Effect of developmental and ancestral high-altitude exposure on chest morphology and pulmonary function in andean and european/north american natives
Abstract. Chest depth, chest width, forced vital capacity (FVC), and forced expiratory volume (FEV1) were measured in 170 adult males differing by ancestral (genetic) and developmental exposure to high altitude (HA). A complete migrant study design was used to study HA natives (Aymara/Quechua ancestry, n = 88) and low altitude (LA) natives (European/North American ancestry, n = 82) at both altitude (La Paz, Bolivia, 3,600 m) and near sea level (Santa Cruz, Bolivia, 420 m). HAN and LAN migrant groups were classified as: Nth generation migrants, born and raised in a non-native environment; child migrants who migrated during the period of growth and maturation (0–18 yrs); and adult migrants who migrated after 18 years of age. Chest depth, FVC, and FEV1 measures were larger with increasing developmental exposure in both HAN migrants at LA and LAN migrants at HA. Developmental responses were similar between HAN and LAN groups. FVC and FEV1 measures were larger in HANs vs LANs born and raised at HA to suggest a genetic effect, but were similar in HANs and LANs born and raised at LA. The similarity of HAN and LAN groups at LA suggests that the genetic potential for larger lung volumes at HA depends upon developmental exposure to HA. Additional data for females (HANs at HA, n = 20, and LAN adult migrants to HA, n = 17) show similar differences as those shown between male HAN and LAN groups. Am. J. Hum. Biol. 11:383–395, 1999. © 1999 Wiley-Liss, Inc.
Main Authors: | , , , , |
---|---|
Format: | Article biblioteca |
Language: | English |
Published: |
American Journal of Human Biology
1999
|
Subjects: | MORFOLOGÍA DEL TÓRAX, FUNCIÓN PULMONAR, ALTURA, ANDINOS, EUROPEOS, |
Online Access: | http://repositorio.umsa.bo/xmlui/handle/123456789/25059 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:localhost:8080:123456789-25059 |
---|---|
record_format |
koha |
spelling |
oai:localhost:8080:123456789-250592021-05-06T14:44:51Z Effect of developmental and ancestral high-altitude exposure on chest morphology and pulmonary function in andean and european/north american natives Brutsaert, Tom D Soria, Rudy Cáceres, Esperanza Spielvogel, Hilde Haas, Jere D MORFOLOGÍA DEL TÓRAX FUNCIÓN PULMONAR ALTURA ANDINOS EUROPEOS Abstract. Chest depth, chest width, forced vital capacity (FVC), and forced expiratory volume (FEV1) were measured in 170 adult males differing by ancestral (genetic) and developmental exposure to high altitude (HA). A complete migrant study design was used to study HA natives (Aymara/Quechua ancestry, n = 88) and low altitude (LA) natives (European/North American ancestry, n = 82) at both altitude (La Paz, Bolivia, 3,600 m) and near sea level (Santa Cruz, Bolivia, 420 m). HAN and LAN migrant groups were classified as: Nth generation migrants, born and raised in a non-native environment; child migrants who migrated during the period of growth and maturation (0–18 yrs); and adult migrants who migrated after 18 years of age. Chest depth, FVC, and FEV1 measures were larger with increasing developmental exposure in both HAN migrants at LA and LAN migrants at HA. Developmental responses were similar between HAN and LAN groups. FVC and FEV1 measures were larger in HANs vs LANs born and raised at HA to suggest a genetic effect, but were similar in HANs and LANs born and raised at LA. The similarity of HAN and LAN groups at LA suggests that the genetic potential for larger lung volumes at HA depends upon developmental exposure to HA. Additional data for females (HANs at HA, n = 20, and LAN adult migrants to HA, n = 17) show similar differences as those shown between male HAN and LAN groups. Am. J. Hum. Biol. 11:383–395, 1999. © 1999 Wiley-Liss, Inc. 2021-05-06T14:44:51Z 2021-05-06T14:44:51Z 1999 Article http://repositorio.umsa.bo/xmlui/handle/123456789/25059 en application/pdf American Journal of Human Biology |
institution |
UMSA BO |
collection |
DSpace |
country |
Bolivia |
countrycode |
BO |
component |
Bibliográfico |
access |
En linea |
databasecode |
dig-umsa-bo |
tag |
biblioteca |
region |
America del Sur |
libraryname |
Sistema de Unidades de Información de UMSA |
language |
English |
topic |
MORFOLOGÍA DEL TÓRAX FUNCIÓN PULMONAR ALTURA ANDINOS EUROPEOS MORFOLOGÍA DEL TÓRAX FUNCIÓN PULMONAR ALTURA ANDINOS EUROPEOS |
spellingShingle |
MORFOLOGÍA DEL TÓRAX FUNCIÓN PULMONAR ALTURA ANDINOS EUROPEOS MORFOLOGÍA DEL TÓRAX FUNCIÓN PULMONAR ALTURA ANDINOS EUROPEOS Brutsaert, Tom D Soria, Rudy Cáceres, Esperanza Spielvogel, Hilde Haas, Jere D Effect of developmental and ancestral high-altitude exposure on chest morphology and pulmonary function in andean and european/north american natives |
description |
Abstract.
Chest depth, chest width, forced vital capacity (FVC), and forced expiratory volume (FEV1) were measured in 170 adult males differing by ancestral (genetic) and developmental exposure to high altitude (HA). A complete migrant study design was used to study HA natives (Aymara/Quechua ancestry, n = 88) and low altitude (LA) natives (European/North American ancestry, n = 82) at both altitude (La Paz, Bolivia, 3,600 m) and near sea level (Santa Cruz, Bolivia, 420 m). HAN and LAN migrant groups were classified as: Nth generation migrants, born and raised in a non-native environment; child migrants who migrated during the period of growth and maturation (0–18 yrs); and adult migrants who migrated after 18 years of age. Chest depth, FVC, and FEV1 measures were larger with increasing developmental exposure in both HAN migrants at LA and LAN migrants at HA. Developmental responses were similar between HAN and LAN groups. FVC and FEV1 measures were larger in HANs vs LANs born and raised at HA to suggest a genetic effect, but were similar in HANs and LANs born and raised at LA. The similarity of HAN and LAN groups at LA suggests that the genetic potential for larger lung volumes at HA depends upon developmental exposure to HA. Additional data for females (HANs at HA, n = 20, and LAN adult migrants to HA, n = 17) show similar differences as those shown between male HAN and LAN groups. Am. J. Hum. Biol. 11:383–395, 1999. © 1999 Wiley-Liss, Inc. |
format |
Article |
topic_facet |
MORFOLOGÍA DEL TÓRAX FUNCIÓN PULMONAR ALTURA ANDINOS EUROPEOS |
author |
Brutsaert, Tom D Soria, Rudy Cáceres, Esperanza Spielvogel, Hilde Haas, Jere D |
author_facet |
Brutsaert, Tom D Soria, Rudy Cáceres, Esperanza Spielvogel, Hilde Haas, Jere D |
author_sort |
Brutsaert, Tom D |
title |
Effect of developmental and ancestral high-altitude exposure on chest morphology and pulmonary function in andean and european/north american natives |
title_short |
Effect of developmental and ancestral high-altitude exposure on chest morphology and pulmonary function in andean and european/north american natives |
title_full |
Effect of developmental and ancestral high-altitude exposure on chest morphology and pulmonary function in andean and european/north american natives |
title_fullStr |
Effect of developmental and ancestral high-altitude exposure on chest morphology and pulmonary function in andean and european/north american natives |
title_full_unstemmed |
Effect of developmental and ancestral high-altitude exposure on chest morphology and pulmonary function in andean and european/north american natives |
title_sort |
effect of developmental and ancestral high-altitude exposure on chest morphology and pulmonary function in andean and european/north american natives |
publisher |
American Journal of Human Biology |
publishDate |
1999 |
url |
http://repositorio.umsa.bo/xmlui/handle/123456789/25059 |
work_keys_str_mv |
AT brutsaerttomd effectofdevelopmentalandancestralhighaltitudeexposureonchestmorphologyandpulmonaryfunctioninandeanandeuropeannorthamericannatives AT soriarudy effectofdevelopmentalandancestralhighaltitudeexposureonchestmorphologyandpulmonaryfunctioninandeanandeuropeannorthamericannatives AT caceresesperanza effectofdevelopmentalandancestralhighaltitudeexposureonchestmorphologyandpulmonaryfunctioninandeanandeuropeannorthamericannatives AT spielvogelhilde effectofdevelopmentalandancestralhighaltitudeexposureonchestmorphologyandpulmonaryfunctioninandeanandeuropeannorthamericannatives AT haasjered effectofdevelopmentalandancestralhighaltitudeexposureonchestmorphologyandpulmonaryfunctioninandeanandeuropeannorthamericannatives |
_version_ |
1766394841333235712 |