Retrospective seroepidemiological study of small ruminant lentivirus, paratuberculosis and brucellosis in goats from Mexico, based on multiplex assay

Mexican goat production systems face infection risks from Brucella melitensis, small ruminant lentivirus (SRLv) and Mycobacterium avium subsp. paratuberculosis (MAP); agents that cause great economic losses and directly affect public health (brucellosis and paratuberculosis [PTb]). Currently, there are no diagnostic tests applicable at large scale nor epidemiological information regarding the seroprevalence for these infectious diseases. For this study, a multiplex antibody assay (Luminex®) was used to retrospectively study the seroprevalence of brucellosis, SRLv, and PTb in the sera of 983 goats from nine Mexican states. Sera were obtained between 2014 and 2019. Antibodies against all three infectious diseases were detected in almost all tested samples. The estimated seroprevalence values ranged from 37% to 78% for brucellosis, 21% to 65% for SRLv, and 0% to 13% for PTb. The multiplex assay (Luminex®) is a simple, accessible, efficient, and cost-effective seroprevalence monitoring tool for brucellosis, SRLv, and PTb, and can be used as a large-scale approach.

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Main Authors: Rodríguez-Cortez, Ana Delia, Montoya-Carrillo, Cecilia, Nájera-Rivera, Héctor Daniel, Zaldivar-Gómez, Alejandro, Herrera-Lopez, Enrique, Rico-Chavez, Oscar, Ramírez-Álvarez, Hugo, De-Las-Peñas, Alejandro, Díaz-Aparicio, Efrén, Cobos-Marin, Laura
Format: Digital revista
Language:eng
Published: Faculty of Veterinary Sciences - Universidad Austral de Chile 2024
Online Access:http://revistas.uach.cl/index.php/australjvs/article/view/7574
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spelling rev-australjvs-cl-article-75742024-10-04T18:37:10Z Retrospective seroepidemiological study of small ruminant lentivirus, paratuberculosis and brucellosis in goats from Mexico, based on multiplex assay Rodríguez-Cortez, Ana Delia Montoya-Carrillo, Cecilia Nájera-Rivera, Héctor Daniel Zaldivar-Gómez, Alejandro Herrera-Lopez, Enrique Rico-Chavez, Oscar Ramírez-Álvarez, Hugo De-Las-Peñas, Alejandro Díaz-Aparicio, Efrén Cobos-Marin, Laura Caprine diagnostic antibodies Luminex ® serological Mexican goat production systems face infection risks from Brucella melitensis, small ruminant lentivirus (SRLv) and Mycobacterium avium subsp. paratuberculosis (MAP); agents that cause great economic losses and directly affect public health (brucellosis and paratuberculosis [PTb]). Currently, there are no diagnostic tests applicable at large scale nor epidemiological information regarding the seroprevalence for these infectious diseases. For this study, a multiplex antibody assay (Luminex®) was used to retrospectively study the seroprevalence of brucellosis, SRLv, and PTb in the sera of 983 goats from nine Mexican states. Sera were obtained between 2014 and 2019. Antibodies against all three infectious diseases were detected in almost all tested samples. The estimated seroprevalence values ranged from 37% to 78% for brucellosis, 21% to 65% for SRLv, and 0% to 13% for PTb. The multiplex assay (Luminex®) is a simple, accessible, efficient, and cost-effective seroprevalence monitoring tool for brucellosis, SRLv, and PTb, and can be used as a large-scale approach. Faculty of Veterinary Sciences - Universidad Austral de Chile 2024-06-10 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf http://revistas.uach.cl/index.php/australjvs/article/view/7574 10.4206/ajvs.562.02 Austral Journal of Veterinary Sciences; Vol. 56 No. 2 (2024); 59-66 Austral Journal of Veterinary Sciences; Vol. 56 Núm. 2 (2024); 59-66 0719-8132 0719-8000 eng http://revistas.uach.cl/index.php/australjvs/article/view/7574/8595
institution UACH CL
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country Chile
countrycode CL
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databasecode rev-australjvs-cl
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region America del Sur
libraryname Biblioteca de la Facultad de Ciencias Veterinarias de la UACH
language eng
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author Rodríguez-Cortez, Ana Delia
Montoya-Carrillo, Cecilia
Nájera-Rivera, Héctor Daniel
Zaldivar-Gómez, Alejandro
Herrera-Lopez, Enrique
Rico-Chavez, Oscar
Ramírez-Álvarez, Hugo
De-Las-Peñas, Alejandro
Díaz-Aparicio, Efrén
Cobos-Marin, Laura
spellingShingle Rodríguez-Cortez, Ana Delia
Montoya-Carrillo, Cecilia
Nájera-Rivera, Héctor Daniel
Zaldivar-Gómez, Alejandro
Herrera-Lopez, Enrique
Rico-Chavez, Oscar
Ramírez-Álvarez, Hugo
De-Las-Peñas, Alejandro
Díaz-Aparicio, Efrén
Cobos-Marin, Laura
Retrospective seroepidemiological study of small ruminant lentivirus, paratuberculosis and brucellosis in goats from Mexico, based on multiplex assay
author_facet Rodríguez-Cortez, Ana Delia
Montoya-Carrillo, Cecilia
Nájera-Rivera, Héctor Daniel
Zaldivar-Gómez, Alejandro
Herrera-Lopez, Enrique
Rico-Chavez, Oscar
Ramírez-Álvarez, Hugo
De-Las-Peñas, Alejandro
Díaz-Aparicio, Efrén
Cobos-Marin, Laura
author_sort Rodríguez-Cortez, Ana Delia
title Retrospective seroepidemiological study of small ruminant lentivirus, paratuberculosis and brucellosis in goats from Mexico, based on multiplex assay
title_short Retrospective seroepidemiological study of small ruminant lentivirus, paratuberculosis and brucellosis in goats from Mexico, based on multiplex assay
title_full Retrospective seroepidemiological study of small ruminant lentivirus, paratuberculosis and brucellosis in goats from Mexico, based on multiplex assay
title_fullStr Retrospective seroepidemiological study of small ruminant lentivirus, paratuberculosis and brucellosis in goats from Mexico, based on multiplex assay
title_full_unstemmed Retrospective seroepidemiological study of small ruminant lentivirus, paratuberculosis and brucellosis in goats from Mexico, based on multiplex assay
title_sort retrospective seroepidemiological study of small ruminant lentivirus, paratuberculosis and brucellosis in goats from mexico, based on multiplex assay
description Mexican goat production systems face infection risks from Brucella melitensis, small ruminant lentivirus (SRLv) and Mycobacterium avium subsp. paratuberculosis (MAP); agents that cause great economic losses and directly affect public health (brucellosis and paratuberculosis [PTb]). Currently, there are no diagnostic tests applicable at large scale nor epidemiological information regarding the seroprevalence for these infectious diseases. For this study, a multiplex antibody assay (Luminex®) was used to retrospectively study the seroprevalence of brucellosis, SRLv, and PTb in the sera of 983 goats from nine Mexican states. Sera were obtained between 2014 and 2019. Antibodies against all three infectious diseases were detected in almost all tested samples. The estimated seroprevalence values ranged from 37% to 78% for brucellosis, 21% to 65% for SRLv, and 0% to 13% for PTb. The multiplex assay (Luminex®) is a simple, accessible, efficient, and cost-effective seroprevalence monitoring tool for brucellosis, SRLv, and PTb, and can be used as a large-scale approach.
publisher Faculty of Veterinary Sciences - Universidad Austral de Chile
publishDate 2024
url http://revistas.uach.cl/index.php/australjvs/article/view/7574
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