Acral subungual lentiginous melanoma: The importance of early diagnosis and treatment

Abstract Acral lentiginous melanoma is uncommon, representing about 4–6% of all melanomas that affect the Caucasian population, but it is the most frequent form of melanoma in Asian and African descendants, with a prevalence above 50%. Peak of incidence is around the sixth decade of life and affects both sexes equally. The etiology is uncertain, but it is suspected that local trauma and traumatic stress are part of the possible triggering factors. Onychomycosis, subungual hematoma, and striated melanonychia generated by a nevus in the nail matrix are part of the differential diagnosis. We present the case of a young patient with melanonychia in the first right finger, with recent onset and progressive alteration, both in color and in the width of the melanonychia, whose histopathology confirmed the diagnosis of subungual melanoma in situ. A surgical approach with removal of the nail apparatus and conservation of the distal phalanx has been successful with no relapse after two years.

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Main Authors: Davanço,Rodrigo César, Amaro,Rafael, Neto,Domingos Jordão, Milanez,Carolina Brandão, Rezende,Aline Sperandio Porto
Format: Digital revista
Language:English
Published: Permanyer Publications 2022
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012022000200151
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spelling oai:scielo:S2795-500120220002001512024-02-06Acral subungual lentiginous melanoma: The importance of early diagnosis and treatmentDavanço,Rodrigo CésarAmaro,RafaelNeto,Domingos JordãoMilanez,Carolina BrandãoRezende,Aline Sperandio Porto Melanoma MART-1 antigen Nevi and melanoma Abstract Acral lentiginous melanoma is uncommon, representing about 4–6% of all melanomas that affect the Caucasian population, but it is the most frequent form of melanoma in Asian and African descendants, with a prevalence above 50%. Peak of incidence is around the sixth decade of life and affects both sexes equally. The etiology is uncertain, but it is suspected that local trauma and traumatic stress are part of the possible triggering factors. Onychomycosis, subungual hematoma, and striated melanonychia generated by a nevus in the nail matrix are part of the differential diagnosis. We present the case of a young patient with melanonychia in the first right finger, with recent onset and progressive alteration, both in color and in the width of the melanonychia, whose histopathology confirmed the diagnosis of subungual melanoma in situ. A surgical approach with removal of the nail apparatus and conservation of the distal phalanx has been successful with no relapse after two years.info:eu-repo/semantics/openAccessPermanyer PublicationsPortuguese Journal of Dermatology and Venereology v.80 n.2 20222022-06-01info:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012022000200151en10.24875/pjd.m22000018
institution SCIELO
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country Portugal
countrycode PT
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region Europa del Sur
libraryname SciELO
language English
format Digital
author Davanço,Rodrigo César
Amaro,Rafael
Neto,Domingos Jordão
Milanez,Carolina Brandão
Rezende,Aline Sperandio Porto
spellingShingle Davanço,Rodrigo César
Amaro,Rafael
Neto,Domingos Jordão
Milanez,Carolina Brandão
Rezende,Aline Sperandio Porto
Acral subungual lentiginous melanoma: The importance of early diagnosis and treatment
author_facet Davanço,Rodrigo César
Amaro,Rafael
Neto,Domingos Jordão
Milanez,Carolina Brandão
Rezende,Aline Sperandio Porto
author_sort Davanço,Rodrigo César
title Acral subungual lentiginous melanoma: The importance of early diagnosis and treatment
title_short Acral subungual lentiginous melanoma: The importance of early diagnosis and treatment
title_full Acral subungual lentiginous melanoma: The importance of early diagnosis and treatment
title_fullStr Acral subungual lentiginous melanoma: The importance of early diagnosis and treatment
title_full_unstemmed Acral subungual lentiginous melanoma: The importance of early diagnosis and treatment
title_sort acral subungual lentiginous melanoma: the importance of early diagnosis and treatment
description Abstract Acral lentiginous melanoma is uncommon, representing about 4–6% of all melanomas that affect the Caucasian population, but it is the most frequent form of melanoma in Asian and African descendants, with a prevalence above 50%. Peak of incidence is around the sixth decade of life and affects both sexes equally. The etiology is uncertain, but it is suspected that local trauma and traumatic stress are part of the possible triggering factors. Onychomycosis, subungual hematoma, and striated melanonychia generated by a nevus in the nail matrix are part of the differential diagnosis. We present the case of a young patient with melanonychia in the first right finger, with recent onset and progressive alteration, both in color and in the width of the melanonychia, whose histopathology confirmed the diagnosis of subungual melanoma in situ. A surgical approach with removal of the nail apparatus and conservation of the distal phalanx has been successful with no relapse after two years.
publisher Permanyer Publications
publishDate 2022
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2795-50012022000200151
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