A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates

A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates

14 Pág. Centro de Investigación en Sanidad Animal (CISA)

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Bibliographic Details
Main Authors: Rojas, José Manuel, Sevilla, Noemí, Martín, Verónica
Other Authors: Ministerio de Ciencia e Innovación (España)
Format: artículo biblioteca
Language:English
Published: Frontiers Media 2021-09-08
Subjects:PPRV, Adenovirus, Immune response, Vaccines, Viral vector,
Online Access:http://hdl.handle.net/10261/282769
http://dx.doi.org/10.13039/501100004837
http://dx.doi.org/10.13039/100012818
http://dx.doi.org/10.13039/501100000780
https://api.elsevier.com/content/abstract/scopus_id/85115413118
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spelling dig-inia-es-10261-2827692024-10-28T21:36:43Z A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates Rojas, José Manuel Sevilla, Noemí Martín, Verónica Ministerio de Ciencia e Innovación (España) Comunidad de Madrid European Commission Rojas, José Manuel [0000-0002-4055-3967] Sevilla, Noemí [0000-0003-0118-0376] Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] PPRV Adenovirus Immune response Vaccines Viral vector 14 Pág. Centro de Investigación en Sanidad Animal (CISA) Peste des petits ruminants virus (PPRV) is a virus that mainly infects goats and sheep causing significant economic loss in Africa and Asia, but also posing a serious threat to Europe, as recent outbreaks in Georgia (2016) and Bulgaria (2018) have been reported. In order to carry out the eradication of PPRV, an objective set for 2030 by the Office International des Epizooties (OIE) and the Food and Agriculture Organization of the United Nations (FAO), close collaboration between governments, pharmaceutical companies, farmers and researchers, among others, is needed. Today, more than ever, as seen in the response to the SARS-CoV2 pandemic that we are currently experiencing, these goals are feasible. We summarize in this review the current vaccination approaches against PPRV in the field, discussing their advantages and shortfalls, as well as the development and generation of new vaccination strategies, focusing on the potential use of adenovirus as vaccine platform against PPRV and more broadly against other ruminant pathogens. This work was supported by grant RTI2018-094616-B-100 from the Spanish Ministerio de Ciencia e Innovación; grant S2018/BAA-4370-PLATESA2 from the Comunidad de Madrid (Fondo Europeo de Desarrollo Regional, FEDER) and VetBionet INFRAIA-731014 from the European Union H2020. Peer reviewed 2022-11-11T12:44:04Z 2022-11-11T12:44:04Z 2021-09-08 artículo http://purl.org/coar/resource_type/c_6501 Frontiers in Veterinary Science 8: 729879 (2021) 2297-1769 http://hdl.handle.net/10261/282769 10.3389/fvets.2021.729879 http://dx.doi.org/10.13039/501100004837 http://dx.doi.org/10.13039/100012818 http://dx.doi.org/10.13039/501100000780 34568477 2-s2.0-85115413118 https://api.elsevier.com/content/abstract/scopus_id/85115413118 en #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-094616-B-I00/ES/ESTUDIO DE BIOLOGIA DE SISTEMAS PARA DESCIFRAR LOS MECANISMOS DE PROTECCION INMUNE FRENTE AL VIRUS DE LA LENGUA AZUL (BTV) Y EL VIRUS DE LOS PEQUEÑOS RUMIANTES (PPRV)/ S2018/BAA-4370/PLATESA2 info:eu-repo/grantAgreement/EC/H2020/731014 Frontiers in veterinary science Publisher's version https://doi.org/10.3389/fvets.2021.729879 Sí open Frontiers Media
institution INIA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-inia-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del INIA España
language English
topic PPRV
Adenovirus
Immune response
Vaccines
Viral vector
PPRV
Adenovirus
Immune response
Vaccines
Viral vector
spellingShingle PPRV
Adenovirus
Immune response
Vaccines
Viral vector
PPRV
Adenovirus
Immune response
Vaccines
Viral vector
Rojas, José Manuel
Sevilla, Noemí
Martín, Verónica
A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates
description 14 Pág. Centro de Investigación en Sanidad Animal (CISA)
author2 Ministerio de Ciencia e Innovación (España)
author_facet Ministerio de Ciencia e Innovación (España)
Rojas, José Manuel
Sevilla, Noemí
Martín, Verónica
format artículo
topic_facet PPRV
Adenovirus
Immune response
Vaccines
Viral vector
author Rojas, José Manuel
Sevilla, Noemí
Martín, Verónica
author_sort Rojas, José Manuel
title A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates
title_short A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates
title_full A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates
title_fullStr A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates
title_full_unstemmed A New Look at Vaccine Strategies Against PPRV Focused on Adenoviral Candidates
title_sort new look at vaccine strategies against pprv focused on adenoviral candidates
publisher Frontiers Media
publishDate 2021-09-08
url http://hdl.handle.net/10261/282769
http://dx.doi.org/10.13039/501100004837
http://dx.doi.org/10.13039/100012818
http://dx.doi.org/10.13039/501100000780
https://api.elsevier.com/content/abstract/scopus_id/85115413118
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AT rojasjosemanuel newlookatvaccinestrategiesagainstpprvfocusedonadenoviralcandidates
AT sevillanoemi newlookatvaccinestrategiesagainstpprvfocusedonadenoviralcandidates
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