Takayasu Arteritis as a Secondary Cause of Arterial Hypertension
Abstract Takayasu arteritis (TA) is a rare type of vasculitis that affects mainly the aorta and its major branches. It is highly similar to giant cell arteritis (GCA), and differentiation between them may not be achieved even by histological examination. Arterial hypertension is typical of TA and is caused by stenosis of the renal arteries. Here we report the case of a 59-year-old woman, with a history of dyslipidemia and anemia, seen in the Internal Medicine department for resistant hypertension. Evaluation of secondary causes led to stenosis of the renal arteries. Assessment of target organ involvement was performed by computed tomography angiograph which revealed ectasia of the aortic arch and ascending aorta, tortuous course of the brachiocephalic trunk and the proximal portion of the right common carotid artery; positron-emission tomography which showed diffuse increased uptake in the ascending aorta, compatible with large vessels vasculitis. The patient was submitted to aortic valve replacement with a biological prosthesis combined with myocardial revascularization (Bentall-De Bono procedure). Aortic biopsy specimens showed anatomical and pathological features of GCA and TA. Due to persistently uncontrolled hypertension, prednisone 60 mg was initiated,with significant improvement in patient’s condition.
Main Authors: | , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Cardiologia
2023
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472023000100502 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
id |
oai:scielo:S2359-56472023000100502 |
---|---|
record_format |
ojs |
spelling |
oai:scielo:S2359-564720230001005022023-01-24Takayasu Arteritis as a Secondary Cause of Arterial HypertensionOliveira,Pedro ManuelFereira,PaulaMurteira,FábioRato,Inês RueffBarbedo,Marta Takayasu Arteritis Hypertension Renal Artery Obstruction Aorta, Thoracic Computed Tomography Angiography/ methods Abstract Takayasu arteritis (TA) is a rare type of vasculitis that affects mainly the aorta and its major branches. It is highly similar to giant cell arteritis (GCA), and differentiation between them may not be achieved even by histological examination. Arterial hypertension is typical of TA and is caused by stenosis of the renal arteries. Here we report the case of a 59-year-old woman, with a history of dyslipidemia and anemia, seen in the Internal Medicine department for resistant hypertension. Evaluation of secondary causes led to stenosis of the renal arteries. Assessment of target organ involvement was performed by computed tomography angiograph which revealed ectasia of the aortic arch and ascending aorta, tortuous course of the brachiocephalic trunk and the proximal portion of the right common carotid artery; positron-emission tomography which showed diffuse increased uptake in the ascending aorta, compatible with large vessels vasculitis. The patient was submitted to aortic valve replacement with a biological prosthesis combined with myocardial revascularization (Bentall-De Bono procedure). Aortic biopsy specimens showed anatomical and pathological features of GCA and TA. Due to persistently uncontrolled hypertension, prednisone 60 mg was initiated,with significant improvement in patient’s condition.info:eu-repo/semantics/openAccessSociedade Brasileira de CardiologiaInternational Journal of Cardiovascular Sciences v.36 20232023-01-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472023000100502en10.36660/ijcs.20210040 |
institution |
SCIELO |
collection |
OJS |
country |
Brasil |
countrycode |
BR |
component |
Revista |
access |
En linea |
databasecode |
rev-scielo-br |
tag |
revista |
region |
America del Sur |
libraryname |
SciELO |
language |
English |
format |
Digital |
author |
Oliveira,Pedro Manuel Fereira,Paula Murteira,Fábio Rato,Inês Rueff Barbedo,Marta |
spellingShingle |
Oliveira,Pedro Manuel Fereira,Paula Murteira,Fábio Rato,Inês Rueff Barbedo,Marta Takayasu Arteritis as a Secondary Cause of Arterial Hypertension |
author_facet |
Oliveira,Pedro Manuel Fereira,Paula Murteira,Fábio Rato,Inês Rueff Barbedo,Marta |
author_sort |
Oliveira,Pedro Manuel |
title |
Takayasu Arteritis as a Secondary Cause of Arterial Hypertension |
title_short |
Takayasu Arteritis as a Secondary Cause of Arterial Hypertension |
title_full |
Takayasu Arteritis as a Secondary Cause of Arterial Hypertension |
title_fullStr |
Takayasu Arteritis as a Secondary Cause of Arterial Hypertension |
title_full_unstemmed |
Takayasu Arteritis as a Secondary Cause of Arterial Hypertension |
title_sort |
takayasu arteritis as a secondary cause of arterial hypertension |
description |
Abstract Takayasu arteritis (TA) is a rare type of vasculitis that affects mainly the aorta and its major branches. It is highly similar to giant cell arteritis (GCA), and differentiation between them may not be achieved even by histological examination. Arterial hypertension is typical of TA and is caused by stenosis of the renal arteries. Here we report the case of a 59-year-old woman, with a history of dyslipidemia and anemia, seen in the Internal Medicine department for resistant hypertension. Evaluation of secondary causes led to stenosis of the renal arteries. Assessment of target organ involvement was performed by computed tomography angiograph which revealed ectasia of the aortic arch and ascending aorta, tortuous course of the brachiocephalic trunk and the proximal portion of the right common carotid artery; positron-emission tomography which showed diffuse increased uptake in the ascending aorta, compatible with large vessels vasculitis. The patient was submitted to aortic valve replacement with a biological prosthesis combined with myocardial revascularization (Bentall-De Bono procedure). Aortic biopsy specimens showed anatomical and pathological features of GCA and TA. Due to persistently uncontrolled hypertension, prednisone 60 mg was initiated,with significant improvement in patient’s condition. |
publisher |
Sociedade Brasileira de Cardiologia |
publishDate |
2023 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472023000100502 |
work_keys_str_mv |
AT oliveirapedromanuel takayasuarteritisasasecondarycauseofarterialhypertension AT fereirapaula takayasuarteritisasasecondarycauseofarterialhypertension AT murteirafabio takayasuarteritisasasecondarycauseofarterialhypertension AT ratoinesrueff takayasuarteritisasasecondarycauseofarterialhypertension AT barbedomarta takayasuarteritisasasecondarycauseofarterialhypertension |
_version_ |
1756472642091614208 |