Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory Cardiomyopathy
Abstract A 72-year-old woman was admitted for acute heart failure. The echocardiography revealed moderate depression of the left ventricular ejection fraction. Coronary disease was excluded by coronarography. Cardiac magnetic resonance showed predominantly left ventricular septal hypertrophy and severe depression of the left ventricular systolic function. There was also a bright, multifocal and patchy late gadolinium enhancement with subendocardial, mesocardial and subepicardial involvement, suggestive of sarcoidosis. Biochemical study, thoracic computed tomography and positron emission tomography were inconclusive for extra-cardiac sarcoidosis. Therefore, an endomyocardial biopsy was performed. The procedure was complicated by the development of complete atrioventricular block, requiring implantation of a cardiac resynchronization pacing device. A few days after device implantation, the patient developed fever. The echocardiography revealed extensive vegetations, and thus the diagnosis of a device-associated infective endocarditis was made. Even though antibiotic therapy was promptly started, the patient ended up dying. Biopsy results revealed lymphocytic myocarditis. This case is paradigmatic because it shows how the etiologic diagnosis of dilated cardiomyopathy can be challenging. Non-invasive diagnostic exams may not provide a definite diagnosis, requiring an endomyocardial biopsy. However, the benefits versus risks of such procedure must always be carefully weighted.
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Sociedade Brasileira de Cardiologia
2020
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oai:scielo:S2359-564720200006007292020-11-23Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory CardiomyopathyAntunes,HugoGil,JúlioMarmelo,BrunoGonçalves,Maria LuísaPires,Maria InêsSantos,João MiguelCorreia,MiguelCabral,José Costa Iatrogenic Disease/complications Cardiomyopathies Diabetes Mellitus Hypertension Endocardites Cardiomyopathy, Dilated Spectroscopy, Magnetic Resonance/methods Abstract A 72-year-old woman was admitted for acute heart failure. The echocardiography revealed moderate depression of the left ventricular ejection fraction. Coronary disease was excluded by coronarography. Cardiac magnetic resonance showed predominantly left ventricular septal hypertrophy and severe depression of the left ventricular systolic function. There was also a bright, multifocal and patchy late gadolinium enhancement with subendocardial, mesocardial and subepicardial involvement, suggestive of sarcoidosis. Biochemical study, thoracic computed tomography and positron emission tomography were inconclusive for extra-cardiac sarcoidosis. Therefore, an endomyocardial biopsy was performed. The procedure was complicated by the development of complete atrioventricular block, requiring implantation of a cardiac resynchronization pacing device. A few days after device implantation, the patient developed fever. The echocardiography revealed extensive vegetations, and thus the diagnosis of a device-associated infective endocarditis was made. Even though antibiotic therapy was promptly started, the patient ended up dying. Biopsy results revealed lymphocytic myocarditis. This case is paradigmatic because it shows how the etiologic diagnosis of dilated cardiomyopathy can be challenging. Non-invasive diagnostic exams may not provide a definite diagnosis, requiring an endomyocardial biopsy. However, the benefits versus risks of such procedure must always be carefully weighted.info:eu-repo/semantics/openAccessSociedade Brasileira de CardiologiaInternational Journal of Cardiovascular Sciences v.33 n.6 20202020-12-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472020000600729en10.36660/ijcs.20190153 |
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Antunes,Hugo Gil,Júlio Marmelo,Bruno Gonçalves,Maria Luísa Pires,Maria Inês Santos,João Miguel Correia,Miguel Cabral,José Costa |
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Antunes,Hugo Gil,Júlio Marmelo,Bruno Gonçalves,Maria Luísa Pires,Maria Inês Santos,João Miguel Correia,Miguel Cabral,José Costa Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory Cardiomyopathy |
author_facet |
Antunes,Hugo Gil,Júlio Marmelo,Bruno Gonçalves,Maria Luísa Pires,Maria Inês Santos,João Miguel Correia,Miguel Cabral,José Costa |
author_sort |
Antunes,Hugo |
title |
Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory Cardiomyopathy |
title_short |
Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory Cardiomyopathy |
title_full |
Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory Cardiomyopathy |
title_fullStr |
Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory Cardiomyopathy |
title_full_unstemmed |
Iatrogenic Complications During the Diagnostic Work-Up of an Inflammatory Cardiomyopathy |
title_sort |
iatrogenic complications during the diagnostic work-up of an inflammatory cardiomyopathy |
description |
Abstract A 72-year-old woman was admitted for acute heart failure. The echocardiography revealed moderate depression of the left ventricular ejection fraction. Coronary disease was excluded by coronarography. Cardiac magnetic resonance showed predominantly left ventricular septal hypertrophy and severe depression of the left ventricular systolic function. There was also a bright, multifocal and patchy late gadolinium enhancement with subendocardial, mesocardial and subepicardial involvement, suggestive of sarcoidosis. Biochemical study, thoracic computed tomography and positron emission tomography were inconclusive for extra-cardiac sarcoidosis. Therefore, an endomyocardial biopsy was performed. The procedure was complicated by the development of complete atrioventricular block, requiring implantation of a cardiac resynchronization pacing device. A few days after device implantation, the patient developed fever. The echocardiography revealed extensive vegetations, and thus the diagnosis of a device-associated infective endocarditis was made. Even though antibiotic therapy was promptly started, the patient ended up dying. Biopsy results revealed lymphocytic myocarditis. This case is paradigmatic because it shows how the etiologic diagnosis of dilated cardiomyopathy can be challenging. Non-invasive diagnostic exams may not provide a definite diagnosis, requiring an endomyocardial biopsy. However, the benefits versus risks of such procedure must always be carefully weighted. |
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Sociedade Brasileira de Cardiologia |
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2020 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-56472020000600729 |
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