State of antioxidant protection and detoxification systems in the tissues of gobies and carp fish after exposure to fungicides of a new generation

The effect of two novel carboxamide fungicides, Ethaboxam and Boscalid, on round goby fry and carp fingerlings has been studied. Boscalid is characterized to be highly toxic when applied to round goby fries, Ethaboxam is of medium toxicity to commercial fish species. In the early stages of intoxication (1st - 4th day) the threshold concentrations of the fungicides acted as stressors and resulted in the stimulation of protective systems of the antioxidant protection and detoxification in the liver and gills of carp and round goby tissues, which hindered the development of fungicide intoxication. Intensification of lipid peroxidation processes led to the inhibition of superoxide dismutase activity alongside with the increased activity of catalase, esterases, glutathione-S-transferase, while glutathione content in fish tissues decreased gradually.

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Bibliographic Details
Main Authors: Levina, I.L., Kuznetsova, L.Ya., Shcherbakova, N.I., Zinchuk, O.A.
Other Authors: Belousov, V.N.
Format: Journal Contribution biblioteca
Language:Russian
Published: 2017
Subjects:Fungicides, Catalase, Round goby, Carp, Fish fry, Antioxidants, Liver, Gills, Inhibition, Intoxication, Фунгициды, Бычок-кругляк, Жабры, Печень, Этабоксам, Боскалид, Интоксикация,
Online Access:http://hdl.handle.net/1834/17294
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Summary:The effect of two novel carboxamide fungicides, Ethaboxam and Boscalid, on round goby fry and carp fingerlings has been studied. Boscalid is characterized to be highly toxic when applied to round goby fries, Ethaboxam is of medium toxicity to commercial fish species. In the early stages of intoxication (1st - 4th day) the threshold concentrations of the fungicides acted as stressors and resulted in the stimulation of protective systems of the antioxidant protection and detoxification in the liver and gills of carp and round goby tissues, which hindered the development of fungicide intoxication. Intensification of lipid peroxidation processes led to the inhibition of superoxide dismutase activity alongside with the increased activity of catalase, esterases, glutathione-S-transferase, while glutathione content in fish tissues decreased gradually.