Potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome

Potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome

This article belongs to the Special Issue New Insights on Bioactive Compounds for the Prevention and Management of Metabolic Syndrome.

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Main Authors: Garcés-Rimón, Marta, Morales, Diego, Miguel, Marta
Other Authors: Ministerio de Ciencia, Innovación y Universidades (España)
Format: artículo biblioteca
Language:English
Published: Multidisciplinary Digital Publishing Institute 2022
Subjects:Legumes, Metabolic syndrome, Bioactive peptides, Antihypertensive, Antioxidant, Hypocholesterolemic,
Online Access:http://hdl.handle.net/10261/303031
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spelling dig-cial-es-10261-3030312023-03-14T07:38:39Z Potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome Garcés-Rimón, Marta Morales, Diego Miguel, Marta Ministerio de Ciencia, Innovación y Universidades (España) Agencia Estatal de Investigación (España) Universidad Francisco de Vitoria Legumes Metabolic syndrome Bioactive peptides Antihypertensive Antioxidant Hypocholesterolemic This article belongs to the Special Issue New Insights on Bioactive Compounds for the Prevention and Management of Metabolic Syndrome. Legumes have been widely consumed and used to isolate bioactive compounds, mainly proteins. The aim of this study was to review the beneficial actions of different legumes proteins and peptides updating the main findings that correlate legumes consumption and the effects on non-transmissible chronic diseases, specifically metabolic syndrome. An exhaustive revision of five relevant bioactivities (antioxidant, anti-inflammatory, antihypertensive, hypocholesterolemic -all of them linked to metabolic syndrome- and antitumoral) of proteins and peptides from legumes focused on isolation and purification, enzymatic hydrolysis and in vitro gastrointestinal digestion was carried out. The promising potential of bioactive hydrolysates and peptides from pulses has been demonstrated by in vitro tests. However, only a few studies validated these biological activities using animal models. No clinical trials have been carried out yet; so further research is required to elucidate their effective health implications. This research was funded by the Spanish Ministry of Education, Science and Universities (MICINN; AGL2017-89213) and Francisco de Vitoria University (UFV 2019-09). D.M. thanks to Spanish Ministry of Science and Innovation (MICINN) for the Juan de la Cierva Formación Fellowship (FJC2020-044585-I). Peer reviewed 2023-03-14T07:38:39Z 2023-03-14T07:38:39Z 2022 artículo Nutrients 14(24): 5271 (2022) http://hdl.handle.net/10261/303031 10.3390/nu14245271 2072-6643 en #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2017-89213-R/ES/HIDROLISIS DE PROTEINAS VEGETALES DE ALTO VALOR BIOLOGICO: OBTENCION DE PEPTIDOS ANTIOXIDANTES Y NUEVAS TEXTURAS CULINARIAS PARA LA ELABORACION DE PRODUCTOS SIN GLUTEN/ info:eu-repo/grantAgreement/AEI//FJC2020-044585-I Nutrients Publisher's version https://doi.org/10.3390/nu14245271 Sí open application/pdf Multidisciplinary Digital Publishing Institute
institution CIAL ES
collection DSpace
country España
countrycode ES
component Bibliográfico
access En linea
databasecode dig-cial-es
tag biblioteca
region Europa del Sur
libraryname Biblioteca del CIAL España
language English
topic Legumes
Metabolic syndrome
Bioactive peptides
Antihypertensive
Antioxidant
Hypocholesterolemic
Legumes
Metabolic syndrome
Bioactive peptides
Antihypertensive
Antioxidant
Hypocholesterolemic
spellingShingle Legumes
Metabolic syndrome
Bioactive peptides
Antihypertensive
Antioxidant
Hypocholesterolemic
Legumes
Metabolic syndrome
Bioactive peptides
Antihypertensive
Antioxidant
Hypocholesterolemic
Garcés-Rimón, Marta
Morales, Diego
Miguel, Marta
Potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome
description This article belongs to the Special Issue New Insights on Bioactive Compounds for the Prevention and Management of Metabolic Syndrome.
author2 Ministerio de Ciencia, Innovación y Universidades (España)
author_facet Ministerio de Ciencia, Innovación y Universidades (España)
Garcés-Rimón, Marta
Morales, Diego
Miguel, Marta
format artículo
topic_facet Legumes
Metabolic syndrome
Bioactive peptides
Antihypertensive
Antioxidant
Hypocholesterolemic
author Garcés-Rimón, Marta
Morales, Diego
Miguel, Marta
author_sort Garcés-Rimón, Marta
title Potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome
title_short Potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome
title_full Potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome
title_fullStr Potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome
title_full_unstemmed Potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome
title_sort potential role of bioactive proteins and peptides derived from legumes towards metabolic syndrome
publisher Multidisciplinary Digital Publishing Institute
publishDate 2022
url http://hdl.handle.net/10261/303031
work_keys_str_mv AT garcesrimonmarta potentialroleofbioactiveproteinsandpeptidesderivedfromlegumestowardsmetabolicsyndrome
AT moralesdiego potentialroleofbioactiveproteinsandpeptidesderivedfromlegumestowardsmetabolicsyndrome
AT miguelmarta potentialroleofbioactiveproteinsandpeptidesderivedfromlegumestowardsmetabolicsyndrome
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