Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate

ABSTRACT Although uncommon in patients under oral therapy, bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be a very severe issue. Early intervention with surgical resection should be the preferable method of treating any stage of the disease, resulting in better outcomes and decreasing the morbidity of this condition. A 77-year-old female patient attended the Special Care Dentistry Centre of the University of São Paulo Faculty of Dentistry (CAPE FOUSP) complaining mainly of “an exposed bone that appeared after tooth extraction performed six months earlier”. The patient was diagnosed with osteonecrosis associated with bisphosphonate (sodium ibandronate) and surgically treated with removal of bone sequestration and antibiotic therapy. The patient was followed up for six years (a total of 6 appointments), presenting good general health and no sign of bone exposure. Imaging findings showed no changes related to BRONJ either.

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Main Authors: Figueiredo,Marília A., Medeiros,Frederico Buhatem, Ortega,Karem López
Format: Digital revista
Language:English
Published: Hospital Universitário da Universidade de São Paulo 2021
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602021000100700
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spelling oai:scielo:S2236-196020210001007002020-12-10Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonateFigueiredo,Marília A.Medeiros,Frederico BuhatemOrtega,Karem López Bisphosphonate-Related Osteonecrosis of the Jaw Ibandronic Acid Jaw Osteonecrosis ABSTRACT Although uncommon in patients under oral therapy, bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be a very severe issue. Early intervention with surgical resection should be the preferable method of treating any stage of the disease, resulting in better outcomes and decreasing the morbidity of this condition. A 77-year-old female patient attended the Special Care Dentistry Centre of the University of São Paulo Faculty of Dentistry (CAPE FOUSP) complaining mainly of “an exposed bone that appeared after tooth extraction performed six months earlier”. The patient was diagnosed with osteonecrosis associated with bisphosphonate (sodium ibandronate) and surgically treated with removal of bone sequestration and antibiotic therapy. The patient was followed up for six years (a total of 6 appointments), presenting good general health and no sign of bone exposure. Imaging findings showed no changes related to BRONJ either.info:eu-repo/semantics/openAccessHospital Universitário da Universidade de São PauloAutopsy and Case Reports v.11 20212021-01-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602021000100700en10.4322/acr.2020.186
institution SCIELO
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country Brasil
countrycode BR
component Revista
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region America del Sur
libraryname SciELO
language English
format Digital
author Figueiredo,Marília A.
Medeiros,Frederico Buhatem
Ortega,Karem López
spellingShingle Figueiredo,Marília A.
Medeiros,Frederico Buhatem
Ortega,Karem López
Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate
author_facet Figueiredo,Marília A.
Medeiros,Frederico Buhatem
Ortega,Karem López
author_sort Figueiredo,Marília A.
title Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate
title_short Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate
title_full Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate
title_fullStr Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate
title_full_unstemmed Osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate
title_sort osteonecrosis of the jaw in a patient under treatment of osteoporosis with oral bisphosphonate
description ABSTRACT Although uncommon in patients under oral therapy, bisphosphonate-related osteonecrosis of the jaw (BRONJ) can be a very severe issue. Early intervention with surgical resection should be the preferable method of treating any stage of the disease, resulting in better outcomes and decreasing the morbidity of this condition. A 77-year-old female patient attended the Special Care Dentistry Centre of the University of São Paulo Faculty of Dentistry (CAPE FOUSP) complaining mainly of “an exposed bone that appeared after tooth extraction performed six months earlier”. The patient was diagnosed with osteonecrosis associated with bisphosphonate (sodium ibandronate) and surgically treated with removal of bone sequestration and antibiotic therapy. The patient was followed up for six years (a total of 6 appointments), presenting good general health and no sign of bone exposure. Imaging findings showed no changes related to BRONJ either.
publisher Hospital Universitário da Universidade de São Paulo
publishDate 2021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602021000100700
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AT medeirosfredericobuhatem osteonecrosisofthejawinapatientundertreatmentofosteoporosiswithoralbisphosphonate
AT ortegakaremlopez osteonecrosisofthejawinapatientundertreatmentofosteoporosiswithoralbisphosphonate
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