Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study
ABSTRACT. Additional clinical tools should be investigated to facilitate and aid the early diagnosis of cognitive decline. Postural control worsens with aging and this may be related to pathological cognitive impairment. Objective: to compare the balance of older adults without dementia in a control group (CG) and with Alzheimer’s disease (AD), to observe the possible association with the independent variables (diagnosis, age, gender, and global cognition) and to verify the best posturographic analyses to determine the difference between the groups. Methods: 86 older adults (AD = 48; CG = 38) were evaluated using the Berg Balance Scale (BBS) and postural control was assessed by stabilometry on the Wii Balance Board ® (WBB). Independent T, Mann-Whitney U-tests, Effect Size (ES) and a linear regression were performed. Results: there was a significant difference for Elliptical Area, Total Velocity, Medio-Lateral displacements with closed eyes and open eyes, antero-posterior, with closed eyes and BBS between groups. These variables showed a large effect size for BBS (-1.02), Elliptical Area (0.83) with closed eyes, Medio-Lateral (0.80, 0.96) and Total Velocity (0.92; 1.10) with eyes open and eyes closed, respectively. Regression indicated global cognition accompanied by age, gender, and diagnosis influenced postural control. Conclusion: patients with AD showed impaired postural control compared to Control Group subjects. Total Velocity with closed eyes was the most sensitive parameter for differentiating groups and should be better investigated as a possible motor biomarker of dementia in posturographic analysis with WBB.
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Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
2019
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oai:scielo:S1980-576420190002001962019-09-20Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional studySant’Anna,PaulaSilva,Felipe de OliveiraRodrigues,Ana Carolina de Mello AlvesPlácido,JéssicaFerreira,José ViniciusMeereis,Estele Caroline WelterPraxedes,JomiltoMarinho,ValeskaLaks,JersonSobral Monteiro-Junior,RenatoDeslandes,Andrea Camaz motor biomarker Alzheimer’s disease postural control balance dementia older adults ABSTRACT. Additional clinical tools should be investigated to facilitate and aid the early diagnosis of cognitive decline. Postural control worsens with aging and this may be related to pathological cognitive impairment. Objective: to compare the balance of older adults without dementia in a control group (CG) and with Alzheimer’s disease (AD), to observe the possible association with the independent variables (diagnosis, age, gender, and global cognition) and to verify the best posturographic analyses to determine the difference between the groups. Methods: 86 older adults (AD = 48; CG = 38) were evaluated using the Berg Balance Scale (BBS) and postural control was assessed by stabilometry on the Wii Balance Board ® (WBB). Independent T, Mann-Whitney U-tests, Effect Size (ES) and a linear regression were performed. Results: there was a significant difference for Elliptical Area, Total Velocity, Medio-Lateral displacements with closed eyes and open eyes, antero-posterior, with closed eyes and BBS between groups. These variables showed a large effect size for BBS (-1.02), Elliptical Area (0.83) with closed eyes, Medio-Lateral (0.80, 0.96) and Total Velocity (0.92; 1.10) with eyes open and eyes closed, respectively. Regression indicated global cognition accompanied by age, gender, and diagnosis influenced postural control. Conclusion: patients with AD showed impaired postural control compared to Control Group subjects. Total Velocity with closed eyes was the most sensitive parameter for differentiating groups and should be better investigated as a possible motor biomarker of dementia in posturographic analysis with WBB.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e EnvelhecimentoDementia & Neuropsychologia v.13 n.2 20192019-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000200196en10.1590/1980-57642018dn13-020008 |
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Sant’Anna,Paula Silva,Felipe de Oliveira Rodrigues,Ana Carolina de Mello Alves Plácido,Jéssica Ferreira,José Vinicius Meereis,Estele Caroline Welter Praxedes,Jomilto Marinho,Valeska Laks,Jerson Sobral Monteiro-Junior,Renato Deslandes,Andrea Camaz |
spellingShingle |
Sant’Anna,Paula Silva,Felipe de Oliveira Rodrigues,Ana Carolina de Mello Alves Plácido,Jéssica Ferreira,José Vinicius Meereis,Estele Caroline Welter Praxedes,Jomilto Marinho,Valeska Laks,Jerson Sobral Monteiro-Junior,Renato Deslandes,Andrea Camaz Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
author_facet |
Sant’Anna,Paula Silva,Felipe de Oliveira Rodrigues,Ana Carolina de Mello Alves Plácido,Jéssica Ferreira,José Vinicius Meereis,Estele Caroline Welter Praxedes,Jomilto Marinho,Valeska Laks,Jerson Sobral Monteiro-Junior,Renato Deslandes,Andrea Camaz |
author_sort |
Sant’Anna,Paula |
title |
Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
title_short |
Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
title_full |
Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
title_fullStr |
Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
title_full_unstemmed |
Posturographic analysis of older adults without dementia and patients with Alzheimer’s disease: A cross-sectional study |
title_sort |
posturographic analysis of older adults without dementia and patients with alzheimer’s disease: a cross-sectional study |
description |
ABSTRACT. Additional clinical tools should be investigated to facilitate and aid the early diagnosis of cognitive decline. Postural control worsens with aging and this may be related to pathological cognitive impairment. Objective: to compare the balance of older adults without dementia in a control group (CG) and with Alzheimer’s disease (AD), to observe the possible association with the independent variables (diagnosis, age, gender, and global cognition) and to verify the best posturographic analyses to determine the difference between the groups. Methods: 86 older adults (AD = 48; CG = 38) were evaluated using the Berg Balance Scale (BBS) and postural control was assessed by stabilometry on the Wii Balance Board ® (WBB). Independent T, Mann-Whitney U-tests, Effect Size (ES) and a linear regression were performed. Results: there was a significant difference for Elliptical Area, Total Velocity, Medio-Lateral displacements with closed eyes and open eyes, antero-posterior, with closed eyes and BBS between groups. These variables showed a large effect size for BBS (-1.02), Elliptical Area (0.83) with closed eyes, Medio-Lateral (0.80, 0.96) and Total Velocity (0.92; 1.10) with eyes open and eyes closed, respectively. Regression indicated global cognition accompanied by age, gender, and diagnosis influenced postural control. Conclusion: patients with AD showed impaired postural control compared to Control Group subjects. Total Velocity with closed eyes was the most sensitive parameter for differentiating groups and should be better investigated as a possible motor biomarker of dementia in posturographic analysis with WBB. |
publisher |
Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento |
publishDate |
2019 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642019000200196 |
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