Post-COVID conditions: a Portuguese primary care study

Abstract The Centers for Disease Control and Prevention propose the term long COVID or post-COVID conditions for symptoms that develop during or after COVID-19, continue for at least two months, and are not explained by an alternative diagnosis. In this cross-sectional study, we aimed at estimating the proportion of COVID-19 patients that presented post-COVID conditions, describing their baseline characteristics and main persisting symptoms. We included 497 adult patients who had recovered from mild to moderate COVID-19, using a structured questionnaire, 12 to 16 weeks after disease onset. The cumulative incidence for post-COVID conditions was 47.5% (n=236). The most frequent symptoms were fatigue (n=151, 30.4%) and dyspnea (n=131, 26.4%). After adjusting for covariables male gender was found to be associated with lower odds of post-COVID conditions (OR=0.36, p<0.001). Body Mass Index <20 (OR=0.28, p=0.014) and [30-35[ (OR=0.42, p=0.006) seemed to have less persistent symptoms when compared to [20-25[. No other baseline demographic or clinical features were found to be significantly associated with post-COVID conditions. Our study suggests that post-COVID conditions persist in a large subset of non-severe diseases. Physicians should continue to monitor these patients to identify and treat post-acute sequelae of SARS-CoV-2 infection, particularly in what concerns primary care.

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Main Authors: Oliveira,Tiago Gomes de, Almeida,Hugo Silva, Pereira,Inês Baptista, Fernandes,Maria João, Almeida,Mariana Dias, Carvalho,Carlos, Monteiro,Ana Bessa, Belo,Ana Filipa
Format: Digital revista
Language:English
Published: Associação Portuguesa de Medicina Geral e Familiar 2023
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-51732023000400351
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spelling oai:scielo:S2182-517320230004003512023-11-08Post-COVID conditions: a Portuguese primary care studyOliveira,Tiago Gomes deAlmeida,Hugo SilvaPereira,Inês BaptistaFernandes,Maria JoãoAlmeida,Mariana DiasCarvalho,CarlosMonteiro,Ana BessaBelo,Ana Filipa COVID-19 Post-acute COVID-19 syndrome Post-COVID conditions Long COVID Abstract The Centers for Disease Control and Prevention propose the term long COVID or post-COVID conditions for symptoms that develop during or after COVID-19, continue for at least two months, and are not explained by an alternative diagnosis. In this cross-sectional study, we aimed at estimating the proportion of COVID-19 patients that presented post-COVID conditions, describing their baseline characteristics and main persisting symptoms. We included 497 adult patients who had recovered from mild to moderate COVID-19, using a structured questionnaire, 12 to 16 weeks after disease onset. The cumulative incidence for post-COVID conditions was 47.5% (n=236). The most frequent symptoms were fatigue (n=151, 30.4%) and dyspnea (n=131, 26.4%). After adjusting for covariables male gender was found to be associated with lower odds of post-COVID conditions (OR=0.36, p<0.001). Body Mass Index <20 (OR=0.28, p=0.014) and [30-35[ (OR=0.42, p=0.006) seemed to have less persistent symptoms when compared to [20-25[. No other baseline demographic or clinical features were found to be significantly associated with post-COVID conditions. Our study suggests that post-COVID conditions persist in a large subset of non-severe diseases. Physicians should continue to monitor these patients to identify and treat post-acute sequelae of SARS-CoV-2 infection, particularly in what concerns primary care.info:eu-repo/semantics/openAccessAssociação Portuguesa de Medicina Geral e FamiliarRevista Portuguesa de Medicina Geral e Familiar v.39 n.4 20232023-07-01info:eu-repo/semantics/articletext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-51732023000400351en10.32385/rpmgf.v39i4.13443
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country Portugal
countrycode PT
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region Europa del Sur
libraryname SciELO
language English
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author Oliveira,Tiago Gomes de
Almeida,Hugo Silva
Pereira,Inês Baptista
Fernandes,Maria João
Almeida,Mariana Dias
Carvalho,Carlos
Monteiro,Ana Bessa
Belo,Ana Filipa
spellingShingle Oliveira,Tiago Gomes de
Almeida,Hugo Silva
Pereira,Inês Baptista
Fernandes,Maria João
Almeida,Mariana Dias
Carvalho,Carlos
Monteiro,Ana Bessa
Belo,Ana Filipa
Post-COVID conditions: a Portuguese primary care study
author_facet Oliveira,Tiago Gomes de
Almeida,Hugo Silva
Pereira,Inês Baptista
Fernandes,Maria João
Almeida,Mariana Dias
Carvalho,Carlos
Monteiro,Ana Bessa
Belo,Ana Filipa
author_sort Oliveira,Tiago Gomes de
title Post-COVID conditions: a Portuguese primary care study
title_short Post-COVID conditions: a Portuguese primary care study
title_full Post-COVID conditions: a Portuguese primary care study
title_fullStr Post-COVID conditions: a Portuguese primary care study
title_full_unstemmed Post-COVID conditions: a Portuguese primary care study
title_sort post-covid conditions: a portuguese primary care study
description Abstract The Centers for Disease Control and Prevention propose the term long COVID or post-COVID conditions for symptoms that develop during or after COVID-19, continue for at least two months, and are not explained by an alternative diagnosis. In this cross-sectional study, we aimed at estimating the proportion of COVID-19 patients that presented post-COVID conditions, describing their baseline characteristics and main persisting symptoms. We included 497 adult patients who had recovered from mild to moderate COVID-19, using a structured questionnaire, 12 to 16 weeks after disease onset. The cumulative incidence for post-COVID conditions was 47.5% (n=236). The most frequent symptoms were fatigue (n=151, 30.4%) and dyspnea (n=131, 26.4%). After adjusting for covariables male gender was found to be associated with lower odds of post-COVID conditions (OR=0.36, p<0.001). Body Mass Index <20 (OR=0.28, p=0.014) and [30-35[ (OR=0.42, p=0.006) seemed to have less persistent symptoms when compared to [20-25[. No other baseline demographic or clinical features were found to be significantly associated with post-COVID conditions. Our study suggests that post-COVID conditions persist in a large subset of non-severe diseases. Physicians should continue to monitor these patients to identify and treat post-acute sequelae of SARS-CoV-2 infection, particularly in what concerns primary care.
publisher Associação Portuguesa de Medicina Geral e Familiar
publishDate 2023
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-51732023000400351
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