Antimicrobial Nanofiber Based Filters for High Filtration Efficiency Respirators

Electrospinning has been used to develop and upscale polyacrylonitrile (PAN) nanofibers as effective aerosol filtration materials for their potential use in respirators. The fibers were deposited onto non-woven spunbond polypropylene (SPP) and the basis weight (grammage, g/m2) was varied to assess the resulting effect on filtration efficiency and breathing resistance of the materials. The results indicated that a basis weight in excess of 0.4 g/m2 of PAN electrospun fibers yielded a filtration efficiency over 97%, with breathing resistance values that increased proportionally with the amount of basis weight added. With the aim of retaining filter efficiency whilst lowering breathing resistance, the basis weight of 0.4 g/m2 and 0.8 g/m2 of PAN electrospun fibers were strategically split up and stacked with SPP in different configurations. The results suggested that a symmetric structure based on SPP/PAN/PAN/SPP was the optimal structure, as it reduces SPP consumption while maintaining an FFP2-type of filtration efficiency, while reducing breathing resistance, specially at high air flow rates, such as those mimicking FFP2 exhalation conditions. The incorporation of zinc oxide (ZnO) nanoparticles within the electrospun nanofibers in the form of nanocomposites, retained the high filtration characteristics of the unfilled filter, while exhibiting a strong bactericidal capacity, even after short contact times. This study demonstrates the potential of using the symmetric splitting of the PAN nanofibers layer as a somewhat more efficient configuration in the design of filters for respirators.

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Bibliographic Details
Main Authors: Pardo Figuérez, María, Chiva Flor, Alberto, Figueroa-Lopez, Kelly J., Prieto, Cristina, Lagarón Cabello, José María
Other Authors: Generalitat Valenciana
Format: artículo biblioteca
Language:English
Published: Multidisciplinary Digital Publishing Institute 2021-04-01
Subjects:Nanofibers, Respirators, Antimicrobials, SARS-CoV-2, Electrospinning,
Online Access:http://hdl.handle.net/10261/243816
http://dx.doi.org/10.13039/501100003339
http://dx.doi.org/10.13039/501100003359
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spelling dig-iata-es-10261-2438162023-02-06T13:12:15Z Antimicrobial Nanofiber Based Filters for High Filtration Efficiency Respirators Pardo Figuérez, María Chiva Flor, Alberto Figueroa-Lopez, Kelly J. Prieto, Cristina Lagarón Cabello, José María Generalitat Valenciana Consejo Superior de Investigaciones Científicas (España) Nanofibers Respirators Antimicrobials SARS-CoV-2 Electrospinning Electrospinning has been used to develop and upscale polyacrylonitrile (PAN) nanofibers as effective aerosol filtration materials for their potential use in respirators. The fibers were deposited onto non-woven spunbond polypropylene (SPP) and the basis weight (grammage, g/m2) was varied to assess the resulting effect on filtration efficiency and breathing resistance of the materials. The results indicated that a basis weight in excess of 0.4 g/m2 of PAN electrospun fibers yielded a filtration efficiency over 97%, with breathing resistance values that increased proportionally with the amount of basis weight added. With the aim of retaining filter efficiency whilst lowering breathing resistance, the basis weight of 0.4 g/m2 and 0.8 g/m2 of PAN electrospun fibers were strategically split up and stacked with SPP in different configurations. The results suggested that a symmetric structure based on SPP/PAN/PAN/SPP was the optimal structure, as it reduces SPP consumption while maintaining an FFP2-type of filtration efficiency, while reducing breathing resistance, specially at high air flow rates, such as those mimicking FFP2 exhalation conditions. The incorporation of zinc oxide (ZnO) nanoparticles within the electrospun nanofibers in the form of nanocomposites, retained the high filtration characteristics of the unfilled filter, while exhibiting a strong bactericidal capacity, even after short contact times. This study demonstrates the potential of using the symmetric splitting of the PAN nanofibers layer as a somewhat more efficient configuration in the design of filters for respirators. This work has been funded by the project “Urgent aid for the financing of scientific-innovative solutions directly related for the fight against COVID-19”, project AVI-COVID19/Nº28 funded by the Generalitat Valenciana and project Intramural CSIC 202070E104 funded by the COVID-19 Research platform “Salud Global” from the Spanish Council for Scientific Research (CSIC). Peer reviewed 2021-06-17T06:05:39Z 2021-06-17T06:05:39Z 2021-04-01 artículo http://purl.org/coar/resource_type/c_6501 Nanomaterials 11(4): 900 (2021) http://hdl.handle.net/10261/243816 10.3390/nano11040900 2079-4991 http://dx.doi.org/10.13039/501100003339 http://dx.doi.org/10.13039/501100003359 33915897 en Publisher's version https://doi.org/10.3390/nano11040900 Sí open Multidisciplinary Digital Publishing Institute
institution IATA ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-iata-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del IATA España
language English
topic Nanofibers
Respirators
Antimicrobials
SARS-CoV-2
Electrospinning
Nanofibers
Respirators
Antimicrobials
SARS-CoV-2
Electrospinning
spellingShingle Nanofibers
Respirators
Antimicrobials
SARS-CoV-2
Electrospinning
Nanofibers
Respirators
Antimicrobials
SARS-CoV-2
Electrospinning
Pardo Figuérez, María
Chiva Flor, Alberto
Figueroa-Lopez, Kelly J.
Prieto, Cristina
Lagarón Cabello, José María
Antimicrobial Nanofiber Based Filters for High Filtration Efficiency Respirators
description Electrospinning has been used to develop and upscale polyacrylonitrile (PAN) nanofibers as effective aerosol filtration materials for their potential use in respirators. The fibers were deposited onto non-woven spunbond polypropylene (SPP) and the basis weight (grammage, g/m2) was varied to assess the resulting effect on filtration efficiency and breathing resistance of the materials. The results indicated that a basis weight in excess of 0.4 g/m2 of PAN electrospun fibers yielded a filtration efficiency over 97%, with breathing resistance values that increased proportionally with the amount of basis weight added. With the aim of retaining filter efficiency whilst lowering breathing resistance, the basis weight of 0.4 g/m2 and 0.8 g/m2 of PAN electrospun fibers were strategically split up and stacked with SPP in different configurations. The results suggested that a symmetric structure based on SPP/PAN/PAN/SPP was the optimal structure, as it reduces SPP consumption while maintaining an FFP2-type of filtration efficiency, while reducing breathing resistance, specially at high air flow rates, such as those mimicking FFP2 exhalation conditions. The incorporation of zinc oxide (ZnO) nanoparticles within the electrospun nanofibers in the form of nanocomposites, retained the high filtration characteristics of the unfilled filter, while exhibiting a strong bactericidal capacity, even after short contact times. This study demonstrates the potential of using the symmetric splitting of the PAN nanofibers layer as a somewhat more efficient configuration in the design of filters for respirators.
author2 Generalitat Valenciana
author_facet Generalitat Valenciana
Pardo Figuérez, María
Chiva Flor, Alberto
Figueroa-Lopez, Kelly J.
Prieto, Cristina
Lagarón Cabello, José María
format artículo
topic_facet Nanofibers
Respirators
Antimicrobials
SARS-CoV-2
Electrospinning
author Pardo Figuérez, María
Chiva Flor, Alberto
Figueroa-Lopez, Kelly J.
Prieto, Cristina
Lagarón Cabello, José María
author_sort Pardo Figuérez, María
title Antimicrobial Nanofiber Based Filters for High Filtration Efficiency Respirators
title_short Antimicrobial Nanofiber Based Filters for High Filtration Efficiency Respirators
title_full Antimicrobial Nanofiber Based Filters for High Filtration Efficiency Respirators
title_fullStr Antimicrobial Nanofiber Based Filters for High Filtration Efficiency Respirators
title_full_unstemmed Antimicrobial Nanofiber Based Filters for High Filtration Efficiency Respirators
title_sort antimicrobial nanofiber based filters for high filtration efficiency respirators
publisher Multidisciplinary Digital Publishing Institute
publishDate 2021-04-01
url http://hdl.handle.net/10261/243816
http://dx.doi.org/10.13039/501100003339
http://dx.doi.org/10.13039/501100003359
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