Linguistic and maternal genetic diversity are not correlated in Native Mexicans
11 páginas, 2 figuras, 3 tablas.-- Artículo Open Access: This article is distributed under the terms of the Creative Commons Attribution Noncommercial License.-- et al.
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2009-10
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dig-ibe-es-10261-437212021-12-28T16:49:36Z Linguistic and maternal genetic diversity are not correlated in Native Mexicans Sandoval-Mendoza, Karla Calafell, Francesc Comas, David 11 páginas, 2 figuras, 3 tablas.-- Artículo Open Access: This article is distributed under the terms of the Creative Commons Attribution Noncommercial License.-- et al. Mesoamerica, defined as the broad linguistic and cultural area from middle southern Mexico to Costa Rica, might have played a pivotal role during the colonization of the American continent. The Mesoamerican isthmus has constituted an important geographic barrier that has severely restricted gene flow between North and South America in pre-historical times. Although the Native American component has been already described in admixed Mexican populations, few studies have been carried out in native Mexican populations. In this study, we present mitochondrial DNA (mtDNA) sequence data for the first hypervariable region (HVR-I) in 477 unrelated individuals belonging to 11 different native populations from Mexico. Almost all of the Native Mexican mtDNAs could be classified into the four pan-Amerindian haplogroups (A2, B2, C1, and D1); only two of them could be allocated to the rare Native American lineage D4h3. Their haplogroup phylogenies are clearly star-like, as expected from relatively young populations that have experienced diverse episodes of genetic drift (e.g., extensive isolation, genetic drift, and founder effects) and posterior population expansions. In agreement with this observation, Native Mexican populations show a high degree of heterogeneity in their patterns of haplogroup frequencies. Haplogroup X2a was absent in our samples, supporting previous observations where this clade was only detected in the American northernmost areas. The search for identical sequences in the American continent shows that, although Native Mexican populations seem to show a closer relationship to North American populations, they cannot be related to a single geographical region within the continent. Finally, we did not find significant population structure in the maternal lineages when considering the four main and distinct linguistic groups represented in our Mexican samples (Oto-Manguean, Uto-Aztecan, Tarascan, and Mayan), suggesting that genetic divergence predates linguistic diversification in Mexico. This research was supported by the Agencia Española de Cooperación Internacional (AECI, Programa de Cooperacio´n Interuniversitaria e Investigación Científica entre España e Iberoamérica) (A/7694/07) and Direcció General de Recerca, Generalitat de Catalunya (2005SGR/00608). Karla Sandoval received a fellowship from the Consejo Nacional de Ciencia y Tecnología (CONACyT), México. Peer reviewed 2011-12-26T12:19:25Z 2011-12-26T12:19:25Z 2009-10 artículo http://purl.org/coar/resource_type/c_6501 Human Genetics 126(4): 521-531 (2009) 0340-6717 http://hdl.handle.net/10261/43721 10.1007/s00439-009-0693-y 1432-1203 19495796 en http://dx.doi.org/10.1007/s00439-009-0693-y open Springer |
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11 páginas, 2 figuras, 3 tablas.-- Artículo Open Access: This article is distributed under the terms of the
Creative Commons Attribution Noncommercial License.-- et al. |
| format |
artículo |
| author |
Sandoval-Mendoza, Karla Calafell, Francesc Comas, David |
| spellingShingle |
Sandoval-Mendoza, Karla Calafell, Francesc Comas, David Linguistic and maternal genetic diversity are not correlated in Native Mexicans |
| author_facet |
Sandoval-Mendoza, Karla Calafell, Francesc Comas, David |
| author_sort |
Sandoval-Mendoza, Karla |
| title |
Linguistic and maternal genetic diversity are not correlated in Native Mexicans |
| title_short |
Linguistic and maternal genetic diversity are not correlated in Native Mexicans |
| title_full |
Linguistic and maternal genetic diversity are not correlated in Native Mexicans |
| title_fullStr |
Linguistic and maternal genetic diversity are not correlated in Native Mexicans |
| title_full_unstemmed |
Linguistic and maternal genetic diversity are not correlated in Native Mexicans |
| title_sort |
linguistic and maternal genetic diversity are not correlated in native mexicans |
| publisher |
Springer |
| publishDate |
2009-10 |
| url |
http://hdl.handle.net/10261/43721 |
| work_keys_str_mv |
AT sandovalmendozakarla linguisticandmaternalgeneticdiversityarenotcorrelatedinnativemexicans AT calafellfrancesc linguisticandmaternalgeneticdiversityarenotcorrelatedinnativemexicans AT comasdavid linguisticandmaternalgeneticdiversityarenotcorrelatedinnativemexicans |
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1777668539960786944 |