THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)

Abstract Thrombocytosis refers to the increase in number of platelets per microliter (µL) of blood. Platelet counts greater than 1,000,000/µL may be associated with clinical signs of bleeding or thrombosis. Previous studies on underlying causes of thrombocytosis have aroused the interest of researchers about its clinical importance in dogs. The objective of this study was to analyze the blood cell counts in dogs in order to define the main diseases or clinical conditions that were associated with thrombocytosis, from 2016 to 2017. This was done to determine the incidence of thrombocytosis, and categorize the increase in platelet count with respect to severity. Of the 12,676 blood samples analyzed, 4.5% presented thrombocytosis (n = 573). Similar mean platelet counts were observed in all diagnosis or different categories of clinical conditions (neoplasms; gastrointestinal, endocrine, and ophthalmological diseases; trauma and surgery; dermatological, cardiac, neurological, infectious, respiratory, genitourinary, idiopathic, and multiple diseases; and pregnancy) with no significant difference (P ≥ 0.05). The disorders most commonly associated with thrombocytosis were gastrointestinal diseases, followed by neoplasms. Furthermore, increased platelet counts were observed in dogs treated with glucocorticoids and vincristine drugs. As for the degree of severity, extreme thrombocytosis occurred more frequently in the presence of gastrointestinal diseases.

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Main Authors: Rocha,Marcela Natacha Aparecida, Rocha,Mayara Carvalho de Sousa, Kavasaki,Mayara Lima, Rodrigues,Juliana Yuki, Souza,Weyber Ferreira de, Mendonça,Adriane Jorge
Format: Digital revista
Language:English
Published: Universidade Federal de Goiás 2019
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-68912019000100313
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spelling oai:scielo:S1809-689120190001003132019-07-16THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)Rocha,Marcela Natacha AparecidaRocha,Mayara Carvalho de SousaKavasaki,Mayara LimaRodrigues,Juliana YukiSouza,Weyber Ferreira deMendonça,Adriane Jorge gastrointestinal disease neoplasm platelets thrombosis Abstract Thrombocytosis refers to the increase in number of platelets per microliter (µL) of blood. Platelet counts greater than 1,000,000/µL may be associated with clinical signs of bleeding or thrombosis. Previous studies on underlying causes of thrombocytosis have aroused the interest of researchers about its clinical importance in dogs. The objective of this study was to analyze the blood cell counts in dogs in order to define the main diseases or clinical conditions that were associated with thrombocytosis, from 2016 to 2017. This was done to determine the incidence of thrombocytosis, and categorize the increase in platelet count with respect to severity. Of the 12,676 blood samples analyzed, 4.5% presented thrombocytosis (n = 573). Similar mean platelet counts were observed in all diagnosis or different categories of clinical conditions (neoplasms; gastrointestinal, endocrine, and ophthalmological diseases; trauma and surgery; dermatological, cardiac, neurological, infectious, respiratory, genitourinary, idiopathic, and multiple diseases; and pregnancy) with no significant difference (P ≥ 0.05). The disorders most commonly associated with thrombocytosis were gastrointestinal diseases, followed by neoplasms. Furthermore, increased platelet counts were observed in dogs treated with glucocorticoids and vincristine drugs. As for the degree of severity, extreme thrombocytosis occurred more frequently in the presence of gastrointestinal diseases.info:eu-repo/semantics/openAccessUniversidade Federal de GoiásCiência Animal Brasileira v.20 20192019-01-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-68912019000100313en10.1590/1089-6891v20e-51837
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Rocha,Marcela Natacha Aparecida
Rocha,Mayara Carvalho de Sousa
Kavasaki,Mayara Lima
Rodrigues,Juliana Yuki
Souza,Weyber Ferreira de
Mendonça,Adriane Jorge
spellingShingle Rocha,Marcela Natacha Aparecida
Rocha,Mayara Carvalho de Sousa
Kavasaki,Mayara Lima
Rodrigues,Juliana Yuki
Souza,Weyber Ferreira de
Mendonça,Adriane Jorge
THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)
author_facet Rocha,Marcela Natacha Aparecida
Rocha,Mayara Carvalho de Sousa
Kavasaki,Mayara Lima
Rodrigues,Juliana Yuki
Souza,Weyber Ferreira de
Mendonça,Adriane Jorge
author_sort Rocha,Marcela Natacha Aparecida
title THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)
title_short THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)
title_full THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)
title_fullStr THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)
title_full_unstemmed THROMBOCYTOSIS: A RETROSPECTIVE STUDY OF 573 DOGS (2016-2017)
title_sort thrombocytosis: a retrospective study of 573 dogs (2016-2017)
description Abstract Thrombocytosis refers to the increase in number of platelets per microliter (µL) of blood. Platelet counts greater than 1,000,000/µL may be associated with clinical signs of bleeding or thrombosis. Previous studies on underlying causes of thrombocytosis have aroused the interest of researchers about its clinical importance in dogs. The objective of this study was to analyze the blood cell counts in dogs in order to define the main diseases or clinical conditions that were associated with thrombocytosis, from 2016 to 2017. This was done to determine the incidence of thrombocytosis, and categorize the increase in platelet count with respect to severity. Of the 12,676 blood samples analyzed, 4.5% presented thrombocytosis (n = 573). Similar mean platelet counts were observed in all diagnosis or different categories of clinical conditions (neoplasms; gastrointestinal, endocrine, and ophthalmological diseases; trauma and surgery; dermatological, cardiac, neurological, infectious, respiratory, genitourinary, idiopathic, and multiple diseases; and pregnancy) with no significant difference (P ≥ 0.05). The disorders most commonly associated with thrombocytosis were gastrointestinal diseases, followed by neoplasms. Furthermore, increased platelet counts were observed in dogs treated with glucocorticoids and vincristine drugs. As for the degree of severity, extreme thrombocytosis occurred more frequently in the presence of gastrointestinal diseases.
publisher Universidade Federal de Goiás
publishDate 2019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1809-68912019000100313
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