Bipolar disorder, a precursor of Parkinson's disease?

Bipolar disorder, a precursor of Parkinson's disease?

ABSTRACT Parkinson's disease is a neurodegenerative disorder predominantly resulting from dopamine depletion in the substantia nigra pars compacta. Some psychiatric disorders may have dopaminergic dysfunction as their substrate. We describe a well-documented case of Parkinson's disease associated with Bipolar Disorder. Although there is some knowledge about the association between these diseases, little is known about its pathophysiology and correlation. We believe that among various hypotheses, many neurotransmitters are linked to this pathophysiology.

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Main Authors: Novaretti,Tânia M.S., Novaretti,Nathália, Tumas,Vitor
Format: Digital revista
Language:English
Published: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642016000400361
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spelling oai:scielo:S1980-576420160004003612016-12-19Bipolar disorder, a precursor of Parkinson's disease?Novaretti,Tânia M.S.Novaretti,NatháliaTumas,Vitor Parkinson's disease bipolar disorder serotoninergic pathway dopamine ABSTRACT Parkinson's disease is a neurodegenerative disorder predominantly resulting from dopamine depletion in the substantia nigra pars compacta. Some psychiatric disorders may have dopaminergic dysfunction as their substrate. We describe a well-documented case of Parkinson's disease associated with Bipolar Disorder. Although there is some knowledge about the association between these diseases, little is known about its pathophysiology and correlation. We believe that among various hypotheses, many neurotransmitters are linked to this pathophysiology.info:eu-repo/semantics/openAccessAcademia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e EnvelhecimentoDementia & Neuropsychologia v.10 n.4 20162016-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642016000400361en10.1590/s1980-5764-2016dn1004018
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region America del Sur
libraryname SciELO
language English
format Digital
author Novaretti,Tânia M.S.
Novaretti,Nathália
Tumas,Vitor
spellingShingle Novaretti,Tânia M.S.
Novaretti,Nathália
Tumas,Vitor
Bipolar disorder, a precursor of Parkinson's disease?
author_facet Novaretti,Tânia M.S.
Novaretti,Nathália
Tumas,Vitor
author_sort Novaretti,Tânia M.S.
title Bipolar disorder, a precursor of Parkinson's disease?
title_short Bipolar disorder, a precursor of Parkinson's disease?
title_full Bipolar disorder, a precursor of Parkinson's disease?
title_fullStr Bipolar disorder, a precursor of Parkinson's disease?
title_full_unstemmed Bipolar disorder, a precursor of Parkinson's disease?
title_sort bipolar disorder, a precursor of parkinson's disease?
description ABSTRACT Parkinson's disease is a neurodegenerative disorder predominantly resulting from dopamine depletion in the substantia nigra pars compacta. Some psychiatric disorders may have dopaminergic dysfunction as their substrate. We describe a well-documented case of Parkinson's disease associated with Bipolar Disorder. Although there is some knowledge about the association between these diseases, little is known about its pathophysiology and correlation. We believe that among various hypotheses, many neurotransmitters are linked to this pathophysiology.
publisher Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento
publishDate 2016
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642016000400361
work_keys_str_mv AT novarettitaniams bipolardisorderaprecursorofparkinsonsdisease
AT novarettinathalia bipolardisorderaprecursorofparkinsonsdisease
AT tumasvitor bipolardisorderaprecursorofparkinsonsdisease
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