycin C for 20 s. Results: Twenty-four (53.3%) of the 45 eyes received intraoperative 0.02% mitomycin. Decreased sensitivity was observed on postoperative day 30. By postoperative day 90, corneal esthesia had normalized but remained 14.9% lower than preoperative levels. In the mitomycin group, no recovery of corneal esthesia to normal sensitivity levels was observed. The mean esthesiometer level was 39.2 mm on postoperative day 90 (P<0.001). Conclusions: The results of the present study demonstrate recovery of corneal esthesia to normal levels at 90 days postoperatively in patients who did not receive mitomycin C. In patients administered mitomycin C, a 23.59% reduction in the corneal touch threshold was observed compared with preoperative levels indicating a failure of recovery to normal levels.

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Main Authors: Torres Neto,Elmar, Silva,Lucas Marcel Amaral, Lui,Giovana Arlene Fioravanti, Gomes,Rachel Lopes Rodrigues, Lui-Netto,Adamo
Format: Digital revista
Language:English
Published: Conselho Brasileiro de Oftalmologia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000600363
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spelling oai:scielo:S0004-274920150006003632015-12-09Analysis of corneal esthesia in patients undergoing photorefractive keratectomyTorres Neto,ElmarSilva,Lucas Marcel AmaralLui,Giovana Arlene FioravantiGomes,Rachel Lopes RodriguesLui-Netto,Adamo Mitomycin Cornea Photorefractive keratectomy Myopia Prospective studies ABSTRACT Purpose: To quantitatively analyze corneal esthesia in patients undergoing photorefractive keratectomy (PRK) surgery. Methods: Forty-five patients selected for PRK in one eye underwent corneal esthesia using a Cochet-Bonnet esthesiometer preoperatively and 30 and 90 days postoperatively. Patients with a refractive diopter error of 4 or greater received intraoperative 0.02% mitomycin C for 20 s. Results: Twenty-four (53.3%) of the 45 eyes received intraoperative 0.02% mitomycin. Decreased sensitivity was observed on postoperative day 30. By postoperative day 90, corneal esthesia had normalized but remained 14.9% lower than preoperative levels. In the mitomycin group, no recovery of corneal esthesia to normal sensitivity levels was observed. The mean esthesiometer level was 39.2 mm on postoperative day 90 (P<0.001). Conclusions: The results of the present study demonstrate recovery of corneal esthesia to normal levels at 90 days postoperatively in patients who did not receive mitomycin C. In patients administered mitomycin C, a 23.59% reduction in the corneal touch threshold was observed compared with preoperative levels indicating a failure of recovery to normal levels.info:eu-repo/semantics/openAccessConselho Brasileiro de OftalmologiaArquivos Brasileiros de Oftalmologia v.78 n.6 20152015-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000600363en10.5935/0004-2749.20150096
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countrycode BR
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Torres Neto,Elmar
Silva,Lucas Marcel Amaral
Lui,Giovana Arlene Fioravanti
Gomes,Rachel Lopes Rodrigues
Lui-Netto,Adamo
spellingShingle Torres Neto,Elmar
Silva,Lucas Marcel Amaral
Lui,Giovana Arlene Fioravanti
Gomes,Rachel Lopes Rodrigues
Lui-Netto,Adamo
Analysis of corneal esthesia in patients undergoing photorefractive keratectomy
author_facet Torres Neto,Elmar
Silva,Lucas Marcel Amaral
Lui,Giovana Arlene Fioravanti
Gomes,Rachel Lopes Rodrigues
Lui-Netto,Adamo
author_sort Torres Neto,Elmar
title Analysis of corneal esthesia in patients undergoing photorefractive keratectomy
title_short Analysis of corneal esthesia in patients undergoing photorefractive keratectomy
title_full Analysis of corneal esthesia in patients undergoing photorefractive keratectomy
title_fullStr Analysis of corneal esthesia in patients undergoing photorefractive keratectomy
title_full_unstemmed Analysis of corneal esthesia in patients undergoing photorefractive keratectomy
title_sort analysis of corneal esthesia in patients undergoing photorefractive keratectomy
description ABSTRACT Purpose: To quantitatively analyze corneal esthesia in patients undergoing photorefractive keratectomy (PRK) surgery. Methods: Forty-five patients selected for PRK in one eye underwent corneal esthesia using a Cochet-Bonnet esthesiometer preoperatively and 30 and 90 days postoperatively. Patients with a refractive diopter error of 4 or greater received intraoperative 0.02% mitomycin C for 20 s. Results: Twenty-four (53.3%) of the 45 eyes received intraoperative 0.02% mitomycin. Decreased sensitivity was observed on postoperative day 30. By postoperative day 90, corneal esthesia had normalized but remained 14.9% lower than preoperative levels. In the mitomycin group, no recovery of corneal esthesia to normal sensitivity levels was observed. The mean esthesiometer level was 39.2 mm on postoperative day 90 (P<0.001). Conclusions: The results of the present study demonstrate recovery of corneal esthesia to normal levels at 90 days postoperatively in patients who did not receive mitomycin C. In patients administered mitomycin C, a 23.59% reduction in the corneal touch threshold was observed compared with preoperative levels indicating a failure of recovery to normal levels.
publisher Conselho Brasileiro de Oftalmologia
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492015000600363
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