Pseudomonas aeruginosa necrotizing bronchopneumonia

Pseudomonas aeruginosa necrotizing bronchopneumonia

ABSTRACT Extremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality, poor growth, and neurodevelopmental outcomes. Pseudomonas aeruginosa (P. aeruginosa) infection is an uncommon but potentially devastating cause of pneumonia and sepsis in the ELBW population. P. aeruginosa is an important cause of healthcare-associated infections (HAI) or nosocomial infections. P. aeruginosa can perceive unfavorable environmental changes and orchestrate adaptations by developing plasmid-mediated and adaptive resistance to antibiotics. We describe an ELBW infant born at 26 weeks’ gestation who succumbed at 13 days of life to P. aeruginosa infection. Some of the factors related to the pathogenesis and multidrug resistance are described.

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Main Author: Kylat,Ranjit I
Format: Digital revista
Language:English
Published: Hospital Universitário da Universidade de São Paulo 2021
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602021000100412
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spelling oai:scielo:S2236-196020210001004122021-05-05Pseudomonas aeruginosa necrotizing bronchopneumoniaKylat,Ranjit I Pseudomonas aeruginosa Bronchopneumonia Infant, Premature Infant, Low Birth Weight Neonatal Sepsis Cross Infection ABSTRACT Extremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality, poor growth, and neurodevelopmental outcomes. Pseudomonas aeruginosa (P. aeruginosa) infection is an uncommon but potentially devastating cause of pneumonia and sepsis in the ELBW population. P. aeruginosa is an important cause of healthcare-associated infections (HAI) or nosocomial infections. P. aeruginosa can perceive unfavorable environmental changes and orchestrate adaptations by developing plasmid-mediated and adaptive resistance to antibiotics. We describe an ELBW infant born at 26 weeks’ gestation who succumbed at 13 days of life to P. aeruginosa infection. Some of the factors related to the pathogenesis and multidrug resistance are described.info:eu-repo/semantics/openAccessHospital Universitário da Universidade de São PauloAutopsy and Case Reports v.11 20212021-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602021000100412en10.4322/acr.2021.271
institution SCIELO
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Kylat,Ranjit I
spellingShingle Kylat,Ranjit I
Pseudomonas aeruginosa necrotizing bronchopneumonia
author_facet Kylat,Ranjit I
author_sort Kylat,Ranjit I
title Pseudomonas aeruginosa necrotizing bronchopneumonia
title_short Pseudomonas aeruginosa necrotizing bronchopneumonia
title_full Pseudomonas aeruginosa necrotizing bronchopneumonia
title_fullStr Pseudomonas aeruginosa necrotizing bronchopneumonia
title_full_unstemmed Pseudomonas aeruginosa necrotizing bronchopneumonia
title_sort pseudomonas aeruginosa necrotizing bronchopneumonia
description ABSTRACT Extremely low birth weight (ELBW) infants are at particularly high risk for infection due to an immature immune system, invasive procedures such as endotracheal intubation, intravascular catheterization, and other factors. Neonatal infections in this population are associated with a high mortality, poor growth, and neurodevelopmental outcomes. Pseudomonas aeruginosa (P. aeruginosa) infection is an uncommon but potentially devastating cause of pneumonia and sepsis in the ELBW population. P. aeruginosa is an important cause of healthcare-associated infections (HAI) or nosocomial infections. P. aeruginosa can perceive unfavorable environmental changes and orchestrate adaptations by developing plasmid-mediated and adaptive resistance to antibiotics. We describe an ELBW infant born at 26 weeks’ gestation who succumbed at 13 days of life to P. aeruginosa infection. Some of the factors related to the pathogenesis and multidrug resistance are described.
publisher Hospital Universitário da Universidade de São Paulo
publishDate 2021
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S2236-19602021000100412
work_keys_str_mv AT kylatranjiti pseudomonasaeruginosanecrotizingbronchopneumonia
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