Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression
Abstract Objective: To determine the correlation between levels of methyl mercaptan (CH3SH) hydrogen sulfide (H2S), the proportion of Prevotella intermedia (Pi), and matrix metalloproteinase-8 (MMP-8) gene expression levels in periodontitis patients accompanied by halitosis. Material and Methods: Samples were obtained from gingival crevicular fluid (GCF) in the deepest pocket and by swabbing in the tongue coating area in patients with periodontitis presenting with halitosis (n = 23) and healthy subjects as controls (n = 7). The values of CH3SH and H2S were obtained using Oral Chroma. The proportion of Pi and MMP-8 expression levels were evaluated using PCR-RT. All the result was statistically analyzed using SPSS software. Results: The levels of CH3SH and H2S in participants with PD ≥ 6 mm showed a robust negative correlation with the proportion of P. intermedia in GCF and tongue coating. No statistically significant association was detected between CH3SH and H2S levels and MMP-8 expression levels (p>0.05). Conclusion: There is no association between CH3SH and H2S levels, the proportion of P. intermedia, and MMP-8 expression in patients with periodontitis accompanied by halitosis.
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Associação de Apoio à Pesquisa em Saúde Bucal
2022
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oai:scielo:S1983-463220220001003372022-12-02Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 ExpressionMaitimu,Fergy ChristinSoeroso,YuniartiSunarto,HariBachtiar,Boy Muchlis Halitosis Periodontitis Prevotella intermedia Matrix Metalloproteinase-8 Abstract Objective: To determine the correlation between levels of methyl mercaptan (CH3SH) hydrogen sulfide (H2S), the proportion of Prevotella intermedia (Pi), and matrix metalloproteinase-8 (MMP-8) gene expression levels in periodontitis patients accompanied by halitosis. Material and Methods: Samples were obtained from gingival crevicular fluid (GCF) in the deepest pocket and by swabbing in the tongue coating area in patients with periodontitis presenting with halitosis (n = 23) and healthy subjects as controls (n = 7). The values of CH3SH and H2S were obtained using Oral Chroma. The proportion of Pi and MMP-8 expression levels were evaluated using PCR-RT. All the result was statistically analyzed using SPSS software. Results: The levels of CH3SH and H2S in participants with PD ≥ 6 mm showed a robust negative correlation with the proportion of P. intermedia in GCF and tongue coating. No statistically significant association was detected between CH3SH and H2S levels and MMP-8 expression levels (p>0.05). Conclusion: There is no association between CH3SH and H2S levels, the proportion of P. intermedia, and MMP-8 expression in patients with periodontitis accompanied by halitosis.info:eu-repo/semantics/openAccessAssociação de Apoio à Pesquisa em Saúde BucalPesquisa Brasileira em Odontopediatria e Clínica Integrada v.22 20222022-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-46322022000100337en10.1590/pboci.2022.049 |
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Maitimu,Fergy Christin Soeroso,Yuniarti Sunarto,Hari Bachtiar,Boy Muchlis |
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Maitimu,Fergy Christin Soeroso,Yuniarti Sunarto,Hari Bachtiar,Boy Muchlis Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression |
author_facet |
Maitimu,Fergy Christin Soeroso,Yuniarti Sunarto,Hari Bachtiar,Boy Muchlis |
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Maitimu,Fergy Christin |
title |
Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression |
title_short |
Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression |
title_full |
Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression |
title_fullStr |
Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression |
title_full_unstemmed |
Association between Volatile Sulfur Compounds Prevotella intermedia and Matrix Metalloproteinase-8 Expression |
title_sort |
association between volatile sulfur compounds prevotella intermedia and matrix metalloproteinase-8 expression |
description |
Abstract Objective: To determine the correlation between levels of methyl mercaptan (CH3SH) hydrogen sulfide (H2S), the proportion of Prevotella intermedia (Pi), and matrix metalloproteinase-8 (MMP-8) gene expression levels in periodontitis patients accompanied by halitosis. Material and Methods: Samples were obtained from gingival crevicular fluid (GCF) in the deepest pocket and by swabbing in the tongue coating area in patients with periodontitis presenting with halitosis (n = 23) and healthy subjects as controls (n = 7). The values of CH3SH and H2S were obtained using Oral Chroma. The proportion of Pi and MMP-8 expression levels were evaluated using PCR-RT. All the result was statistically analyzed using SPSS software. Results: The levels of CH3SH and H2S in participants with PD ≥ 6 mm showed a robust negative correlation with the proportion of P. intermedia in GCF and tongue coating. No statistically significant association was detected between CH3SH and H2S levels and MMP-8 expression levels (p>0.05). Conclusion: There is no association between CH3SH and H2S levels, the proportion of P. intermedia, and MMP-8 expression in patients with periodontitis accompanied by halitosis. |
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Associação de Apoio à Pesquisa em Saúde Bucal |
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2022 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1983-46322022000100337 |
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AT maitimufergychristin associationbetweenvolatilesulfurcompoundsprevotellaintermediaandmatrixmetalloproteinase8expression AT soerosoyuniarti associationbetweenvolatilesulfurcompoundsprevotellaintermediaandmatrixmetalloproteinase8expression AT sunartohari associationbetweenvolatilesulfurcompoundsprevotellaintermediaandmatrixmetalloproteinase8expression AT bachtiarboymuchlis associationbetweenvolatilesulfurcompoundsprevotellaintermediaandmatrixmetalloproteinase8expression |
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1756472096568901633 |