Refractory Hidradenitis Suppurativa: A Diagnosis to Consider
Abstract Hidradenitis suppurativa is a chronic inflammatory disease associated with multiple comorbidities, and its association with lymphoma has recently been a topic of debate. However, it is still controversial whether this risk can be attributed to the disease itself or whether it has any relationship with immunosuppressive treatment. Here, we describe the case of a patient with severe perianal hidradenitis suppurativa treated with methotrexate and infliximab, whose exacerbation with persistence of severe symptoms refractory to adequate treatment led to the diagnosis of diffuse large non-Hodgkin B-cell lymphoma. It was decided to perform a colostomy to improve perianal sepsis, and immunochemotherapy was proposed.
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Sociedade Portuguesa de Gastrenterologia
2024
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oai:scielo:S2341-454520240001000602024-03-25Refractory Hidradenitis Suppurativa: A Diagnosis to ConsiderSaraiva,Rita OrnelasSaunders,ChristopherSantos,Margarida Varela dosCarvalho,DianaLoureiro,RafaelaRamos,Jaime Hidradenitis suppurativa Lymphoma Lymphoproliferative disorder Methotrexate Infliximab Abstract Hidradenitis suppurativa is a chronic inflammatory disease associated with multiple comorbidities, and its association with lymphoma has recently been a topic of debate. However, it is still controversial whether this risk can be attributed to the disease itself or whether it has any relationship with immunosuppressive treatment. Here, we describe the case of a patient with severe perianal hidradenitis suppurativa treated with methotrexate and infliximab, whose exacerbation with persistence of severe symptoms refractory to adequate treatment led to the diagnosis of diffuse large non-Hodgkin B-cell lymphoma. It was decided to perform a colostomy to improve perianal sepsis, and immunochemotherapy was proposed.info:eu-repo/semantics/openAccessSociedade Portuguesa de GastrenterologiaGE-Portuguese Journal of Gastroenterology v.31 n.1 20242024-02-01info:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452024000100060en10.1159/000528432 |
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Saraiva,Rita Ornelas Saunders,Christopher Santos,Margarida Varela dos Carvalho,Diana Loureiro,Rafaela Ramos,Jaime |
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Saraiva,Rita Ornelas Saunders,Christopher Santos,Margarida Varela dos Carvalho,Diana Loureiro,Rafaela Ramos,Jaime Refractory Hidradenitis Suppurativa: A Diagnosis to Consider |
author_facet |
Saraiva,Rita Ornelas Saunders,Christopher Santos,Margarida Varela dos Carvalho,Diana Loureiro,Rafaela Ramos,Jaime |
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Saraiva,Rita Ornelas |
title |
Refractory Hidradenitis Suppurativa: A Diagnosis to Consider |
title_short |
Refractory Hidradenitis Suppurativa: A Diagnosis to Consider |
title_full |
Refractory Hidradenitis Suppurativa: A Diagnosis to Consider |
title_fullStr |
Refractory Hidradenitis Suppurativa: A Diagnosis to Consider |
title_full_unstemmed |
Refractory Hidradenitis Suppurativa: A Diagnosis to Consider |
title_sort |
refractory hidradenitis suppurativa: a diagnosis to consider |
description |
Abstract Hidradenitis suppurativa is a chronic inflammatory disease associated with multiple comorbidities, and its association with lymphoma has recently been a topic of debate. However, it is still controversial whether this risk can be attributed to the disease itself or whether it has any relationship with immunosuppressive treatment. Here, we describe the case of a patient with severe perianal hidradenitis suppurativa treated with methotrexate and infliximab, whose exacerbation with persistence of severe symptoms refractory to adequate treatment led to the diagnosis of diffuse large non-Hodgkin B-cell lymphoma. It was decided to perform a colostomy to improve perianal sepsis, and immunochemotherapy was proposed. |
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Sociedade Portuguesa de Gastrenterologia |
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2024 |
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http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452024000100060 |
work_keys_str_mv |
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1794800866304196608 |