Mutagenic and genotoxic potential of waste water from the tannery Tasajero, Cucuta, North Santander, Colombia

Mutagenic and genotoxic potential of waste water from the tannery Tasajero, Cucuta, North Santander, Colombia

Tanning is an industrial process that requires large volumes of water for the transformation of a putrescible material into a non-putrescible one, suitable to be used in manufactured products. The wastewater generated by this industry are generally discharged without previous treatment into water bodies, generating large amounts of biochemical demands of oxygen and chemical oxygen, high pH values, presence of toxic chemical substances that act as mutagens, increasing the risk of developing cancer in the exposed population. In the town of Cúcuta small tannery industries exist, which do not dispose the basic tools or knowledge regarding the proper waste treatment, therefore generating pollution of water, which afterwards can be used by the population. In the chemical process of this industry, chromium, lead, sulfides, zinc chromates and calcium, compounds considered among the most potent human carcinogens are used. The study included the analysis and determination of the mutagenicity and genotoxicity of wastewater from the tannery “Tasajero”. For genotoxicity determination the comet assay was used; for the mutagenicity analysis, the Ames test with Salmonella typhimurium strains TA98 and TA100 was employed. It was found that the wastewater from the evaluated tannery induces DNA damage in human lymphocytes. Similarly, the results indicate that this water increased the mutagenicity in the TA98 strain.

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Main Authors: Quijano Parra, Alfonso, Castillo T, Carol, Meléndez Gélvez, Iván
Format: Digital revista
Language:spa
Published: Universidad de Ciencias Aplicadas y Ambientales U.D.C.A 2015
Online Access:https://revistas.udca.edu.co/index.php/ruadc/article/view/449
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record_format ojs
institution UDCA CO
collection OJS
country Colombia
countrycode CO
component Revista
access En linea
databasecode rev-ruadc-co
tag revista
region America del Sur
libraryname Biblioteca de la UDCA de Colombia
language spa
format Digital
author Quijano Parra, Alfonso
Castillo T, Carol
Meléndez Gélvez, Iván
spellingShingle Quijano Parra, Alfonso
Castillo T, Carol
Meléndez Gélvez, Iván
Mutagenic and genotoxic potential of waste water from the tannery Tasajero, Cucuta, North Santander, Colombia
author_facet Quijano Parra, Alfonso
Castillo T, Carol
Meléndez Gélvez, Iván
author_sort Quijano Parra, Alfonso
title Mutagenic and genotoxic potential of waste water from the tannery Tasajero, Cucuta, North Santander, Colombia
title_short Mutagenic and genotoxic potential of waste water from the tannery Tasajero, Cucuta, North Santander, Colombia
title_full Mutagenic and genotoxic potential of waste water from the tannery Tasajero, Cucuta, North Santander, Colombia
title_fullStr Mutagenic and genotoxic potential of waste water from the tannery Tasajero, Cucuta, North Santander, Colombia
title_full_unstemmed Mutagenic and genotoxic potential of waste water from the tannery Tasajero, Cucuta, North Santander, Colombia
title_sort mutagenic and genotoxic potential of waste water from the tannery tasajero, cucuta, north santander, colombia
description Tanning is an industrial process that requires large volumes of water for the transformation of a putrescible material into a non-putrescible one, suitable to be used in manufactured products. The wastewater generated by this industry are generally discharged without previous treatment into water bodies, generating large amounts of biochemical demands of oxygen and chemical oxygen, high pH values, presence of toxic chemical substances that act as mutagens, increasing the risk of developing cancer in the exposed population. In the town of Cúcuta small tannery industries exist, which do not dispose the basic tools or knowledge regarding the proper waste treatment, therefore generating pollution of water, which afterwards can be used by the population. In the chemical process of this industry, chromium, lead, sulfides, zinc chromates and calcium, compounds considered among the most potent human carcinogens are used. The study included the analysis and determination of the mutagenicity and genotoxicity of wastewater from the tannery “Tasajero”. For genotoxicity determination the comet assay was used; for the mutagenicity analysis, the Ames test with Salmonella typhimurium strains TA98 and TA100 was employed. It was found that the wastewater from the evaluated tannery induces DNA damage in human lymphocytes. Similarly, the results indicate that this water increased the mutagenicity in the TA98 strain.
publisher Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
publishDate 2015
url https://revistas.udca.edu.co/index.php/ruadc/article/view/449
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spelling rev-ruadc-co-article-4492020-04-03T20:32:06Z Mutagenic and genotoxic potential of waste water from the tannery Tasajero, Cucuta, North Santander, Colombia Potencial mutagénico y genotóxico de aguas residuales de la curtiembre Tasajero en la ciudad de Cúcuta, Norte de Santander, Colombia Quijano Parra, Alfonso Castillo T, Carol Meléndez Gélvez, Iván Salmonella typhimurium TA98 TA100 metales pesados test de Ames ensayo cometa Salmonella typhimurium TA 98 TA100 heavy metals Ames test comet assay Tanning is an industrial process that requires large volumes of water for the transformation of a putrescible material into a non-putrescible one, suitable to be used in manufactured products. The wastewater generated by this industry are generally discharged without previous treatment into water bodies, generating large amounts of biochemical demands of oxygen and chemical oxygen, high pH values, presence of toxic chemical substances that act as mutagens, increasing the risk of developing cancer in the exposed population. In the town of Cúcuta small tannery industries exist, which do not dispose the basic tools or knowledge regarding the proper waste treatment, therefore generating pollution of water, which afterwards can be used by the population. In the chemical process of this industry, chromium, lead, sulfides, zinc chromates and calcium, compounds considered among the most potent human carcinogens are used. The study included the analysis and determination of the mutagenicity and genotoxicity of wastewater from the tannery “Tasajero”. For genotoxicity determination the comet assay was used; for the mutagenicity analysis, the Ames test with Salmonella typhimurium strains TA98 and TA100 was employed. It was found that the wastewater from the evaluated tannery induces DNA damage in human lymphocytes. Similarly, the results indicate that this water increased the mutagenicity in the TA98 strain. La curtición es un proceso industrial que requiere grandes volúmenes de agua para la transformación de un material putrescible en uno imputrescible, apto para su utilización, en productos manufacturados. Las aguas residuales generadas por dicha industria, generalmente, son vertidas a los cuerpos de agua sin tratamiento previo, generando así grandes cantidades de demandas bioquímicas de oxígeno y química de oxígeno, valores elevados de pH, presencia de sustancias químicas tóxicas, que actúan como mutágenos, aumentando así el riesgo de desarrollar cáncer en la población expuesta. En la ciudad de Cúcuta, se encuentran pequeñas industrias de curtiembres, que no poseen las herramientas básicas, ni conocimientos sobre el adecuado tratamiento de los residuos, generando contaminación en el recurso hídrico, que luego puede llegar a ser usado por la población. En los procesos químicos de esta industria, se usan el cromo, el plomo, los sulfuros, los cromatos de zinc y el calcio, compuestos considerados, entre los carcinógenos humanos, más potentes. El estudio contempló el análisis y la determinación de la mutagenicidad y genotoxicidad en aguas residuales de la curtiembre Tasajero. Para la determinación de la genotoxicidad, se usó el ensayo cometa y para el análisis de la mutagenicidad, se aplicó el test de Ames, con las cepas de Salmonella typhimurium TA98 y TA100. Se encontró que las aguas de desecho de la curtiembre Tasajero inducen daño al ADN en linfocitos humanos; de igual manera, se halló que estas aguas también inducen un incremento en la mutagenicidad en la cepa TA98. Universidad de Ciencias Aplicadas y Ambientales U.D.C.A 2015-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/html https://revistas.udca.edu.co/index.php/ruadc/article/view/449 10.31910/rudca.v18.n1.2015.449 Revista U.D.C.A Actualidad & Divulgación Científica; Vol. 18 No. 1 (2015): Revista U.D.C.A Actualidad & Divulgación Científica. Enero-Junio; 13-20 Revista U.D.C.A Actualidad & Divulgación Científica; Vol. 18 Núm. 1 (2015): Revista U.D.C.A Actualidad & Divulgación Científica. Enero-Junio; 13-20 Revista U.D.C.A Actualidad & Divulgación Científica; v. 18 n. 1 (2015): Revista U.D.C.A Actualidad & Divulgación Científica. Enero-Junio; 13-20 2619-2551 0123-4226 10.31910/rudca.v18.n1.2015 spa https://revistas.udca.edu.co/index.php/ruadc/article/view/449/377 https://revistas.udca.edu.co/index.php/ruadc/article/view/449/1238 /*ref*/ACHARYA, S.; MEHTA, K.; KRISHNAN, S.; RAO, C.V. 2001. A subtoxic interactive toxicity study of ethanol and chromium in male Wistar rats. Alcohol. 23:99- 108. /*ref*/AGENCY FOR TOXIC SUBSTANCES and DISEASE REGISTRY (ATSDR). 2000. Toxicological profile for Polychlorinated Biphenyls (PCBs). p.1-92. /*ref*/ALBERG, A.J.; SAMET, J.M. 2003. Epidemiology of lung cancer. Chest. 123(1 Suppl):21S-49S. /*ref*/ÁLVAREZ–BERNAL, D.; CONTRERAS-RAMOS, S.M.; TRUJILLO-TAPIA, N.; OLALDE-PORTUGAL, V.; FRIAS-HERNANDEZ, J.T.; DENDOOVEN, L. 2006. Effects of tanneries wastewater on chemical and biological soil characteristics. Appl. Soil Ecology. 33:269-277. /*ref*/AMES, B.N.; LEE, F.D.; DURSTON, W.E. 1973. 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