Testing albendazole resistance in Fasciola hepatica
8 páginas.
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Humana Press
2020
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Subjects: | Albendazole, Diagnostic, Egg development test, Fasciola hepatica, Ovicidal activity, Resistance, |
Online Access: | http://hdl.handle.net/10261/237805 |
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dig-igm-es-10261-2378052021-04-14T01:13:27Z Testing albendazole resistance in Fasciola hepatica Alvarez, L.I. Martínez Valladares, María Canton, M.C. Lanusse, C.E. Ceballos, L. Albendazole Diagnostic Egg development test Fasciola hepatica Ovicidal activity Resistance 8 páginas. The egg development test is a useful in vitro tool to detect albendazole (ABZ) resistance in Fasciola hepatica. ABZ is the only flukicidal compound with ovicidal activity. The described test is based on the ABZ capacity to affect parasite egg development and hatching in susceptible parasites, while this effect is lost in ABZ-resistant liver fluke isolates. Among many advantages, it is noted that the diagnostic test can be performed on eggs isolated from fecal samples (sheep and cattle), avoiding the sacrifice of animals necessary in controlled efficacy trials. The egg development test described here is a simple, inexpensive, and accessible method, previously employed for diagnosis of ABZ resistance in F. hepatica. 2021-04-13T10:00:17Z 2021-04-13T10:00:17Z 2020 2021-04-13T10:00:18Z capítulo de libro http://purl.org/coar/resource_type/c_3248 doi: 10.1007/978-1-0716-0475-5_16 isbn: 978-1-0716-0474-8 Fasciola hepatica: 213- 220 (2020) http://hdl.handle.net/10261/237805 10.1007/978-1-0716-0475-5_16 Methods in Molecular Biology 2137 http://dx.doi.org/10.1007/978-1-0716-0475-5_16 Sí none Humana Press |
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Albendazole Diagnostic Egg development test Fasciola hepatica Ovicidal activity Resistance Albendazole Diagnostic Egg development test Fasciola hepatica Ovicidal activity Resistance |
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Albendazole Diagnostic Egg development test Fasciola hepatica Ovicidal activity Resistance Albendazole Diagnostic Egg development test Fasciola hepatica Ovicidal activity Resistance Alvarez, L.I. Martínez Valladares, María Canton, M.C. Lanusse, C.E. Ceballos, L. Testing albendazole resistance in Fasciola hepatica |
description |
8 páginas. |
format |
capítulo de libro |
topic_facet |
Albendazole Diagnostic Egg development test Fasciola hepatica Ovicidal activity Resistance |
author |
Alvarez, L.I. Martínez Valladares, María Canton, M.C. Lanusse, C.E. Ceballos, L. |
author_facet |
Alvarez, L.I. Martínez Valladares, María Canton, M.C. Lanusse, C.E. Ceballos, L. |
author_sort |
Alvarez, L.I. |
title |
Testing albendazole resistance in Fasciola hepatica |
title_short |
Testing albendazole resistance in Fasciola hepatica |
title_full |
Testing albendazole resistance in Fasciola hepatica |
title_fullStr |
Testing albendazole resistance in Fasciola hepatica |
title_full_unstemmed |
Testing albendazole resistance in Fasciola hepatica |
title_sort |
testing albendazole resistance in fasciola hepatica |
publisher |
Humana Press |
publishDate |
2020 |
url |
http://hdl.handle.net/10261/237805 |
work_keys_str_mv |
AT alvarezli testingalbendazoleresistanceinfasciolahepatica AT martinezvalladaresmaria testingalbendazoleresistanceinfasciolahepatica AT cantonmc testingalbendazoleresistanceinfasciolahepatica AT lanussece testingalbendazoleresistanceinfasciolahepatica AT ceballosl testingalbendazoleresistanceinfasciolahepatica |
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1777664086383788032 |