Laryngeal chondrosarcoma - Ten years of experience

INTRODUCTION: Laryngeal involvement by cartilaginous tumors is rare. However, although accounting for only 1% of laryngeal tumor pathology, they are the most frequently occurring non-epithelial neoplasms. The most probable location is the endolaryngeal surface of the cricoid cartilage. Their symptoms are variable, depending on the size and location, and may include hoarseness, stridor, and dyspnea. Treatment is based on surgical excision. Some centers take into account the degree of differentiation and whether it is a case of relapse when deciding to perform a radical resection. AIM: To evaluate this disease in a sample of the Portuguese population. METHODS: A review of the medical records from 2002 to 2012 by assessment of clinical processes was performed. Data on demographics, clinical treatments, and outcomes were collected. RESULTS: Six patients were included in the study. Five of them underwent total laryngectomy, and in one case, partial excision of the thyroid cartilage was performed. None of the patients had either metastases or tumor-related death. CONCLUSION: Laryngeal chondrosarcomas remain a rare disease of unknown etiology, with slow and insidious symptoms. The treatment is surgical, with favorable prognosis, and metastases rarely occur. The main concern regards their propensity to relapse.

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Main Authors: Oliveira,José Fernando dos Santos, Branquinho,Francisco António Pinto Lopes, Monteiro,Ana Rita Raposeiro Tomé Nobre, Portugal,Maria Edite Correia Castro, Guimarães,Arnaldo Manuel Ferreira Silva
Format: Digital revista
Language:English
Published: Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. 2014
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942014000400354
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spelling oai:scielo:S1808-869420140004003542015-08-25Laryngeal chondrosarcoma - Ten years of experienceOliveira,José Fernando dos SantosBranquinho,Francisco António Pinto LopesMonteiro,Ana Rita Raposeiro Tomé NobrePortugal,Maria Edite Correia CastroGuimarães,Arnaldo Manuel Ferreira Silva Chondrosarcoma Laryngeal neoplasms Larynx INTRODUCTION: Laryngeal involvement by cartilaginous tumors is rare. However, although accounting for only 1% of laryngeal tumor pathology, they are the most frequently occurring non-epithelial neoplasms. The most probable location is the endolaryngeal surface of the cricoid cartilage. Their symptoms are variable, depending on the size and location, and may include hoarseness, stridor, and dyspnea. Treatment is based on surgical excision. Some centers take into account the degree of differentiation and whether it is a case of relapse when deciding to perform a radical resection. AIM: To evaluate this disease in a sample of the Portuguese population. METHODS: A review of the medical records from 2002 to 2012 by assessment of clinical processes was performed. Data on demographics, clinical treatments, and outcomes were collected. RESULTS: Six patients were included in the study. Five of them underwent total laryngectomy, and in one case, partial excision of the thyroid cartilage was performed. None of the patients had either metastases or tumor-related death. CONCLUSION: Laryngeal chondrosarcomas remain a rare disease of unknown etiology, with slow and insidious symptoms. The treatment is surgical, with favorable prognosis, and metastases rarely occur. The main concern regards their propensity to relapse. info:eu-repo/semantics/openAccessAssociação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.Brazilian Journal of Otorhinolaryngology v.80 n.4 20142014-08-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942014000400354en10.1016/j.bjorl.2014.05.004
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country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Oliveira,José Fernando dos Santos
Branquinho,Francisco António Pinto Lopes
Monteiro,Ana Rita Raposeiro Tomé Nobre
Portugal,Maria Edite Correia Castro
Guimarães,Arnaldo Manuel Ferreira Silva
spellingShingle Oliveira,José Fernando dos Santos
Branquinho,Francisco António Pinto Lopes
Monteiro,Ana Rita Raposeiro Tomé Nobre
Portugal,Maria Edite Correia Castro
Guimarães,Arnaldo Manuel Ferreira Silva
Laryngeal chondrosarcoma - Ten years of experience
author_facet Oliveira,José Fernando dos Santos
Branquinho,Francisco António Pinto Lopes
Monteiro,Ana Rita Raposeiro Tomé Nobre
Portugal,Maria Edite Correia Castro
Guimarães,Arnaldo Manuel Ferreira Silva
author_sort Oliveira,José Fernando dos Santos
title Laryngeal chondrosarcoma - Ten years of experience
title_short Laryngeal chondrosarcoma - Ten years of experience
title_full Laryngeal chondrosarcoma - Ten years of experience
title_fullStr Laryngeal chondrosarcoma - Ten years of experience
title_full_unstemmed Laryngeal chondrosarcoma - Ten years of experience
title_sort laryngeal chondrosarcoma - ten years of experience
description INTRODUCTION: Laryngeal involvement by cartilaginous tumors is rare. However, although accounting for only 1% of laryngeal tumor pathology, they are the most frequently occurring non-epithelial neoplasms. The most probable location is the endolaryngeal surface of the cricoid cartilage. Their symptoms are variable, depending on the size and location, and may include hoarseness, stridor, and dyspnea. Treatment is based on surgical excision. Some centers take into account the degree of differentiation and whether it is a case of relapse when deciding to perform a radical resection. AIM: To evaluate this disease in a sample of the Portuguese population. METHODS: A review of the medical records from 2002 to 2012 by assessment of clinical processes was performed. Data on demographics, clinical treatments, and outcomes were collected. RESULTS: Six patients were included in the study. Five of them underwent total laryngectomy, and in one case, partial excision of the thyroid cartilage was performed. None of the patients had either metastases or tumor-related death. CONCLUSION: Laryngeal chondrosarcomas remain a rare disease of unknown etiology, with slow and insidious symptoms. The treatment is surgical, with favorable prognosis, and metastases rarely occur. The main concern regards their propensity to relapse.
publisher Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial.
publishDate 2014
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1808-86942014000400354
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