Effect of Re-TUR time on recurrence and progression in high-risk non-muscle-invasive bladder cancer

Abstract Objective: We aimed to investigate the significance of time to re-staging transurethral resection (re-TUR) on recurrence and progression rates in patients with high-risk non-muscle-invasive bladder cancer as a prospective randomized study. Methods: The patients were randomly separated into three groups according to Re-TUR timing. In Groups 1, 2, and 3, the time interval between initial and re-TUR was 14-28 days, 29-42 days, and 43-56 days, respectively. Cox regression analysis was used to assess the effect of time from initial TUR to re-TUR on oncological outcomes. Results: Twenty patients in Group 1 (14-28 days), 22 patients in Group 2 (29-42 days), and 29 patients in Group 3 (43-56 days) completed the study. Kaplan–Meier plots showed no differences in recurrence-free survival (RFS) and progression-free survival (PFS) rates between the three groups. Cox regression analysis demonstrated that only tumor number was found to be a prognostic factor on RFS rates. Conclusion: Our prospective study demonstrated that time laps from initial TUR to re-TUR did not significantly affect on RFS and PFS rates.

Bibliographic Details

Main Authors:	Demir,Demirhan O., Doluoglu,Omer G., Yildiz,Ali K., Kacan,Turgay, Yazar,Veli M., Demirbas,Arif, Ozgur,Berat C.
Format:	Digital revista
Language:	English
Published:	Academia Mexicana de Cirugía A.C. 2022
Online Access:	http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S2444-054X2022000800006
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