Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?

Abstract Introduction: Kidney transplantation is the treatment of choice for end-stage renal disease (ESRD). Since March 2020, transplant activity in Mexico has been affected due to the COVID-19 pandemic. Objective: The aim of the study was to determine the impact on mortality of patients on the waiting list (WL) for cadaveric donor kidney transplantation in a referral hospital in Yucatán, due to suspension of activities due to the pandemic. Material and methods: Patients over 18 years of age on the waiting list for kidney transplantation at this hospital. In the event of a patient's death, the cause was investigated, especially if it was associated with COVID-19. A two-tailed p ≤ 0.05 was considered significant in all analyzes. Results: The odds ratio (OR) of death from COVID-19 in a patient with ESRD in the WL in 2020 was OR = 5.04 (95% CI: 1.65-7.14, p = 0.023). The OR of dying with ESRD in the WL with a delay in the follow-up visits was OR = 6.59 (95% CI: 2.7-16.28, p = 0.008). Conclusion: The probability of death of a patient with ESRD with delayed follow-up visits and transplant retention is statistically higher than the probability of death from COVID-19.

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Main Authors: Martínez-Ulloa-Torres,Jorge, Gutiérrez-Torres,Paulo, Castro-Ruiz,Pablo, Bolado-García,Patricia B., Hernandez-Dominguez,Mariano, Aguilar-Castillejos,Luis F., Tun-Abraham,Mauro E., Baas-Cruz,Juan P.
Format: Digital revista
Language:English
Published: Academia Mexicana de Cirugía A.C. 2023
Online Access:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2444-054X2023000400507
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spelling oai:scielo:S2444-054X20230004005072023-10-27Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?Martínez-Ulloa-Torres,JorgeGutiérrez-Torres,PauloCastro-Ruiz,PabloBolado-García,Patricia B.Hernandez-Dominguez,MarianoAguilar-Castillejos,Luis F.Tun-Abraham,Mauro E.Baas-Cruz,Juan P. COVID-19 End stage renal disease Kidney transplant Waiting list mortality Abstract Introduction: Kidney transplantation is the treatment of choice for end-stage renal disease (ESRD). Since March 2020, transplant activity in Mexico has been affected due to the COVID-19 pandemic. Objective: The aim of the study was to determine the impact on mortality of patients on the waiting list (WL) for cadaveric donor kidney transplantation in a referral hospital in Yucatán, due to suspension of activities due to the pandemic. Material and methods: Patients over 18 years of age on the waiting list for kidney transplantation at this hospital. In the event of a patient's death, the cause was investigated, especially if it was associated with COVID-19. A two-tailed p ≤ 0.05 was considered significant in all analyzes. Results: The odds ratio (OR) of death from COVID-19 in a patient with ESRD in the WL in 2020 was OR = 5.04 (95% CI: 1.65-7.14, p = 0.023). The OR of dying with ESRD in the WL with a delay in the follow-up visits was OR = 6.59 (95% CI: 2.7-16.28, p = 0.008). Conclusion: The probability of death of a patient with ESRD with delayed follow-up visits and transplant retention is statistically higher than the probability of death from COVID-19.info:eu-repo/semantics/openAccessAcademia Mexicana de Cirugía A.C.Cirugía y cirujanos v.91 n.4 20232023-08-01info:eu-repo/semantics/articletext/htmlhttp://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2444-054X2023000400507en10.24875/ciru.21000718
institution SCIELO
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country México
countrycode MX
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databasecode rev-scielo-mx
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region America del Norte
libraryname SciELO
language English
format Digital
author Martínez-Ulloa-Torres,Jorge
Gutiérrez-Torres,Paulo
Castro-Ruiz,Pablo
Bolado-García,Patricia B.
Hernandez-Dominguez,Mariano
Aguilar-Castillejos,Luis F.
Tun-Abraham,Mauro E.
Baas-Cruz,Juan P.
spellingShingle Martínez-Ulloa-Torres,Jorge
Gutiérrez-Torres,Paulo
Castro-Ruiz,Pablo
Bolado-García,Patricia B.
Hernandez-Dominguez,Mariano
Aguilar-Castillejos,Luis F.
Tun-Abraham,Mauro E.
Baas-Cruz,Juan P.
Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?
author_facet Martínez-Ulloa-Torres,Jorge
Gutiérrez-Torres,Paulo
Castro-Ruiz,Pablo
Bolado-García,Patricia B.
Hernandez-Dominguez,Mariano
Aguilar-Castillejos,Luis F.
Tun-Abraham,Mauro E.
Baas-Cruz,Juan P.
author_sort Martínez-Ulloa-Torres,Jorge
title Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?
title_short Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?
title_full Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?
title_fullStr Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?
title_full_unstemmed Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?
title_sort renal transplant waiting list mortality in covid era: is it advisable to halt transplant activity?
description Abstract Introduction: Kidney transplantation is the treatment of choice for end-stage renal disease (ESRD). Since March 2020, transplant activity in Mexico has been affected due to the COVID-19 pandemic. Objective: The aim of the study was to determine the impact on mortality of patients on the waiting list (WL) for cadaveric donor kidney transplantation in a referral hospital in Yucatán, due to suspension of activities due to the pandemic. Material and methods: Patients over 18 years of age on the waiting list for kidney transplantation at this hospital. In the event of a patient's death, the cause was investigated, especially if it was associated with COVID-19. A two-tailed p ≤ 0.05 was considered significant in all analyzes. Results: The odds ratio (OR) of death from COVID-19 in a patient with ESRD in the WL in 2020 was OR = 5.04 (95% CI: 1.65-7.14, p = 0.023). The OR of dying with ESRD in the WL with a delay in the follow-up visits was OR = 6.59 (95% CI: 2.7-16.28, p = 0.008). Conclusion: The probability of death of a patient with ESRD with delayed follow-up visits and transplant retention is statistically higher than the probability of death from COVID-19.
publisher Academia Mexicana de Cirugía A.C.
publishDate 2023
url http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2444-054X2023000400507
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