Acute melatonin administration enhances aerobic tolerance: an analysis of biochemical and hematological parameters
Abstract Aims This study is aimed at testing the acute melatonin administration (oral; 6 mg) on aerobic tolerance at cycloergometer and analyzing the consequences on biochemical and hematological parameters. Methods The maximal aerobic capacity intensity (iMAC) at cycloergometer of eleven male healthy men (24.18±3.92 years-old; 87.07±12.48 kg; 1.82±0.05 m; 26.18±3.63 kg/m2; and 16.28±5.77 % of fat) was individually determined and used to perform a time to exhaustion (tlim) trial of 30 minutes after melatonin or placebo administration. We observed 48-72h interval between tests, performed in a double-blind experiment design. In order to determine hematological and biochemical parameters we collected venous blood samples before and after tlim. Statistical significance was set at 5%. Results The intensity and the lactatemia corresponding to the maximal aerobic capacity were 120.88±18.78 W and 3.32±1.03 mmol.L-1, respectively. The tlim with placebo (33.94±15.26 min, confidence interval = 24.92 - 42.95) was significantly lower than the tlim with melatonin (41.94±17.22 min; CI = 31.76 - 52.12; p = 0.03; 19.06%; effect size = 0.49). All of the 21 analyzed blood physiological variables resulted in no significant variation after tlim when placebo was compared to melatonin, except for total sera cholesterol (lower after exercise with melatonin). Conclusion Acute melatonin administration enhanced aerobic tolerance at iMAC in 19% at cycloergometer; however, the biochemical and hematological variables assessed were not significantly modulated.
Main Authors: | Beck,Wladimir Rafael, Messias,Leonardo Henrique Dalcheco, Silva,Franciele Carneiro da, Manchado-Gobatto,Fúlvia Barros, Gobatto,Claudio Alexandre |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Universidade Estadual Paulista
2018
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-65742018000200305 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Adaptação de protocolos invasivos e não invasivos para avaliações aeróbias e anaeróbias específicas ao basquetebol feminino
by: Camargo,Bruno Ferreira, et al.
Published: (2013) -
Metabolic profile and spontaneous physical activity modulation under short-term food restriction in young rats.
by: Beck,Wladimir Rafael, et al.
Published: (2017) -
Two water environment adaptation models enhance motor behavior and improve the success of the lactate minimum test in swimming rats
by: Lima,Adriano Alves de, et al.
Published: (2017) -
Hematological, biochemical, and endocrine parameters in acute response to increasing-intensity exercise in Colombian Paso horses
by: Zuluaga Cabrera,Angélica María, et al.
Published: (2022) -
Exercício contínuo e intermitente: Efeitos do treinamento e do destreinamento sobre o peso corporal e o metabolismo muscular de ratos obesos
by: Braga,Larissa, et al.
Published: (2006)