Effects of porcine MC4R and LEPR polymorphisms, gender and Duroc sire line on economic traits in Duroc×Iberian crossbred pigs

Polymorphisms MC4R c.1426A>G (p.Asp298Asn) and LEPR c.2002C>T (p.Leu663Phe) have been associated in pigs with feed intake, growth and fatness. Our aims were to analyze how these polymorphisms influence production and quality traits in Duroc × Iberian crossbred pigs, and moreover evaluate how the effects of gender and Duroc line were affecting these traits. Significant effects of gender, Duroc sire line and LEPR c.2002C>T mutation, were detected on the main traits. LEPR c.2002T allele increased body weight (2.5 ± 0.7. kg), backfat thickness (1.5 ± 0.4. mm), loin intramuscular fat (0.7 ± 0.2 %), and lightness (1.0 ± 0.3); however it was decreasing premium cuts yield (-0.9 ± 0.2%). Allele c.2002T increased SFA (0.60 ± 0.12 %), and decreased MUFA (-0.35 ± 0.12%) and PUFA (-0.25 ± 0.06%). No significant effects of MC4R c.1426A>G SNP were identified. A genetic test based on the LEPR c.2002C>T SNP may be useful to select Duroc sires to reduce undesirable heterogeneity of carcasses and premium cuts of crossbred animals. © 2010 The American Meat Science Association.

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Main Authors: Muñoz, G., Alcázar, E., Fernández, A., Barragán, C., Carrasco, A., de Pedro, E., Silió, L., Sánchez, J. L., Rodríguez, M. C.
Format: journal article biblioteca
Language:English
Published: Elsevier 2011
Subjects:MC4R, LEPR, Meat quality, Heavy pigs, Duroc, Iberian,
Online Access:http://hdl.handle.net/20.500.12792/3047
http://hdl.handle.net/10261/293347
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spelling dig-inia-es-10261-2933472023-02-20T10:27:35Z Effects of porcine MC4R and LEPR polymorphisms, gender and Duroc sire line on economic traits in Duroc×Iberian crossbred pigs Muñoz, G. Alcázar, E. Fernández, A. Barragán, C. Carrasco, A. de Pedro, E. Silió, L. Sánchez, J. L. Rodríguez, M. C. MC4R LEPR Meat quality Heavy pigs Duroc Iberian Polymorphisms MC4R c.1426A>G (p.Asp298Asn) and LEPR c.2002C>T (p.Leu663Phe) have been associated in pigs with feed intake, growth and fatness. Our aims were to analyze how these polymorphisms influence production and quality traits in Duroc × Iberian crossbred pigs, and moreover evaluate how the effects of gender and Duroc line were affecting these traits. Significant effects of gender, Duroc sire line and LEPR c.2002C>T mutation, were detected on the main traits. LEPR c.2002T allele increased body weight (2.5 ± 0.7. kg), backfat thickness (1.5 ± 0.4. mm), loin intramuscular fat (0.7 ± 0.2 %), and lightness (1.0 ± 0.3); however it was decreasing premium cuts yield (-0.9 ± 0.2%). Allele c.2002T increased SFA (0.60 ± 0.12 %), and decreased MUFA (-0.35 ± 0.12%) and PUFA (-0.25 ± 0.06%). No significant effects of MC4R c.1426A>G SNP were identified. A genetic test based on the LEPR c.2002C>T SNP may be useful to select Duroc sires to reduce undesirable heterogeneity of carcasses and premium cuts of crossbred animals. © 2010 The American Meat Science Association. 2023-02-20T10:27:35Z 2023-02-20T10:27:35Z 2011 journal article Meat Science 88(1): 169-173 (2011) 0309-1740 http://hdl.handle.net/20.500.12792/3047 http://hdl.handle.net/10261/293347 10.1016/j.meatsci.2010.12.018 en none Elsevier
institution INIA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-inia-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del INIA España
language English
topic MC4R
LEPR
Meat quality
Heavy pigs
Duroc
Iberian
MC4R
LEPR
Meat quality
Heavy pigs
Duroc
Iberian
spellingShingle MC4R
LEPR
Meat quality
Heavy pigs
Duroc
Iberian
MC4R
LEPR
Meat quality
Heavy pigs
Duroc
Iberian
Muñoz, G.
Alcázar, E.
Fernández, A.
Barragán, C.
Carrasco, A.
de Pedro, E.
Silió, L.
Sánchez, J. L.
Rodríguez, M. C.
Effects of porcine MC4R and LEPR polymorphisms, gender and Duroc sire line on economic traits in Duroc×Iberian crossbred pigs
description Polymorphisms MC4R c.1426A>G (p.Asp298Asn) and LEPR c.2002C>T (p.Leu663Phe) have been associated in pigs with feed intake, growth and fatness. Our aims were to analyze how these polymorphisms influence production and quality traits in Duroc × Iberian crossbred pigs, and moreover evaluate how the effects of gender and Duroc line were affecting these traits. Significant effects of gender, Duroc sire line and LEPR c.2002C>T mutation, were detected on the main traits. LEPR c.2002T allele increased body weight (2.5 ± 0.7. kg), backfat thickness (1.5 ± 0.4. mm), loin intramuscular fat (0.7 ± 0.2 %), and lightness (1.0 ± 0.3); however it was decreasing premium cuts yield (-0.9 ± 0.2%). Allele c.2002T increased SFA (0.60 ± 0.12 %), and decreased MUFA (-0.35 ± 0.12%) and PUFA (-0.25 ± 0.06%). No significant effects of MC4R c.1426A>G SNP were identified. A genetic test based on the LEPR c.2002C>T SNP may be useful to select Duroc sires to reduce undesirable heterogeneity of carcasses and premium cuts of crossbred animals. © 2010 The American Meat Science Association.
format journal article
topic_facet MC4R
LEPR
Meat quality
Heavy pigs
Duroc
Iberian
author Muñoz, G.
Alcázar, E.
Fernández, A.
Barragán, C.
Carrasco, A.
de Pedro, E.
Silió, L.
Sánchez, J. L.
Rodríguez, M. C.
author_facet Muñoz, G.
Alcázar, E.
Fernández, A.
Barragán, C.
Carrasco, A.
de Pedro, E.
Silió, L.
Sánchez, J. L.
Rodríguez, M. C.
author_sort Muñoz, G.
title Effects of porcine MC4R and LEPR polymorphisms, gender and Duroc sire line on economic traits in Duroc×Iberian crossbred pigs
title_short Effects of porcine MC4R and LEPR polymorphisms, gender and Duroc sire line on economic traits in Duroc×Iberian crossbred pigs
title_full Effects of porcine MC4R and LEPR polymorphisms, gender and Duroc sire line on economic traits in Duroc×Iberian crossbred pigs
title_fullStr Effects of porcine MC4R and LEPR polymorphisms, gender and Duroc sire line on economic traits in Duroc×Iberian crossbred pigs
title_full_unstemmed Effects of porcine MC4R and LEPR polymorphisms, gender and Duroc sire line on economic traits in Duroc×Iberian crossbred pigs
title_sort effects of porcine mc4r and lepr polymorphisms, gender and duroc sire line on economic traits in duroc×iberian crossbred pigs
publisher Elsevier
publishDate 2011
url http://hdl.handle.net/20.500.12792/3047
http://hdl.handle.net/10261/293347
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