Reduction and sterilization of eggs of gastrointestinal nematodes in goats dewormed with benzimidazoles anthelmintics
The ovicide activity, “in vivo”, of the benzimidazoles: oxfendazole, fenbendazole, albendazole and thiabendazole on caprine gastrointestinal nematodes was determined and compared. Female goats naturally infected with gastrintestinal nematodes were medicated with oxfendazole (435 mg/kg), fenbendazole (5.0 mg/kg), albendazole (3.8 mg/kg) and thiabendazole (44.0 mg/kg). Feces were collected from the rectum to determine the number of eggs per gram (EPG) and to make fecal cultures, before medication and at subsequent periods from three to twelve hours after medication. Afterwards, collections were performed at intervals of 12 to 168 hours. Thiabendazole showed good activity on the reduction and sterilization of Strongyloides eggs but did not show the same activity against Haemonchus and Oesophagostomum. Oxfendazole, fenbendazole, and albendazole had good activity on the reduction and sterilization of the eggs of Trichostrongylus and Oesophagostomum, but did not have the same activity on Haemonchus and Strongyloides. Oxfendazole and thiabendazole were the only benzimidazoles that curbed the development and multiplication of the free living female Strongyloides in fecal cultures of dewormed animals.
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Pesquisa Agropecuaria Brasileira
2014
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rev-pab-br-article-164592014-08-29T17:21:57Z Reduction and sterilization of eggs of gastrointestinal nematodes in goats dewormed with benzimidazoles anthelmintics Redução e esterilização de ovos do nematódeos gastrintestinais em caprinos medicados com anti-helmínticos benzimidazóis Vieira, Luiz da Silva Gonçalves, Pedro Cabral Costa, Carlos Alberto Fagonde Berne, Maria Elisabeth Aires oxfendazole; fenbendazole; albendazole; fecal cultures; Strongyloides; Haemonchus; Oesophagostomum; Trichostrongylus. oxfendazole; fenbendazole; albendazole; thiabendazole; coproculturas; Strongyloides; Haemonchus; Oesophagostomum; Trichostrongylus. The ovicide activity, “in vivo”, of the benzimidazoles: oxfendazole, fenbendazole, albendazole and thiabendazole on caprine gastrointestinal nematodes was determined and compared. Female goats naturally infected with gastrintestinal nematodes were medicated with oxfendazole (435 mg/kg), fenbendazole (5.0 mg/kg), albendazole (3.8 mg/kg) and thiabendazole (44.0 mg/kg). Feces were collected from the rectum to determine the number of eggs per gram (EPG) and to make fecal cultures, before medication and at subsequent periods from three to twelve hours after medication. Afterwards, collections were performed at intervals of 12 to 168 hours. Thiabendazole showed good activity on the reduction and sterilization of Strongyloides eggs but did not show the same activity against Haemonchus and Oesophagostomum. Oxfendazole, fenbendazole, and albendazole had good activity on the reduction and sterilization of the eggs of Trichostrongylus and Oesophagostomum, but did not have the same activity on Haemonchus and Strongyloides. Oxfendazole and thiabendazole were the only benzimidazoles that curbed the development and multiplication of the free living female Strongyloides in fecal cultures of dewormed animals. Determinou-se a atividade ovicida "in vivo" e também a duração da mesma dos benzimidazóis: oxfendazole, fenbendazole, albendazole e thiabendazole em nematódeos gastrintestinais de caprinos. Cabras naturalmente infectadas com nematódeos gastrintestinais foram medicadas com oxfendazole (4,75 mg/kg),fenbendazole (5,0 mg/kg) e thiabendazole (44,0 mg/kg). Realizaram-se coletas de fezes diretamente da ampola retal para determinação do número de ovos por grama de fezes (OPG) e realização de coproculturas, antes do tratamento e em períodos subsequentes de três até doze horas após o tratamento. Posteriormente, as coletas passaram a ser realizadas com intervalos de 12 até 168 horas. O thiabendazole mostrou boa atividade na redução e esterilização de ovos de Strongyloides, ocorrendo o inverso com relação ao Haemonchus e Oesophagostomum. O oxfendazole, fenbendazole e albendazole apresentaram boa atividade na redução e esterilização de ovos de Trichostrongylus, não tendo a mesma atividade em Haemonchus e Strongyloides. O oxfendazole e o thiabendazole foram os únicos benzimidazóis que impediram o desenvolvimento e a multiplicação de fêmeas de Strongyloides de vida livre nas coproculturas dos animais vermifugados. Pesquisa Agropecuaria Brasileira Pesquisa Agropecuária Brasileira 2014-04-17 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://seer.sct.embrapa.br/index.php/pab/article/view/16459 Pesquisa Agropecuaria Brasileira; v.24, n.10, out. 1989; 1255-1265 Pesquisa Agropecuária Brasileira; v.24, n.10, out. 1989; 1255-1265 1678-3921 0100-104x por https://seer.sct.embrapa.br/index.php/pab/article/view/16459/10724 |
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Vieira, Luiz da Silva Gonçalves, Pedro Cabral Costa, Carlos Alberto Fagonde Berne, Maria Elisabeth Aires |
| spellingShingle |
Vieira, Luiz da Silva Gonçalves, Pedro Cabral Costa, Carlos Alberto Fagonde Berne, Maria Elisabeth Aires Reduction and sterilization of eggs of gastrointestinal nematodes in goats dewormed with benzimidazoles anthelmintics |
| author_facet |
Vieira, Luiz da Silva Gonçalves, Pedro Cabral Costa, Carlos Alberto Fagonde Berne, Maria Elisabeth Aires |
| author_sort |
Vieira, Luiz da Silva |
| title |
Reduction and sterilization of eggs of gastrointestinal nematodes in goats dewormed with benzimidazoles anthelmintics |
| title_short |
Reduction and sterilization of eggs of gastrointestinal nematodes in goats dewormed with benzimidazoles anthelmintics |
| title_full |
Reduction and sterilization of eggs of gastrointestinal nematodes in goats dewormed with benzimidazoles anthelmintics |
| title_fullStr |
Reduction and sterilization of eggs of gastrointestinal nematodes in goats dewormed with benzimidazoles anthelmintics |
| title_full_unstemmed |
Reduction and sterilization of eggs of gastrointestinal nematodes in goats dewormed with benzimidazoles anthelmintics |
| title_sort |
reduction and sterilization of eggs of gastrointestinal nematodes in goats dewormed with benzimidazoles anthelmintics |
| description |
The ovicide activity, “in vivo”, of the benzimidazoles: oxfendazole, fenbendazole, albendazole and thiabendazole on caprine gastrointestinal nematodes was determined and compared. Female goats naturally infected with gastrintestinal nematodes were medicated with oxfendazole (435 mg/kg), fenbendazole (5.0 mg/kg), albendazole (3.8 mg/kg) and thiabendazole (44.0 mg/kg). Feces were collected from the rectum to determine the number of eggs per gram (EPG) and to make fecal cultures, before medication and at subsequent periods from three to twelve hours after medication. Afterwards, collections were performed at intervals of 12 to 168 hours. Thiabendazole showed good activity on the reduction and sterilization of Strongyloides eggs but did not show the same activity against Haemonchus and Oesophagostomum. Oxfendazole, fenbendazole, and albendazole had good activity on the reduction and sterilization of the eggs of Trichostrongylus and Oesophagostomum, but did not have the same activity on Haemonchus and Strongyloides. Oxfendazole and thiabendazole were the only benzimidazoles that curbed the development and multiplication of the free living female Strongyloides in fecal cultures of dewormed animals. |
| publisher |
Pesquisa Agropecuaria Brasileira |
| publishDate |
2014 |
| url |
https://seer.sct.embrapa.br/index.php/pab/article/view/16459 |
| work_keys_str_mv |
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