Syphilitic Balanitis of Follmann: Laboratory Pitfalls

Syphilitic Balanitis of Follmann: Laboratory Pitfalls

ABSTRACT We report a case of early syphilis, presenting as balanitis and papular syphilides in an HIV-infected patient, with a previous history of syphilis infection, which demonstrated a false negative VDRL testing due to a prozone phenomenon. This false negative response results from overwhelming antibody titers, which interfere with the proper formation of the antigen-antibody lattice network, necessary to visualize a positive flocculation test.

Saved in:
Bibliographic Details
Main Authors: Almeida,Filipa Tavares, Azevedo,Filomena, Lisboa,Carmen
Format: Digital revista
Language:English
Published: Sociedade Portuguesa de Dermatologia e Venereologia 2020
Online Access:http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300062
Tags: Add Tag
No Tags, Be the first to tag this record!
id oai:scielo:S2182-23952020000300062
record_format ojs
spelling oai:scielo:S2182-239520200003000622022-02-24Syphilitic Balanitis of Follmann: Laboratory PitfallsAlmeida,Filipa TavaresAzevedo,FilomenaLisboa,Carmen Keywords: Balanitis/diagnosis Syphilis/diagnosis. ABSTRACT We report a case of early syphilis, presenting as balanitis and papular syphilides in an HIV-infected patient, with a previous history of syphilis infection, which demonstrated a false negative VDRL testing due to a prozone phenomenon. This false negative response results from overwhelming antibody titers, which interfere with the proper formation of the antigen-antibody lattice network, necessary to visualize a positive flocculation test.info:eu-repo/semantics/openAccessSociedade Portuguesa de Dermatologia e VenereologiaRevista da Sociedade Portuguesa de Dermatologia e Venereologia v.78 n.3 20202020-09-01info:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300062en10.29021/spdv.78.3.1199
institution SCIELO
collection OJS
country Portugal
countrycode PT
component Revista
access En linea
databasecode rev-scielo-pt
tag revista
region Europa del Sur
libraryname SciELO
language English
format Digital
author Almeida,Filipa Tavares
Azevedo,Filomena
Lisboa,Carmen
spellingShingle Almeida,Filipa Tavares
Azevedo,Filomena
Lisboa,Carmen
Syphilitic Balanitis of Follmann: Laboratory Pitfalls
author_facet Almeida,Filipa Tavares
Azevedo,Filomena
Lisboa,Carmen
author_sort Almeida,Filipa Tavares
title Syphilitic Balanitis of Follmann: Laboratory Pitfalls
title_short Syphilitic Balanitis of Follmann: Laboratory Pitfalls
title_full Syphilitic Balanitis of Follmann: Laboratory Pitfalls
title_fullStr Syphilitic Balanitis of Follmann: Laboratory Pitfalls
title_full_unstemmed Syphilitic Balanitis of Follmann: Laboratory Pitfalls
title_sort syphilitic balanitis of follmann: laboratory pitfalls
description ABSTRACT We report a case of early syphilis, presenting as balanitis and papular syphilides in an HIV-infected patient, with a previous history of syphilis infection, which demonstrated a false negative VDRL testing due to a prozone phenomenon. This false negative response results from overwhelming antibody titers, which interfere with the proper formation of the antigen-antibody lattice network, necessary to visualize a positive flocculation test.
publisher Sociedade Portuguesa de Dermatologia e Venereologia
publishDate 2020
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2182-23952020000300062
work_keys_str_mv AT almeidafilipatavares syphiliticbalanitisoffollmannlaboratorypitfalls
AT azevedofilomena syphiliticbalanitisoffollmannlaboratorypitfalls
AT lisboacarmen syphiliticbalanitisoffollmannlaboratorypitfalls
_version_ 1756003680550649856

Similar Items