Humoral and cell-mediated immune responses in non-pregnant heifers following infection and vaccination with Brucella abortus
Humoral and cell-mediated-immune responses to Brucella abortus were observed in non-pregnant heifers following infection alone; infection followed by vaccination; vaccination followed by infection; and vaccination alone. The humoral responses, as measured by the Rose Bengal test (RBT), complement fixation test (CFT), indirect haemolysis test (IHLT) and the enzyme-linked immunosorbent assay (ELISA) tended to be immediate and transient following infection alone, infection following vaccination and vaccination alone. However, when vaccination was superimposed on infection, reactions were maintained for at least 2 years. The cell-mediated-immune (CMI) responses were assessed by the lymphocyte stimulation test. The responses occurred after the humoral responses had peaked and were present for periods of 6-22 weeks. However, the level of stimulation was greater following infection than following vaccination, and the response when vaccination was superimposed on infection was present for less than 6 months
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1988
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Subjects: | BACTERIOSIS, BRUCELOSIS, BRUCELLA ABORTUS, INMUNIZACION, RESPUESTA INMUNOLOGICA, NOVILLA, |
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KOHA-OAI-BVE:413122020-02-03T21:04:22ZHumoral and cell-mediated immune responses in non-pregnant heifers following infection and vaccination with Brucella abortus 131529 Wilkinson, R. 54145 Cargill, C. 85719 Lee, K. 1988Humoral and cell-mediated-immune responses to Brucella abortus were observed in non-pregnant heifers following infection alone; infection followed by vaccination; vaccination followed by infection; and vaccination alone. The humoral responses, as measured by the Rose Bengal test (RBT), complement fixation test (CFT), indirect haemolysis test (IHLT) and the enzyme-linked immunosorbent assay (ELISA) tended to be immediate and transient following infection alone, infection following vaccination and vaccination alone. However, when vaccination was superimposed on infection, reactions were maintained for at least 2 years. The cell-mediated-immune (CMI) responses were assessed by the lymphocyte stimulation test. The responses occurred after the humoral responses had peaked and were present for periods of 6-22 weeks. However, the level of stimulation was greater following infection than following vaccination, and the response when vaccination was superimposed on infection was present for less than 6 monthsHumoral and cell-mediated-immune responses to Brucella abortus were observed in non-pregnant heifers following infection alone; infection followed by vaccination; vaccination followed by infection; and vaccination alone. The humoral responses, as measured by the Rose Bengal test (RBT), complement fixation test (CFT), indirect haemolysis test (IHLT) and the enzyme-linked immunosorbent assay (ELISA) tended to be immediate and transient following infection alone, infection following vaccination and vaccination alone. However, when vaccination was superimposed on infection, reactions were maintained for at least 2 years. The cell-mediated-immune (CMI) responses were assessed by the lymphocyte stimulation test. The responses occurred after the humoral responses had peaked and were present for periods of 6-22 weeks. However, the level of stimulation was greater following infection than following vaccination, and the response when vaccination was superimposed on infection was present for less than 6 monthsBACTERIOSISBRUCELOSISBRUCELLA ABORTUSINMUNIZACIONRESPUESTA INMUNOLOGICANOVILLAVeterinary Immunology and Immunopathology (Países Bajos) |
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BACTERIOSIS BRUCELOSIS BRUCELLA ABORTUS INMUNIZACION RESPUESTA INMUNOLOGICA NOVILLA BACTERIOSIS BRUCELOSIS BRUCELLA ABORTUS INMUNIZACION RESPUESTA INMUNOLOGICA NOVILLA |
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BACTERIOSIS BRUCELOSIS BRUCELLA ABORTUS INMUNIZACION RESPUESTA INMUNOLOGICA NOVILLA BACTERIOSIS BRUCELOSIS BRUCELLA ABORTUS INMUNIZACION RESPUESTA INMUNOLOGICA NOVILLA 131529 Wilkinson, R. 54145 Cargill, C. 85719 Lee, K. Humoral and cell-mediated immune responses in non-pregnant heifers following infection and vaccination with Brucella abortus |
description |
Humoral and cell-mediated-immune responses to Brucella abortus were observed in non-pregnant heifers following infection alone; infection followed by vaccination; vaccination followed by infection; and vaccination alone. The humoral responses, as measured by the Rose Bengal test (RBT), complement fixation test (CFT), indirect haemolysis test (IHLT) and the enzyme-linked immunosorbent assay (ELISA) tended to be immediate and transient following infection alone, infection following vaccination and vaccination alone. However, when vaccination was superimposed on infection, reactions were maintained for at least 2 years. The cell-mediated-immune (CMI) responses were assessed by the lymphocyte stimulation test. The responses occurred after the humoral responses had peaked and were present for periods of 6-22 weeks. However, the level of stimulation was greater following infection than following vaccination, and the response when vaccination was superimposed on infection was present for less than 6 months |
format |
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topic_facet |
BACTERIOSIS BRUCELOSIS BRUCELLA ABORTUS INMUNIZACION RESPUESTA INMUNOLOGICA NOVILLA |
author |
131529 Wilkinson, R. 54145 Cargill, C. 85719 Lee, K. |
author_facet |
131529 Wilkinson, R. 54145 Cargill, C. 85719 Lee, K. |
author_sort |
131529 Wilkinson, R. |
title |
Humoral and cell-mediated immune responses in non-pregnant heifers following infection and vaccination with Brucella abortus |
title_short |
Humoral and cell-mediated immune responses in non-pregnant heifers following infection and vaccination with Brucella abortus |
title_full |
Humoral and cell-mediated immune responses in non-pregnant heifers following infection and vaccination with Brucella abortus |
title_fullStr |
Humoral and cell-mediated immune responses in non-pregnant heifers following infection and vaccination with Brucella abortus |
title_full_unstemmed |
Humoral and cell-mediated immune responses in non-pregnant heifers following infection and vaccination with Brucella abortus |
title_sort |
humoral and cell-mediated immune responses in non-pregnant heifers following infection and vaccination with brucella abortus |
publishDate |
1988 |
work_keys_str_mv |
AT 131529wilkinsonr humoralandcellmediatedimmuneresponsesinnonpregnantheifersfollowinginfectionandvaccinationwithbrucellaabortus AT 54145cargillc humoralandcellmediatedimmuneresponsesinnonpregnantheifersfollowinginfectionandvaccinationwithbrucellaabortus AT 85719leek humoralandcellmediatedimmuneresponsesinnonpregnantheifersfollowinginfectionandvaccinationwithbrucellaabortus |
_version_ |
1756053427642695680 |