Stroke risk among patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis
Increased stroke risk among chronic obstructive pulmonary disease patients has not yet been established. In this study, we conducted a systematic review and meta-analysis to assess stroke risk among chronic obstructive pulmonary disease patients. PubMed, EMBASE, and the Cochrane Library were systematically searched from database inception until December 31, 2016 to identify longitudinal observational studies that investigated the association between chronic obstructive pulmonary disease and stroke. Stroke risk was quantified by overall and subgroup analyses, and a pooled hazard ratio was calculated. Study quality was evaluated using the Newcastle-Ottawa Scale. Publication bias was assessed using Begg’s rank correlation test. Eight studies met the inclusion criteria. In a random-effects model, significantly increased stroke risk was observed among chronic obstructive pulmonary disease patients (hazard ratio, 1.30; 95% confidence interval, 1.18-1.43). In subgroup analyses stratified by stroke subtype, study quality, and adjustment by socioeconomic status, the association between increased stroke risk and chronic obstructive pulmonary disease patients was robust. Statistically significant publication bias was not detected. In summary, chronic obstructive pulmonary disease was found to be associated with increased stroke risk. Additional prospective studies are required to elucidate the mechanisms underlying the increase in stroke risk and identify effective preventive interventions.
Main Authors: | Kim,Yu Ree, Hwang,In Cheol, Lee,Yong Joo, Ham,Eun Bee, Park,Dong Kyun, Kim,Sewan |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Faculdade de Medicina / USP
2018
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100302 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Risk factors for bronchiectasis in patients with chronic obstructive pulmonary disease: a systematic review and meta-analysis
by: Zhang,XinXin, et al.
Published: (2021) -
Epidemiology of Chronic Obstructive Pulmonary Disease in Brazil: a systematic review and meta-analysis
by: Cruz,Marina Malheiro, et al.
Published: (2020) -
Home or community-based pulmonary rehabilitation for individuals with chronic obstructive pulmonary disease: a systematic review and meta-analysis
by: Neves,Leonardo Fratti, et al.
Published: (2016) -
Pulmonary rehabilitation following exacerbations of chronic obstructive pulmonary disease
by: Puhan,Milo, et al.
Published: (2009) -
Clinical Epidemiology of Chronic Obstructive Pulmonary Disease
by: Mascarenhas,Joana, et al.
Published: (2011)