Differences between polydioxanone and poliglactin in intestinal anastomoses - a comparative study of intestinal anastomoses
ABSTRACT Introduction: Intestinal anastomosis is a surgical practice constantly realized by surgeons worldwide. When the option is to perform manual anastomosis, which is still widely used for its low cost, the question arises as to the best material to be applied. Objective: To compare polydioxanone and polyglactin threads for healing and tensile strength in intestinal anastomosis in rats. Method: We used 25 rats Wistar; after anesthesia, in groups A and B (10 rats each), laparotomy was performed, transection of the ileum at 5 and 10 cm proximally to the ileocecal valve; in group A, anastomosis was performed with 4 separate extra mucosal sutures with polidioxanone; in group B, anastomosis was performed with polyglactin; in group C (5 rats), laparotomy and manipulation of the ileum were performed. After 21 days, the animals were anesthetized and submitted to euthanasia. The specimens were sent for histopathological study and tensile strength analysis. Statistical analysis was performed using the Turkey and Student's t tests, with a significance of p < 0.05. Results: The results showed that in the tensile strength analysis, there were no significant differences between them. The histological analysis showed significant differences between the cicatrization pattern, where polydioxanone caused less fibrosis than polyglactin. Conclusion: Polydioxanone caused less fibrosis than polyglactin in intestinal anastomoses of rats.
Main Authors: | Santos,Carlos Henrique Marques dos, Santos Filho,Kerginaldo Gondim dos, Cassino,Pedro Carvalho, Chiquetti,Camila Vieira, Mello,Alvaro Pereira de, Dourado,Doroty Mesquita |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Coloproctologia
2017
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2237-93632017000400263 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The influence of methylene blue on the healing of intestinal anastomoses subjected to ischemia and reperfusion in rats
by: Miranda,Eron Fabio, et al.
Published: (2010) -
Cicatrização de anastomoses colônicas na vigência de obstrução intestinal: Estudo experimental em ratos
by: MT,Bezuti, et al.
Published: (2002) -
Estudo histomorfométrico de anastomoses primárias de cólon em coelhos, com e sem preparo intestinal
by: Torres Neto,Juvenal da Rocha, et al.
Published: (2007) -
Anastomose carótido-basilar
by: Reixach-Granés,Ricardo
Published: (1965) -
Estudo experimental sobre o uso de cianoacrilatos para anastomose intestinal látero-lateral em cães
by: Matera,Julia Maria, et al.
Published: (1999)