Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo

INTRODUCTION: Changes in carbohydrate metabolism may lead to recurrence of benign paroxysmal positional vertigo.OBJECTIVE: To evaluate the influence of the disturbance of carbohydrate metabolism in the recurrence of idiopathic BPPV.METHODS: A longitudinal prospective study of a cohort, with 41 months follow-up. We analyzed the results of 72 glucose-insulin curves in patients with recurrence of BPPV. The curves were classified into intolerance, hyperinsulinemia, hyperglycemia and normal.RESULTS: The RR for hyperinsulinism was 4.66 and p = 0.0015. Existing hyperglycemia showed an RR = 2.47, with p = 0.0123. Glucose intolerance had a RR of 0.63, with p = 0.096. When the examination was within normal limits, the result was RR = 0.2225 and p = 0.030.DISCUSSION: Metabolic changes can cause dizziness and vertigo and are very common in people who have cochleovestibular disorders. However, few studies discuss the relationship between idiopathic BPPV and alterations in carbohydrate metabolism. In the present study, we found that both hyperglycemia and hyperinsulinemia are risk factors for the recurrence of BPPV, whereas a normal test was considered a protective factor; all these were statistically significant. Glucose intolerance that was already present was not statistically significant in the group evaluated.CONCLUSION: Hyperinsulinemia and hyperglycemia are risk factors for the recurrence of idiopathic BPPV and a normal exam is considered a protective factor.

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Main Authors: Webster,Guilherme, Sens,Patrícia Maria, Salmito,Márcio Cavalcante, Cavalcante,José Diogo Rijo, Santos,Paula Regina Bonifácio dos, Silva,Ana Lívia Muniz da, Souza,Érica Carla Figueiredo de
Format: Digital revista
Language:English
Published: Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000400347
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spelling oai:scielo:S1808-869420150004003472015-09-02Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigoWebster,GuilhermeSens,Patrícia MariaSalmito,Márcio CavalcanteCavalcante,José Diogo RijoSantos,Paula Regina Bonifácio dosSilva,Ana Lívia Muniz daSouza,Érica Carla Figueiredo de Vertigo Glucose metabolism disorders Carbohydrate metabolism Dizziness INTRODUCTION: Changes in carbohydrate metabolism may lead to recurrence of benign paroxysmal positional vertigo.OBJECTIVE: To evaluate the influence of the disturbance of carbohydrate metabolism in the recurrence of idiopathic BPPV.METHODS: A longitudinal prospective study of a cohort, with 41 months follow-up. We analyzed the results of 72 glucose-insulin curves in patients with recurrence of BPPV. The curves were classified into intolerance, hyperinsulinemia, hyperglycemia and normal.RESULTS: The RR for hyperinsulinism was 4.66 and p = 0.0015. Existing hyperglycemia showed an RR = 2.47, with p = 0.0123. Glucose intolerance had a RR of 0.63, with p = 0.096. When the examination was within normal limits, the result was RR = 0.2225 and p = 0.030.DISCUSSION: Metabolic changes can cause dizziness and vertigo and are very common in people who have cochleovestibular disorders. However, few studies discuss the relationship between idiopathic BPPV and alterations in carbohydrate metabolism. In the present study, we found that both hyperglycemia and hyperinsulinemia are risk factors for the recurrence of BPPV, whereas a normal test was considered a protective factor; all these were statistically significant. Glucose intolerance that was already present was not statistically significant in the group evaluated.CONCLUSION: Hyperinsulinemia and hyperglycemia are risk factors for the recurrence of idiopathic BPPV and a normal exam is considered a protective factor.info:eu-repo/semantics/openAccessAssociação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.Brazilian Journal of Otorhinolaryngology v.81 n.4 20152015-08-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000400347en10.1016/j.bjorl.2014.09.008
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country Brasil
countrycode BR
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databasecode rev-scielo-br
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libraryname SciELO
language English
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author Webster,Guilherme
Sens,Patrícia Maria
Salmito,Márcio Cavalcante
Cavalcante,José Diogo Rijo
Santos,Paula Regina Bonifácio dos
Silva,Ana Lívia Muniz da
Souza,Érica Carla Figueiredo de
spellingShingle Webster,Guilherme
Sens,Patrícia Maria
Salmito,Márcio Cavalcante
Cavalcante,José Diogo Rijo
Santos,Paula Regina Bonifácio dos
Silva,Ana Lívia Muniz da
Souza,Érica Carla Figueiredo de
Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo
author_facet Webster,Guilherme
Sens,Patrícia Maria
Salmito,Márcio Cavalcante
Cavalcante,José Diogo Rijo
Santos,Paula Regina Bonifácio dos
Silva,Ana Lívia Muniz da
Souza,Érica Carla Figueiredo de
author_sort Webster,Guilherme
title Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo
title_short Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo
title_full Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo
title_fullStr Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo
title_full_unstemmed Hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo
title_sort hyperinsulinemia and hyperglycemia: risk factors for recurrence of benign paroxysmal positional vertigo
description INTRODUCTION: Changes in carbohydrate metabolism may lead to recurrence of benign paroxysmal positional vertigo.OBJECTIVE: To evaluate the influence of the disturbance of carbohydrate metabolism in the recurrence of idiopathic BPPV.METHODS: A longitudinal prospective study of a cohort, with 41 months follow-up. We analyzed the results of 72 glucose-insulin curves in patients with recurrence of BPPV. The curves were classified into intolerance, hyperinsulinemia, hyperglycemia and normal.RESULTS: The RR for hyperinsulinism was 4.66 and p = 0.0015. Existing hyperglycemia showed an RR = 2.47, with p = 0.0123. Glucose intolerance had a RR of 0.63, with p = 0.096. When the examination was within normal limits, the result was RR = 0.2225 and p = 0.030.DISCUSSION: Metabolic changes can cause dizziness and vertigo and are very common in people who have cochleovestibular disorders. However, few studies discuss the relationship between idiopathic BPPV and alterations in carbohydrate metabolism. In the present study, we found that both hyperglycemia and hyperinsulinemia are risk factors for the recurrence of BPPV, whereas a normal test was considered a protective factor; all these were statistically significant. Glucose intolerance that was already present was not statistically significant in the group evaluated.CONCLUSION: Hyperinsulinemia and hyperglycemia are risk factors for the recurrence of idiopathic BPPV and a normal exam is considered a protective factor.
publisher Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942015000400347
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