Effect of Xylitol Varnishes on the Inhibition of Demineralization in Vitro
Abstract Objective: To evaluate the efficacy of xylitol varnishes in the inhibition of enamel demineralization in vitro. Material and Methods: Bovine enamel blocks (n=120) were randomly allocated to four groups (n = 30), and the surface hardness (SH) was measured at baseline. The blocks were treated with the following varnishes: 20% xylitol, 20% xylitol plus F (5% NaF), Duraphat™ (5% NaF, positive control), and placebo (no-F/xylitol, negative control). The varnishes were applied and removed after 6 h of immersion in artificial saliva. The blocks were subjected to pH cycles (demineralization and remineralization for 2 and 22h/day, respectively, for 8 days). Surface and cross-sectional hardnesses were measured to calculate the percentage of SH loss (%SHL) and the integrated loss of the subsurface hardness (ΔKHN). Data were statistically analyzed using Kruskal-Wallis and Tukey’s tests (p<0.05). Results: %SHL was significantly decreased by 20% xylitol plus F, Duraphat™, and 20% xylitol varnishes compared to placebo. The use of 20% xylitol plus F varnish led to a significantly lower percentage of SH loss compared to the use of 20% xylitol varnish without F. However, the experimental and commercial varnishes led to significantly lower subsurface demineralization compared to placebo and did not differ from each other. Conclusion: Xylitol varnishes, especially when combined with F, effectively prevent enamel demineralization.
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Associação de Apoio à Pesquisa em Saúde Bucal
2022
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oai:scielo:S1983-463220220001003542022-12-02Effect of Xylitol Varnishes on the Inhibition of Demineralization in VitroNaves,Paula AnderyMoura,Alexandre Lima deRodrigues,Marcela CharantolaDiniz,Michele BaffiArana-Chavez,Victor ElliasJordão,Maísa CamilloCardoso,Cristiane de Almeida Baldini Dental Caries Tooth Demineralization Xylitol Abstract Objective: To evaluate the efficacy of xylitol varnishes in the inhibition of enamel demineralization in vitro. Material and Methods: Bovine enamel blocks (n=120) were randomly allocated to four groups (n = 30), and the surface hardness (SH) was measured at baseline. The blocks were treated with the following varnishes: 20% xylitol, 20% xylitol plus F (5% NaF), Duraphat™ (5% NaF, positive control), and placebo (no-F/xylitol, negative control). The varnishes were applied and removed after 6 h of immersion in artificial saliva. The blocks were subjected to pH cycles (demineralization and remineralization for 2 and 22h/day, respectively, for 8 days). Surface and cross-sectional hardnesses were measured to calculate the percentage of SH loss (%SHL) and the integrated loss of the subsurface hardness (ΔKHN). Data were statistically analyzed using Kruskal-Wallis and Tukey’s tests (p<0.05). Results: %SHL was significantly decreased by 20% xylitol plus F, Duraphat™, and 20% xylitol varnishes compared to placebo. The use of 20% xylitol plus F varnish led to a significantly lower percentage of SH loss compared to the use of 20% xylitol varnish without F. However, the experimental and commercial varnishes led to significantly lower subsurface demineralization compared to placebo and did not differ from each other. Conclusion: Xylitol varnishes, especially when combined with F, effectively prevent enamel demineralization.info:eu-repo/semantics/openAccessAssociação de Apoio à Pesquisa em Saúde BucalPesquisa Brasileira em Odontopediatria e Clínica Integrada v.22 20222022-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-46322022000100354en10.1590/pboci.2022.048 |
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Naves,Paula Andery Moura,Alexandre Lima de Rodrigues,Marcela Charantola Diniz,Michele Baffi Arana-Chavez,Victor Ellias Jordão,Maísa Camillo Cardoso,Cristiane de Almeida Baldini |
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Naves,Paula Andery Moura,Alexandre Lima de Rodrigues,Marcela Charantola Diniz,Michele Baffi Arana-Chavez,Victor Ellias Jordão,Maísa Camillo Cardoso,Cristiane de Almeida Baldini Effect of Xylitol Varnishes on the Inhibition of Demineralization in Vitro |
author_facet |
Naves,Paula Andery Moura,Alexandre Lima de Rodrigues,Marcela Charantola Diniz,Michele Baffi Arana-Chavez,Victor Ellias Jordão,Maísa Camillo Cardoso,Cristiane de Almeida Baldini |
author_sort |
Naves,Paula Andery |
title |
Effect of Xylitol Varnishes on the Inhibition of Demineralization in Vitro |
title_short |
Effect of Xylitol Varnishes on the Inhibition of Demineralization in Vitro |
title_full |
Effect of Xylitol Varnishes on the Inhibition of Demineralization in Vitro |
title_fullStr |
Effect of Xylitol Varnishes on the Inhibition of Demineralization in Vitro |
title_full_unstemmed |
Effect of Xylitol Varnishes on the Inhibition of Demineralization in Vitro |
title_sort |
effect of xylitol varnishes on the inhibition of demineralization in vitro |
description |
Abstract Objective: To evaluate the efficacy of xylitol varnishes in the inhibition of enamel demineralization in vitro. Material and Methods: Bovine enamel blocks (n=120) were randomly allocated to four groups (n = 30), and the surface hardness (SH) was measured at baseline. The blocks were treated with the following varnishes: 20% xylitol, 20% xylitol plus F (5% NaF), Duraphat™ (5% NaF, positive control), and placebo (no-F/xylitol, negative control). The varnishes were applied and removed after 6 h of immersion in artificial saliva. The blocks were subjected to pH cycles (demineralization and remineralization for 2 and 22h/day, respectively, for 8 days). Surface and cross-sectional hardnesses were measured to calculate the percentage of SH loss (%SHL) and the integrated loss of the subsurface hardness (ΔKHN). Data were statistically analyzed using Kruskal-Wallis and Tukey’s tests (p<0.05). Results: %SHL was significantly decreased by 20% xylitol plus F, Duraphat™, and 20% xylitol varnishes compared to placebo. The use of 20% xylitol plus F varnish led to a significantly lower percentage of SH loss compared to the use of 20% xylitol varnish without F. However, the experimental and commercial varnishes led to significantly lower subsurface demineralization compared to placebo and did not differ from each other. Conclusion: Xylitol varnishes, especially when combined with F, effectively prevent enamel demineralization. |
publisher |
Associação de Apoio à Pesquisa em Saúde Bucal |
publishDate |
2022 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-46322022000100354 |
work_keys_str_mv |
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