Development of a reproducible small intestinal microbiota model and its integration into the SHIME-system, a dynamic in vitro gut model

Development of a reproducible small intestinal microbiota model and its integration into the SHIME-system, a dynamic in vitro gut model

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The human gastrointestinal tract consists of different regions, each characterized by a distinct physiology, anatomy, and microbial community. While the colonic microbiota has received a lot of attention in recent research projects, little is known about the small intestinal microbiota and its interactions with ingested compounds, primarily due to the inaccessibility of this region in vivo. This study therefore aimed to develop and validate a dynamic, long-term simulation of the ileal microbiota using the SHIME-technology.

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Bibliographic Details
Main Authors: Deyaert, Stef, Moens, Frédéric, Pirovano, Walter, van den Bogert, Bartholomeus, Klaassens, Eline Suzanne, Marzorati, Massimo, Van de Wiele, Tom, Kleerebezem, Michiel, Van den Abbeele, Pieter
Format: Dataset biblioteca
Published: PROMISE
Subjects:Human gastrointestinal tract, SHIME-technology, microbiota,
Online Access:https://research.wur.nl/en/datasets/development-of-a-reproducible-small-intestinal-microbiota-model-a
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id dig-wur-nl-wurpubs-636397
record_format koha
spelling dig-wur-nl-wurpubs-6363972024-10-28 Deyaert, Stef Moens, Frédéric Pirovano, Walter van den Bogert, Bartholomeus Klaassens, Eline Suzanne Marzorati, Massimo Van de Wiele, Tom Kleerebezem, Michiel Van den Abbeele, Pieter Dataset Development of a reproducible small intestinal microbiota model and its integration into the SHIME-system, a dynamic in vitro gut model 2023 The human gastrointestinal tract consists of different regions, each characterized by a distinct physiology, anatomy, and microbial community. While the colonic microbiota has received a lot of attention in recent research projects, little is known about the small intestinal microbiota and its interactions with ingested compounds, primarily due to the inaccessibility of this region in vivo. This study therefore aimed to develop and validate a dynamic, long-term simulation of the ileal microbiota using the SHIME-technology. PROMISE text/html https://research.wur.nl/en/datasets/development-of-a-reproducible-small-intestinal-microbiota-model-a https://edepot.wur.nl/676661 Human gastrointestinal tract SHIME-technology microbiota Wageningen University & Research
institution WUR NL
collection DSpace
country Países bajos
countrycode NL
component Bibliográfico
access En linea
databasecode dig-wur-nl
tag biblioteca
region Europa del Oeste
libraryname WUR Library Netherlands
topic Human gastrointestinal tract
SHIME-technology
microbiota
Human gastrointestinal tract
SHIME-technology
microbiota
spellingShingle Human gastrointestinal tract
SHIME-technology
microbiota
Human gastrointestinal tract
SHIME-technology
microbiota
Deyaert, Stef
Moens, Frédéric
Pirovano, Walter
van den Bogert, Bartholomeus
Klaassens, Eline Suzanne
Marzorati, Massimo
Van de Wiele, Tom
Kleerebezem, Michiel
Van den Abbeele, Pieter
Development of a reproducible small intestinal microbiota model and its integration into the SHIME-system, a dynamic in vitro gut model
description The human gastrointestinal tract consists of different regions, each characterized by a distinct physiology, anatomy, and microbial community. While the colonic microbiota has received a lot of attention in recent research projects, little is known about the small intestinal microbiota and its interactions with ingested compounds, primarily due to the inaccessibility of this region in vivo. This study therefore aimed to develop and validate a dynamic, long-term simulation of the ileal microbiota using the SHIME-technology.
format Dataset
topic_facet Human gastrointestinal tract
SHIME-technology
microbiota
author Deyaert, Stef
Moens, Frédéric
Pirovano, Walter
van den Bogert, Bartholomeus
Klaassens, Eline Suzanne
Marzorati, Massimo
Van de Wiele, Tom
Kleerebezem, Michiel
Van den Abbeele, Pieter
author_facet Deyaert, Stef
Moens, Frédéric
Pirovano, Walter
van den Bogert, Bartholomeus
Klaassens, Eline Suzanne
Marzorati, Massimo
Van de Wiele, Tom
Kleerebezem, Michiel
Van den Abbeele, Pieter
author_sort Deyaert, Stef
title Development of a reproducible small intestinal microbiota model and its integration into the SHIME-system, a dynamic in vitro gut model
title_short Development of a reproducible small intestinal microbiota model and its integration into the SHIME-system, a dynamic in vitro gut model
title_full Development of a reproducible small intestinal microbiota model and its integration into the SHIME-system, a dynamic in vitro gut model
title_fullStr Development of a reproducible small intestinal microbiota model and its integration into the SHIME-system, a dynamic in vitro gut model
title_full_unstemmed Development of a reproducible small intestinal microbiota model and its integration into the SHIME-system, a dynamic in vitro gut model
title_sort development of a reproducible small intestinal microbiota model and its integration into the shime-system, a dynamic in vitro gut model
publisher PROMISE
url https://research.wur.nl/en/datasets/development-of-a-reproducible-small-intestinal-microbiota-model-a
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AT marzoratimassimo developmentofareproduciblesmallintestinalmicrobiotamodelanditsintegrationintotheshimesystemadynamicinvitrogutmodel
AT vandewieletom developmentofareproduciblesmallintestinalmicrobiotamodelanditsintegrationintotheshimesystemadynamicinvitrogutmodel
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AT vandenabbeelepieter developmentofareproduciblesmallintestinalmicrobiotamodelanditsintegrationintotheshimesystemadynamicinvitrogutmodel
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