Postoperative calcium levels as a diagnostic measure for hypoparathyroidism after total thyroidectomy
ObjectiveThe aim of the present study was to identify a fast, efficient and low-cost method to diagnose hypoparathyroidism after total thyroidectomy.Materials and methodsOne hundred and forty medical records, which contained patients’ clinical and laboratory data, were retrospectively analyzed. Patient parathyroid hormone values, which were obtained immediately following operation, were compared with their ionized calcium levels the morning after surgery. This comparison was used to examine the correlation between the two variables in predicting hypoparathyroidism because measuring calcium levels is low-cost and more available in the hospitals compared to measuring parathormone (PTH) levels.ResultsThere was a positive and statistically significant correlation between PTH and ionized calcium values (Pearson correlation coefficient, r = 0.456; p < 0.0001). The values of first postoperative day ionized calcium levels (stratified by the 1.10 mmol/l cut-off value) were tested as a diagnostic measure for hypoparathyroidism, and a PTH < 15 pg/mL obtained immediately following operation served as a reference. This analysis showed that ionized calcium levels measured on the first postoperative day had a sensitivity of 45.6% (95% CI 30.9-61.0%), a specificity of 88.9% (95% CI 80.5-94.5%) and an accuracy of 76.7% (95% CI 68.7-83.5%) as a diagnostic measure for hypoparathyroidism.ConclusionIn conclusion, we demonstrated that patients who had high ionized calcium levels on the first postoperative day also had high PTH levels immediately following operation and, therefore, they had lower rates of hypoparathyroidism.
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Sociedade Brasileira de Endocrinologia e Metabologia
2015
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oai:scielo:S2359-399720150005004282015-10-30Postoperative calcium levels as a diagnostic measure for hypoparathyroidism after total thyroidectomyRosa,Karen ManoelaMatos,Leandro Luongo deCernea,Cláudio RobertoBrandão,Lenine GarciaAraújo Filho,Vergilius José Furtado de Thyroidectomy hypocalcemia hypoparathyroidism postoperative complications diagnosis ObjectiveThe aim of the present study was to identify a fast, efficient and low-cost method to diagnose hypoparathyroidism after total thyroidectomy.Materials and methodsOne hundred and forty medical records, which contained patients’ clinical and laboratory data, were retrospectively analyzed. Patient parathyroid hormone values, which were obtained immediately following operation, were compared with their ionized calcium levels the morning after surgery. This comparison was used to examine the correlation between the two variables in predicting hypoparathyroidism because measuring calcium levels is low-cost and more available in the hospitals compared to measuring parathormone (PTH) levels.ResultsThere was a positive and statistically significant correlation between PTH and ionized calcium values (Pearson correlation coefficient, r = 0.456; p < 0.0001). The values of first postoperative day ionized calcium levels (stratified by the 1.10 mmol/l cut-off value) were tested as a diagnostic measure for hypoparathyroidism, and a PTH < 15 pg/mL obtained immediately following operation served as a reference. This analysis showed that ionized calcium levels measured on the first postoperative day had a sensitivity of 45.6% (95% CI 30.9-61.0%), a specificity of 88.9% (95% CI 80.5-94.5%) and an accuracy of 76.7% (95% CI 68.7-83.5%) as a diagnostic measure for hypoparathyroidism.ConclusionIn conclusion, we demonstrated that patients who had high ionized calcium levels on the first postoperative day also had high PTH levels immediately following operation and, therefore, they had lower rates of hypoparathyroidism.info:eu-repo/semantics/openAccessSociedade Brasileira de Endocrinologia e MetabologiaArchives of Endocrinology and Metabolism v.59 n.5 20152015-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000500428en10.1590/2359-3997000000074 |
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Rosa,Karen Manoela Matos,Leandro Luongo de Cernea,Cláudio Roberto Brandão,Lenine Garcia Araújo Filho,Vergilius José Furtado de |
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Rosa,Karen Manoela Matos,Leandro Luongo de Cernea,Cláudio Roberto Brandão,Lenine Garcia Araújo Filho,Vergilius José Furtado de Postoperative calcium levels as a diagnostic measure for hypoparathyroidism after total thyroidectomy |
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Rosa,Karen Manoela Matos,Leandro Luongo de Cernea,Cláudio Roberto Brandão,Lenine Garcia Araújo Filho,Vergilius José Furtado de |
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Rosa,Karen Manoela |
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Postoperative calcium levels as a diagnostic measure for hypoparathyroidism after total thyroidectomy |
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Postoperative calcium levels as a diagnostic measure for hypoparathyroidism after total thyroidectomy |
title_full |
Postoperative calcium levels as a diagnostic measure for hypoparathyroidism after total thyroidectomy |
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Postoperative calcium levels as a diagnostic measure for hypoparathyroidism after total thyroidectomy |
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Postoperative calcium levels as a diagnostic measure for hypoparathyroidism after total thyroidectomy |
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postoperative calcium levels as a diagnostic measure for hypoparathyroidism after total thyroidectomy |
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ObjectiveThe aim of the present study was to identify a fast, efficient and low-cost method to diagnose hypoparathyroidism after total thyroidectomy.Materials and methodsOne hundred and forty medical records, which contained patients’ clinical and laboratory data, were retrospectively analyzed. Patient parathyroid hormone values, which were obtained immediately following operation, were compared with their ionized calcium levels the morning after surgery. This comparison was used to examine the correlation between the two variables in predicting hypoparathyroidism because measuring calcium levels is low-cost and more available in the hospitals compared to measuring parathormone (PTH) levels.ResultsThere was a positive and statistically significant correlation between PTH and ionized calcium values (Pearson correlation coefficient, r = 0.456; p < 0.0001). The values of first postoperative day ionized calcium levels (stratified by the 1.10 mmol/l cut-off value) were tested as a diagnostic measure for hypoparathyroidism, and a PTH < 15 pg/mL obtained immediately following operation served as a reference. This analysis showed that ionized calcium levels measured on the first postoperative day had a sensitivity of 45.6% (95% CI 30.9-61.0%), a specificity of 88.9% (95% CI 80.5-94.5%) and an accuracy of 76.7% (95% CI 68.7-83.5%) as a diagnostic measure for hypoparathyroidism.ConclusionIn conclusion, we demonstrated that patients who had high ionized calcium levels on the first postoperative day also had high PTH levels immediately following operation and, therefore, they had lower rates of hypoparathyroidism. |
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Sociedade Brasileira de Endocrinologia e Metabologia |
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2015 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2359-39972015000500428 |
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