Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review
Abstract Introduction: The relationship between gastroesophageal reflux disease (GERD) and chronic rhinosinusitis (CRS) is still a controversial issue in literature. Objective: A systematic review of the association between these two diseases in adult patients. Methods: Systematic review in PubMed and Cochrane Database with articles published between 1951 and 2015. We included all articles that specifically studied the relationship between CRS and GERD. Results: Of the 436 articles found, only 12 met the inclusion criteria. Eight cross-sectional articles suggest a relation between CRS and GERD, especially on CRS that is refractory to clinical or surgical treatment. However, the groups are small and methodologies are different. Four other longitudinal studies have assessed the effect of treatment with proton pump inhibitors (PPIs) on the improvement of symptoms of CRS, but the results were conflicting. Conclusions: There seems to be relative prevalence of reflux with intractable CRS. There is still a lack of controlled studies with a significant number of patients to confirm this hypothesis. Few studies specifically assess the impact of treatment of reflux on symptom improvement in patients with CRS.
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Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
2017
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oai:scielo:S1808-869420170003003562017-06-26Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic reviewSella,Guilherme Constante PreisTamashiro,EdwinAnselmo-Lima,Wilma TerezinhaValera,Fabiana Cardoso Pereira Rhinosinusitis Laryngopharyngeal reflux Gastroesophageal reflux disease pH-metry Proton pump inhibitor Abstract Introduction: The relationship between gastroesophageal reflux disease (GERD) and chronic rhinosinusitis (CRS) is still a controversial issue in literature. Objective: A systematic review of the association between these two diseases in adult patients. Methods: Systematic review in PubMed and Cochrane Database with articles published between 1951 and 2015. We included all articles that specifically studied the relationship between CRS and GERD. Results: Of the 436 articles found, only 12 met the inclusion criteria. Eight cross-sectional articles suggest a relation between CRS and GERD, especially on CRS that is refractory to clinical or surgical treatment. However, the groups are small and methodologies are different. Four other longitudinal studies have assessed the effect of treatment with proton pump inhibitors (PPIs) on the improvement of symptoms of CRS, but the results were conflicting. Conclusions: There seems to be relative prevalence of reflux with intractable CRS. There is still a lack of controlled studies with a significant number of patients to confirm this hypothesis. Few studies specifically assess the impact of treatment of reflux on symptom improvement in patients with CRS.info:eu-repo/semantics/openAccessAssociação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.Brazilian Journal of Otorhinolaryngology v.83 n.3 20172017-06-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942017000300356en10.1016/j.bjorl.2016.05.012 |
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Sella,Guilherme Constante Preis Tamashiro,Edwin Anselmo-Lima,Wilma Terezinha Valera,Fabiana Cardoso Pereira |
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Sella,Guilherme Constante Preis Tamashiro,Edwin Anselmo-Lima,Wilma Terezinha Valera,Fabiana Cardoso Pereira Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review |
author_facet |
Sella,Guilherme Constante Preis Tamashiro,Edwin Anselmo-Lima,Wilma Terezinha Valera,Fabiana Cardoso Pereira |
author_sort |
Sella,Guilherme Constante Preis |
title |
Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review |
title_short |
Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review |
title_full |
Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review |
title_fullStr |
Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review |
title_full_unstemmed |
Relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review |
title_sort |
relation between chronic rhinosinusitis and gastroesophageal reflux in adults: systematic review |
description |
Abstract Introduction: The relationship between gastroesophageal reflux disease (GERD) and chronic rhinosinusitis (CRS) is still a controversial issue in literature. Objective: A systematic review of the association between these two diseases in adult patients. Methods: Systematic review in PubMed and Cochrane Database with articles published between 1951 and 2015. We included all articles that specifically studied the relationship between CRS and GERD. Results: Of the 436 articles found, only 12 met the inclusion criteria. Eight cross-sectional articles suggest a relation between CRS and GERD, especially on CRS that is refractory to clinical or surgical treatment. However, the groups are small and methodologies are different. Four other longitudinal studies have assessed the effect of treatment with proton pump inhibitors (PPIs) on the improvement of symptoms of CRS, but the results were conflicting. Conclusions: There seems to be relative prevalence of reflux with intractable CRS. There is still a lack of controlled studies with a significant number of patients to confirm this hypothesis. Few studies specifically assess the impact of treatment of reflux on symptom improvement in patients with CRS. |
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Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. |
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2017 |
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http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942017000300356 |
work_keys_str_mv |
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