Matrix metalloproteinase-9 expression in pterygium

PURPOSE: To assess matrix metalloproteinase (MMP)-9 expression in pterygium lesion. METHODS: A prospective randomized clinical trial was done to evaluate the expression of matrix metalloproteinase in normal and in primary or recurrent pterygia in Tenon's capsule by immunohistochemical analysis and a computerized image analysis system. The data were submitted to statistical analysis. RESULTS: Matrix metalloproteinase expression showed no difference in normal Tenon's capsule and in primary or recurrent pterygia. CONCLUSION: The similar expression of the matrix metalloproteinase in normal Tenon's capsule and in primary or recurrent pterygia allowed us to conclude that matrix metalloproteinase is not implicated in the genesis or the recurrence of pterygium lesion.

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Main Authors: Schellini,Silvana Artioli, Hoyama,Erika, Oliveira,Deilson Elgui, Bacchi,Carlos Eduardo, Padovani,Carlos Roberto
Format: Digital revista
Language:English
Published: Conselho Brasileiro de Oftalmologia 2006
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492006000200005
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spelling oai:scielo:S0004-274920060002000052006-09-29Matrix metalloproteinase-9 expression in pterygiumSchellini,Silvana ArtioliHoyama,ErikaOliveira,Deilson ElguiBacchi,Carlos EduardoPadovani,Carlos Roberto Pterygium Matrix metalloproteinases Immunohistochemical/methods Recurrence PURPOSE: To assess matrix metalloproteinase (MMP)-9 expression in pterygium lesion. METHODS: A prospective randomized clinical trial was done to evaluate the expression of matrix metalloproteinase in normal and in primary or recurrent pterygia in Tenon's capsule by immunohistochemical analysis and a computerized image analysis system. The data were submitted to statistical analysis. RESULTS: Matrix metalloproteinase expression showed no difference in normal Tenon's capsule and in primary or recurrent pterygia. CONCLUSION: The similar expression of the matrix metalloproteinase in normal Tenon's capsule and in primary or recurrent pterygia allowed us to conclude that matrix metalloproteinase is not implicated in the genesis or the recurrence of pterygium lesion.info:eu-repo/semantics/openAccessConselho Brasileiro de OftalmologiaArquivos Brasileiros de Oftalmologia v.69 n.2 20062006-04-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492006000200005en10.1590/S0004-27492006000200005
institution SCIELO
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country Brasil
countrycode BR
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region America del Sur
libraryname SciELO
language English
format Digital
author Schellini,Silvana Artioli
Hoyama,Erika
Oliveira,Deilson Elgui
Bacchi,Carlos Eduardo
Padovani,Carlos Roberto
spellingShingle Schellini,Silvana Artioli
Hoyama,Erika
Oliveira,Deilson Elgui
Bacchi,Carlos Eduardo
Padovani,Carlos Roberto
Matrix metalloproteinase-9 expression in pterygium
author_facet Schellini,Silvana Artioli
Hoyama,Erika
Oliveira,Deilson Elgui
Bacchi,Carlos Eduardo
Padovani,Carlos Roberto
author_sort Schellini,Silvana Artioli
title Matrix metalloproteinase-9 expression in pterygium
title_short Matrix metalloproteinase-9 expression in pterygium
title_full Matrix metalloproteinase-9 expression in pterygium
title_fullStr Matrix metalloproteinase-9 expression in pterygium
title_full_unstemmed Matrix metalloproteinase-9 expression in pterygium
title_sort matrix metalloproteinase-9 expression in pterygium
description PURPOSE: To assess matrix metalloproteinase (MMP)-9 expression in pterygium lesion. METHODS: A prospective randomized clinical trial was done to evaluate the expression of matrix metalloproteinase in normal and in primary or recurrent pterygia in Tenon's capsule by immunohistochemical analysis and a computerized image analysis system. The data were submitted to statistical analysis. RESULTS: Matrix metalloproteinase expression showed no difference in normal Tenon's capsule and in primary or recurrent pterygia. CONCLUSION: The similar expression of the matrix metalloproteinase in normal Tenon's capsule and in primary or recurrent pterygia allowed us to conclude that matrix metalloproteinase is not implicated in the genesis or the recurrence of pterygium lesion.
publisher Conselho Brasileiro de Oftalmologia
publishDate 2006
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0004-27492006000200005
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AT oliveiradeilsonelgui matrixmetalloproteinase9expressioninpterygium
AT bacchicarloseduardo matrixmetalloproteinase9expressioninpterygium
AT padovanicarlosroberto matrixmetalloproteinase9expressioninpterygium
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