Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil

ABSTRACT The essential oil composition of the Ocotea bicolor, native plant of Brazil, was studied for the first time. The essential oil of the leaf was obtained by hydrodistillation and analyzed by GC/MS. The analytical procedure revealed a predominance of sesquiterpenes, δ-cadinene (7.39%), β-sesquiphellandrene (6.67%), β-elemene (5.41%) and α-cadinol (5,23%). The essential oil was submitted to brine shrimp toxicity evaluation, antioxidant and antibacterial tests. The antioxidant activity by the formation of phosphomolybdenum complex method presented positive results. The minimum inhibitory concentration (MIC) values were higher than 1000 μg/mL for the microorganisms tested. Toxicity activity revealed LC50 results of 40.10 (μg/mL), being toxic to the organisms in this study.

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Main Authors: Damasceno,Carolina Sette Barbosa, Oliveira,Letícia Freire de, Szabo,Ellis Marina, Souza,Ângela Maria, Dias,Josiane Fatima Gaspari, Miguel,Marilis Dalarmi, Miguel,Obdúlio Gomes
Format: Digital revista
Language:English
Published: Universidade de São Paulo, Faculdade de Ciências Farmacêuticas 2017
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400615
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spelling oai:scielo:S1984-825020170004006152018-03-02Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oilDamasceno,Carolina Sette BarbosaOliveira,Letícia Freire deSzabo,Ellis MarinaSouza,Ângela MariaDias,Josiane Fatima GaspariMiguel,Marilis DalarmiMiguel,Obdúlio Gomes Ocotea bicolor/Oil essential/chemical composition Lauraceae Antioxidant activity Biological activity ABSTRACT The essential oil composition of the Ocotea bicolor, native plant of Brazil, was studied for the first time. The essential oil of the leaf was obtained by hydrodistillation and analyzed by GC/MS. The analytical procedure revealed a predominance of sesquiterpenes, δ-cadinene (7.39%), β-sesquiphellandrene (6.67%), β-elemene (5.41%) and α-cadinol (5,23%). The essential oil was submitted to brine shrimp toxicity evaluation, antioxidant and antibacterial tests. The antioxidant activity by the formation of phosphomolybdenum complex method presented positive results. The minimum inhibitory concentration (MIC) values were higher than 1000 μg/mL for the microorganisms tested. Toxicity activity revealed LC50 results of 40.10 (μg/mL), being toxic to the organisms in this study.info:eu-repo/semantics/openAccessUniversidade de São Paulo, Faculdade de Ciências FarmacêuticasBrazilian Journal of Pharmaceutical Sciences v.53 n.4 20172017-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400615en10.1590/s2175-97902017000417298
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country Brasil
countrycode BR
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region America del Sur
libraryname SciELO
language English
format Digital
author Damasceno,Carolina Sette Barbosa
Oliveira,Letícia Freire de
Szabo,Ellis Marina
Souza,Ângela Maria
Dias,Josiane Fatima Gaspari
Miguel,Marilis Dalarmi
Miguel,Obdúlio Gomes
spellingShingle Damasceno,Carolina Sette Barbosa
Oliveira,Letícia Freire de
Szabo,Ellis Marina
Souza,Ângela Maria
Dias,Josiane Fatima Gaspari
Miguel,Marilis Dalarmi
Miguel,Obdúlio Gomes
Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil
author_facet Damasceno,Carolina Sette Barbosa
Oliveira,Letícia Freire de
Szabo,Ellis Marina
Souza,Ângela Maria
Dias,Josiane Fatima Gaspari
Miguel,Marilis Dalarmi
Miguel,Obdúlio Gomes
author_sort Damasceno,Carolina Sette Barbosa
title Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil
title_short Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil
title_full Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil
title_fullStr Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil
title_full_unstemmed Chemical composition, antioxidant and biological activity of Ocotea bicolor Vattimo-Gil (LAURACEAE) essential oil
title_sort chemical composition, antioxidant and biological activity of ocotea bicolor vattimo-gil (lauraceae) essential oil
description ABSTRACT The essential oil composition of the Ocotea bicolor, native plant of Brazil, was studied for the first time. The essential oil of the leaf was obtained by hydrodistillation and analyzed by GC/MS. The analytical procedure revealed a predominance of sesquiterpenes, δ-cadinene (7.39%), β-sesquiphellandrene (6.67%), β-elemene (5.41%) and α-cadinol (5,23%). The essential oil was submitted to brine shrimp toxicity evaluation, antioxidant and antibacterial tests. The antioxidant activity by the formation of phosphomolybdenum complex method presented positive results. The minimum inhibitory concentration (MIC) values were higher than 1000 μg/mL for the microorganisms tested. Toxicity activity revealed LC50 results of 40.10 (μg/mL), being toxic to the organisms in this study.
publisher Universidade de São Paulo, Faculdade de Ciências Farmacêuticas
publishDate 2017
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000400615
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