Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar
In Madagascar, little information about drug residues in animal products is available. However, recently, official veterinary services were informed about the misuse of human injectable contraceptives in pig farms as an alternative for chirurgical castration of adult sows before culling. We investigated pigs (n = 80) slaughtered in 7 Malagasy abattoirs and raised in 8 of the 22 Malagasy regions (1) to confirm the contamination of carcasses by anabolic hormones by using LC-MS/MS, (2) to identify the substances of concern and (3) to explore the consumers' exposure to hormone residues. Medroxyprogesterone acetate was the only synthetic hormone detected in kidney fat. Samples positive with medroxyprogesterone acetate were observed in 66.7% of the districts investigated and in 87.5% of the surveyed regions, confirming its large misuse in livestock. Public awareness campaigns and control improvement among the animal production sector and among the Malagasy public health sector are therefore urgent.
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Subjects: | Q03 - Contamination et toxicologie alimentaires, L53 - Physiologie animale - Reproduction, L70 - Sciences et hygiène vétérinaires - Considérations générales, contamination chimique, viande porcine, produit carné, hormone, Contraceptif, résidu de médicament, http://aims.fao.org/aos/agrovoc/c_28319, http://aims.fao.org/aos/agrovoc/c_6120, http://aims.fao.org/aos/agrovoc/c_4680, http://aims.fao.org/aos/agrovoc/c_3663, http://aims.fao.org/aos/agrovoc/c_1838, http://aims.fao.org/aos/agrovoc/c_10470, http://aims.fao.org/aos/agrovoc/c_4510, |
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dig-cirad-fr-5716412024-02-06T15:34:18Z http://agritrop.cirad.fr/571641/ http://agritrop.cirad.fr/571641/ Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar. Porphyre Vincent, Rakotoharinome Vincent Michel, Randriamparany Tantely, Pognon Damien, Prévost Stéphanie, Le Bizec Bruno. 2013. Food Additives and Contaminants. Part A. Chemistry, Analysis, Control, Exposure and Risk Assessment, 30 (12) : 2108-2113.https://doi.org/10.1080/19440049.2013.848293 <https://doi.org/10.1080/19440049.2013.848293> Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar Porphyre, Vincent Rakotoharinome, Vincent Michel Randriamparany, Tantely Pognon, Damien Prévost, Stéphanie Le Bizec, Bruno eng 2013 Food Additives and Contaminants. Part A. Chemistry, Analysis, Control, Exposure and Risk Assessment Q03 - Contamination et toxicologie alimentaires L53 - Physiologie animale - Reproduction L70 - Sciences et hygiène vétérinaires - Considérations générales contamination chimique viande porcine produit carné hormone Contraceptif résidu de médicament http://aims.fao.org/aos/agrovoc/c_28319 http://aims.fao.org/aos/agrovoc/c_6120 http://aims.fao.org/aos/agrovoc/c_4680 http://aims.fao.org/aos/agrovoc/c_3663 http://aims.fao.org/aos/agrovoc/c_1838 http://aims.fao.org/aos/agrovoc/c_10470 Madagascar http://aims.fao.org/aos/agrovoc/c_4510 In Madagascar, little information about drug residues in animal products is available. However, recently, official veterinary services were informed about the misuse of human injectable contraceptives in pig farms as an alternative for chirurgical castration of adult sows before culling. We investigated pigs (n = 80) slaughtered in 7 Malagasy abattoirs and raised in 8 of the 22 Malagasy regions (1) to confirm the contamination of carcasses by anabolic hormones by using LC-MS/MS, (2) to identify the substances of concern and (3) to explore the consumers' exposure to hormone residues. Medroxyprogesterone acetate was the only synthetic hormone detected in kidney fat. Samples positive with medroxyprogesterone acetate were observed in 66.7% of the districts investigated and in 87.5% of the surveyed regions, confirming its large misuse in livestock. Public awareness campaigns and control improvement among the animal production sector and among the Malagasy public health sector are therefore urgent. article info:eu-repo/semantics/article Journal Article info:eu-repo/semantics/publishedVersion http://agritrop.cirad.fr/571641/1/document_571641.pdf application/pdf Cirad license info:eu-repo/semantics/restrictedAccess https://agritrop.cirad.fr/mention_legale.html https://doi.org/10.1080/19440049.2013.848293 10.1080/19440049.2013.848293 info:eu-repo/semantics/altIdentifier/doi/10.1080/19440049.2013.848293 info:eu-repo/semantics/altIdentifier/purl/https://doi.org/10.1080/19440049.2013.848293 |
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Q03 - Contamination et toxicologie alimentaires L53 - Physiologie animale - Reproduction L70 - Sciences et hygiène vétérinaires - Considérations générales contamination chimique viande porcine produit carné hormone Contraceptif résidu de médicament http://aims.fao.org/aos/agrovoc/c_28319 http://aims.fao.org/aos/agrovoc/c_6120 http://aims.fao.org/aos/agrovoc/c_4680 http://aims.fao.org/aos/agrovoc/c_3663 http://aims.fao.org/aos/agrovoc/c_1838 http://aims.fao.org/aos/agrovoc/c_10470 http://aims.fao.org/aos/agrovoc/c_4510 Q03 - Contamination et toxicologie alimentaires L53 - Physiologie animale - Reproduction L70 - Sciences et hygiène vétérinaires - Considérations générales contamination chimique viande porcine produit carné hormone Contraceptif résidu de médicament http://aims.fao.org/aos/agrovoc/c_28319 http://aims.fao.org/aos/agrovoc/c_6120 http://aims.fao.org/aos/agrovoc/c_4680 http://aims.fao.org/aos/agrovoc/c_3663 http://aims.fao.org/aos/agrovoc/c_1838 http://aims.fao.org/aos/agrovoc/c_10470 http://aims.fao.org/aos/agrovoc/c_4510 |
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Q03 - Contamination et toxicologie alimentaires L53 - Physiologie animale - Reproduction L70 - Sciences et hygiène vétérinaires - Considérations générales contamination chimique viande porcine produit carné hormone Contraceptif résidu de médicament http://aims.fao.org/aos/agrovoc/c_28319 http://aims.fao.org/aos/agrovoc/c_6120 http://aims.fao.org/aos/agrovoc/c_4680 http://aims.fao.org/aos/agrovoc/c_3663 http://aims.fao.org/aos/agrovoc/c_1838 http://aims.fao.org/aos/agrovoc/c_10470 http://aims.fao.org/aos/agrovoc/c_4510 Q03 - Contamination et toxicologie alimentaires L53 - Physiologie animale - Reproduction L70 - Sciences et hygiène vétérinaires - Considérations générales contamination chimique viande porcine produit carné hormone Contraceptif résidu de médicament http://aims.fao.org/aos/agrovoc/c_28319 http://aims.fao.org/aos/agrovoc/c_6120 http://aims.fao.org/aos/agrovoc/c_4680 http://aims.fao.org/aos/agrovoc/c_3663 http://aims.fao.org/aos/agrovoc/c_1838 http://aims.fao.org/aos/agrovoc/c_10470 http://aims.fao.org/aos/agrovoc/c_4510 Porphyre, Vincent Rakotoharinome, Vincent Michel Randriamparany, Tantely Pognon, Damien Prévost, Stéphanie Le Bizec, Bruno Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar |
description |
In Madagascar, little information about drug residues in animal products is available. However, recently, official veterinary services were informed about the misuse of human injectable contraceptives in pig farms as an alternative for chirurgical castration of adult sows before culling. We investigated pigs (n = 80) slaughtered in 7 Malagasy abattoirs and raised in 8 of the 22 Malagasy regions (1) to confirm the contamination of carcasses by anabolic hormones by using LC-MS/MS, (2) to identify the substances of concern and (3) to explore the consumers' exposure to hormone residues. Medroxyprogesterone acetate was the only synthetic hormone detected in kidney fat. Samples positive with medroxyprogesterone acetate were observed in 66.7% of the districts investigated and in 87.5% of the surveyed regions, confirming its large misuse in livestock. Public awareness campaigns and control improvement among the animal production sector and among the Malagasy public health sector are therefore urgent. |
format |
article |
topic_facet |
Q03 - Contamination et toxicologie alimentaires L53 - Physiologie animale - Reproduction L70 - Sciences et hygiène vétérinaires - Considérations générales contamination chimique viande porcine produit carné hormone Contraceptif résidu de médicament http://aims.fao.org/aos/agrovoc/c_28319 http://aims.fao.org/aos/agrovoc/c_6120 http://aims.fao.org/aos/agrovoc/c_4680 http://aims.fao.org/aos/agrovoc/c_3663 http://aims.fao.org/aos/agrovoc/c_1838 http://aims.fao.org/aos/agrovoc/c_10470 http://aims.fao.org/aos/agrovoc/c_4510 |
author |
Porphyre, Vincent Rakotoharinome, Vincent Michel Randriamparany, Tantely Pognon, Damien Prévost, Stéphanie Le Bizec, Bruno |
author_facet |
Porphyre, Vincent Rakotoharinome, Vincent Michel Randriamparany, Tantely Pognon, Damien Prévost, Stéphanie Le Bizec, Bruno |
author_sort |
Porphyre, Vincent |
title |
Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar |
title_short |
Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar |
title_full |
Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar |
title_fullStr |
Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar |
title_full_unstemmed |
Residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, Madagascar |
title_sort |
residues of medroxyprogesterone acetate detected in sows at a slaughterhouse, madagascar |
url |
http://agritrop.cirad.fr/571641/ http://agritrop.cirad.fr/571641/1/document_571641.pdf |
work_keys_str_mv |
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_version_ |
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